Navigation Links
Virus may Be the Cause of Mad Cow

A study disputes the theory that deformed proteins are to blame for the brain disease. According to a study released Monday, Mad Cow disease and other related brain disorders// may be caused by a virus and not the weird, misshapen proteins, known as prions, that scientists think are responsible.

Researchers reported that they found virus-like particles in mouse nerve cells infected with two brain-wasting diseases similar to mad cow disease, but found no traces of the particles in uninfected cells.

Lead author Dr. Laura Manuelidis, a neuropathologist at Yale University, said the finding suggested that prions in infected brains were the result of a viral infection and not the cause of the disease.

"We found something that people have been ignoring," Manuelidis said of the virus particles. "What we hypothesize is the simplest, most parsimonious point of view."

Several brain researchers were skeptical about Manuelidis' findings, published in the Proceedings of the National Academy of Sciences.

"It's very remarkable that we only see these particles after infection of these cells," said Bob Rohwer, director of the Molecular Neurovirology Laboratory at the Veterans Affairs Medical Center in Baltimore, who was not involved in the study. "But the evidence that they are in fact the infectious agent responsible is still highly circumstantial."

Mad cow disease, known formally as bovine spongiform encephalopathy, is a cattle disease that destroys brain tissue by causing abnormal tangles of protein fibers and creating microscopic holes in the brain.

It is part of a family of slow-developing brain diseases, including scrapie in sheep and Creutzfeldt-Jakob disease in humans. Human infection in recent years has been connected to eating infected meat. There have been dozens of fatalities over the years.

The prion theory of mad cow disease proposes that a normal protein spontaneously misfol ds, starting a cascade of abnormal changes in other proteins.

In Manuelidis' previous experiments, prions did not appear until late in the progression of spongy brain diseases.

To find what appears at an earlier phase, Manuelidis' team homogenized mouse brains infected with scrapie and Creutzfeldt-Jakob disease and injected them into nerve cell cultures.

The only new objects were dense spheres that looked like small viruses, she said.

She later added a compound to spur the growth of prions about fivefold to see if that would increase the level of infection. The level did not show a significant increase, suggesting that prions were not the active agent of infection, she said.

To prove that the virus-like particles are solely responsible for the infection, Manuelidis plans to isolate the particles and see if they can start an infection when injected into healthy cells.

Source-Bio-Bio Technology
SRI
'"/>




Related medicine news :

1. Virus Level could Predict Cervical Cancer Risk
2. Ebola Virus - Outbreak Claims More Lives In Uganda.
3. Experimental treatment for Ebola Virus Shows promising results in mice
4. Virus Combats Brain Tumour
5. Virus killer
6. Pain Killers Keep the Virus Away
7. Measles Suppresses AIDS Virus
8. Virus connection to cervical injury
9. Virus Helps Remove Brain Cancer
10. Origin Of SARS Virus Discovered
11. New Molecule that can stop the growth of Viruses
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:5/1/2016)... ... May 01, 2016 , ... Women's Excellence in Wellness, powered by Movestrong, will ... Dolan, a Young Living Gold Member. , The class will be held Tuesday, May ... small intro to the Oils that can benefit participant's yoga practice, as well as ...
(Date:4/30/2016)... ... May 01, 2016 , ... Serenity Recovery, a substance abuse ... produced a new video that focuses on one of the more popular of their ... clips from interviews with a participating patients and the Yoga class instructor, this video ...
(Date:4/30/2016)... ... April 30, 2016 , ... ... President and CEO of EMED, today signed a multifaceted agreement which will allow ... the Northern Caribbean University Department of Natural and Applied Sciences, Allied Health and ...
(Date:4/29/2016)... , ... April 30, 2016 , ... Mercy College is ... The following programs will be expanding due to high demand: Master of Business ... expansion will begin this summer. , School of Business Graduate Program Chair ...
(Date:4/29/2016)... ... April 29, 2016 , ... Our bodies are bombarded daily by environmental ... deal with these stressors is to adopt a more healthful diet, but too many ... Groux, a certified Holistic Nutritionist and the creator of the Newport Beach Cleanse and ...
Breaking Medicine News(10 mins):
(Date:4/27/2016)... , April 27, 2016 ... titled, "Skincare Devices Market - Global Industry Analysis, Size, ... to the report, the global skincare devices market was ... anticipated to expand at a CAGR of 10.1% from ... 2023. Browse the full Skincare Devices Market (Treatment ...
(Date:4/27/2016)... 27, 2016  Bayer Animal Health today announced ... the University of Florida College of Veterinary Medicine, ... in Communication Award (BECA). Brittany was selected from ... a total of $70,000 in scholarship funds through ... Bayer has provided a total of $232,500 in ...
(Date:4/27/2016)... 27, 2016 Oasmia Pharmaceutical ... of a new generation of drugs within human ... results for Paclical/Apealea in the Phase III study ... epithelial ovarian cancer. These preliminary results showed non-inferiority ... with carboplatin versus Taxol in combination with carboplatin. ...
Breaking Medicine Technology: