Navigation Links
Virtual Colonoscopy is Most-effective for Screening Colon Cancer

A new study says targeting smaller lesions does little to significantly reduce the incidence of colorectal cancer (CRC) and, in fact, results in extremely high// financial costs and a large proportion of adverse events. A cost-benefit analysis study says the low malignancy rate among so-called diminutive polyps gives virtual colonoscopy with removal of lesions 6 mm or greater the best estimated value per life year gained and with fewer complications.

Effective screening through increased use of any of several available tests is the key to reducing deaths from colorectal cancer, the third leading cause of cancer death in both men and women. Despite the availability of effective screening tests, screening rates remain low and CRC-related deaths remain high.

Optical colonoscopy (OC) and flexible sigmoidscopy (FS) have been the primary screening tools for the last few decades but are associated with complications ¨C from abdominal pain to life-threatening bowel perforation and bleeding. Virtual colonoscopy, or CT colonography (CTC), has arisen as a potentially effective CRC screening tool. Using x-rays and imaging software to develop two- and three-dimensional images of the gastrointestinal tract, it has fewer adverse effects and is better tolerated by patients. Recent studies using new methods have demonstrated that the test is very sensitive for CRC and could be an effective screening option for patients.

Previous cost-benefit analysis studies comparing OC and CTC (with OC referral for all polyps of any size) have estimated that OC is more cost effective. However, these studies ignore current CTC guidelines that recommend only reporting polyps greater than 5 mm. Dr. Perry Pickhardt, a radiologist from the University of Wisconsin, collaborated with Dr. Cesare Hassan, a gastroenterologist from Rome, and colleagues to conduct a cost-benefit analysis comparing CTC with and without a 6-mm polyp size threshold, OC and FS.

In t his model of 100,000 persons over 50 years old, CTC with OC follow-up of polyps greater than 5 mm was the most cost-effective screening test. According to cost per life-year gained calculations, CTC with a 6-mm threshold for follow-up cost only $4,361 while OC cost $9,180 per life-year gained. CTC with no polyp size threshold cost $7,138, and FS cost $7,407 per life-year gained.

The incremental costs of working-up lesions smaller than 6 mm at CTC resulted in a significant $118,440 per additional life-year gained and accounted for more than half of all OC procedures. Moreover, working up these small, almost always benign polyps with OC caused considerable complications. The study found almost half of all OC-related complications were attributable to work-up of diminutive lesions. Furthermore, targeting these lesions did not improve screening efficacy, reducing CRC incidence by only 1.3 percent.

The authors say the data support "CTC with nonreporting of diminutive lesions" to be "the most cost-effective and safest screening option available." "Providing additional effective yet distinct screening options like CTC could encourage more adults to undergo screening," conclude the authors, and consequently "increase overall compliance with screening" for CRC.

Source-Eurekalert/M
'"/>




Related medicine news :

1. Stanford Medical Center Implements The First Virtual Cardiac Ultrasound
2. Virtual Colonoscopy May Be Better Than Real-time Colonoscopy
3. Virtual Reality For Treating Stress Disorders
4. Hip Replacement Can Now Be Performed On Virtual Patients
5. Virtual Reality Simulation Could Help In Training Surgeons
6. New Studies Show The Efficacies Of Virtual Realities Vis-à-vis Pai
7. Virtual Meeting Place Unites Patients with Brain Tumors and Neurosurgical Disorders
8. Virtual Colonoscopy in Colorectal Cancer Prevention and Screening
9. The Tech Savvy Patient Knocks on the Doors of Telemedicine and Virtual Clinics
10. Colonoscopy Could Also Identify Heart Attack Risk
11. Colonoscopy may be better to detect colon cancer in women
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:4/29/2016)... ... April 29, 2016 , ... The American workforce ... stability, even security. Most importantly, employees are the single most important asset in ... workers so unhappy? , Just under half of American workers are emotionally checked ...
(Date:4/29/2016)... ... April 29, 2016 , ... Conditions were ideal for Global Lyme ... on Sunday, with sunny skies, a light breeze and temperatures in the 60s. Over ... The 5k Run and Walk and 1-mile walk were held to increase awareness ...
(Date:4/29/2016)... , ... April 29, 2016 , ... Spine Team Texas, ... is proud to announce one of their physicians has been invited to be a ... (Texas ACOFP) Family Practice Review conference on April 30, 2016. , Dr. R. ...
(Date:4/29/2016)... NY (PRWEB) , ... April 29, 2016 , ... ... and engineer of patented products, announces the Gyrociser, an exercise invention which aids ... worth $2 billion," says Scott Cooper, CEO and Creative Director of World Patent ...
(Date:4/29/2016)... ... April 29, 2016 , ... Dr. Robert Mondavi, one of the ... Cosmetic dentistry is a fast-growing field as more patients are discovering the many different ... more about the options currently available to them and which ones might work for ...
Breaking Medicine News(10 mins):
(Date:4/27/2016)... --   , Total Sales ... Sales  Clinical sales grow 16% year-over-year  , ... OTCQX: MKEAY) inventor of Cellvizio®, the multidisciplinary confocal laser ... quarter ended March 31, 2016 and provided an update ... strategy. First Quarter 2016 Revenue Results by ...
(Date:4/27/2016)... , April 27, 2016 ... titled, "Skincare Devices Market - Global Industry Analysis, Size, ... to the report, the global skincare devices market was ... anticipated to expand at a CAGR of 10.1% from ... 2023. Browse the full Skincare Devices Market (Treatment ...
(Date:4/27/2016)... NEW DELHI , April 27, 2016 ... CSR initiative to save newborns ... ,s hospital for women & newborns in collaboration with Breast ... has launched the first Pasteurized Human Milk Bank, ,Amaara, in ... the best nutritional food source for infants and should be ...
Breaking Medicine Technology: