Navigation Links
Vietnam Plans Human Trial of Bird Flu Vaccine

Vietnam plans to start its first human trial of a locally-made H5N1 bird flu vaccine as early as next month, using 20 to 30 volunteers, said health officials in the communist country. The drug trial, to be carried out with US government technical assistance, will be the latest of several global efforts to develop a vaccine for mass production, with research also going on in the United States, Europe and Asia.

The news comes as a new wave of bird flu sweeping Vietnam has killed a 20-year-old man, infected four other people and triggered more than 100 poultry outbreaks nationwide since last month. "Preparations for the clinical test of a human vaccine have been basically completed," said Nguyen Tran Hien, director of the National Institute of Hygiene and Epidemiology (NIHE) in Hanoi.

"Twenty to 30 volunteers will be chosen to test an H5N1 vaccine produced in Vietnam." Hien said he expected testing to start as early as next month, pending health ministry approval, with the trial expected to wrap up next year. In the tests, subjects would not be exposed to H5N1 -- the viral strain that has killed 191 people worldwide since 2003 -- but would be given the vaccine to look for early evidence of safety and test their antibody response. US experts would provide technical assistance, said US Health Attache Michael Iademarco, adding Washington had granted one million dollars to Vabiotech, a company spun off from the institute.

The Vietnam trial is one of several efforts worldwide to find a vaccine that could be mass produced in case of a pandemic. Last month Indonesia's health ministry said US company Baxter Healthcare would in July start clinical trials of a bird flu vaccine in Singapore and Hong Kong, using a strain of the virus found in Indonesia. "There are many candidate vaccines, and some have been approved for stockpiling in emergency use," said Iademarco. But he said the long-term challenge was to "develop the capacity for rapi d mass production."

The NIHE project is one of Vietnam's three research drives for a bird flu vaccine, along with work at the Pasteur Institute in Ho Chi Minh City and at the national vaccine producer IVAC in Nha Trang. In April the World Health Organisation (WHO) said Vietnam, Indonesia, Thailand, Brazil, India and Mexico would receive grants to produce flu vaccine locally and bolster global protection against a threatened pandemic. WHO's Vietnam chief Hans Troedsson said the UN body was "looking favourably" at a request to grant the IVAC project up to 2.5 million dollars.

Avian influenza has so far tended to infect people in close contact with H5N1-positive birds, but experts fear the virus could mutate to be more easily transmitted from human to human, triggering a global pandemic. Iademarco praised Vietnam for launching three different research projects in the search for a human avian influenza vaccine. "Each one of these three vaccines has a different background in biology, and I actually think it's smart that Vietnam is investing in three technologies at this early stage in research and development," he said. He cautioned that developing an H5N1 vaccine was a complex task. "It's not like seasonal flu where we can vaccinate 10,000 people and figure out if it's working or not," he said.

"The challenge with a pandemic influenza vaccination is that you have to work just as quickly, you don't have the experience behind you, and the consequences of failure are much higher." The trials would improve the skills of Vietnamese epidemiologists and help the country deal with future health threats, including dangerous new strains of the flu, Iademarco said. Vietnam's long-term goal, he said, "is to develop influenza vaccine capacity, because it's H5N1 today, but who knows what it's going to be tomorrow in terms of a virus with pandemic potential?"


'"/>




Related medicine news :

1. WHO Declares Vietnam First Country to Control SARS
2. Vietnamese Scientists Unravel Genetic Code Of Bird Flu Virus
3. Vaccination to fowl in Vietnam reduced the spread of bird flu
4. Financial Allowances Being Offered To Poor Vietnamese HIV Carriers
5. Bird flu virus spreading in Vietnam
6. Vietnam administers Bird flu vaccination to all birds
7. Chirps of Wisdom: Taking a Leaf out Of Vietnam’s Bird-Flu Sag
8. Link Between Vietnam Service And Prostate Cancer Is Statistically Insignificant
9. Rubella Outbreak Grips Vietnam
10. WHO Praises Singapore and Vietnam but Slams China With Respect To Tackling SARS
11. Foot and Mouth Raises Its Ugly Head in Vietnam
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:5/28/2016)... ... ... a year and a half of planning the Multiple Pathways of Recovery Conference , ... Recovery Conference was held May 2 -4, 2016 at the Mystic Marriott Hotel & ... explore the many pathways individuals use to get into and sustain their recovery. Pathways ...
(Date:5/27/2016)... Los Angeles, CA (PRWEB) , ... May 27, 2016 , ... ... Institutes of Health, so it is not surprising that bariatric surgery has received increased ... Baltimore Business Journal explains. Of course, when it comes to weight loss, most people ...
(Date:5/27/2016)... ... May 27, 2016 , ... Two director-level employees of Horizon Blue Cross ... and Industry (TWIN) 2016 honorees. The award recognizes businesswomen who excel in their ... Boone, Director of the MLTSS (Managed Long-Term Services and Supports) Program at Horizon NJ ...
(Date:5/27/2016)... New York, NY (PRWEB) , ... May 27, 2016 , ... ... annual campaign returns for a third time to shed lights on the variety of ... resources and inspirational stories, “Nurse Appreciation” tackles why this career has gone from being ...
(Date:5/27/2016)... ... May 27, 2016 , ... This campaign aims to provide a ... as a society can control and change. , As nearly 795,000 Americans suffering from ... within the United States. Plus, with an estimated 129,000 of these people dying from ...
Breaking Medicine News(10 mins):
(Date:5/27/2016)... , May 27, 2016 According ... of hypertension is driving ambulatory blood pressure monitoring system ... elasticity and their ability to respond to different pressure ... condition can lead to various cardiovascular disorders such as ... disease. These diseases are growing in prevalence each year. ...
(Date:5/26/2016)... , May 26, 2016 According to ... Waste Management Market - U.S. Industry Analysis, Size, Share, Growth, ... market in the U.S. was valued at US$ 5.89 Bn ... of 3.4% from 2015 to 2023 to reach US$ 7.99 ... of current and emerging needle free drug delivery devices and ...
(Date:5/25/2016)... PARIS , May 25,2016 ... with the near-infrared Cellvizio platform for urological and ... MKEA, OTCQX: MKEAY) inventor of Cellvizio®, the multidisciplinary ... important regulatory milestone in the US with the ... Food and Drug Administration (FDA). This new FDA ...
Breaking Medicine Technology: