Navigation Links
Valve Disease Study Suggests New Public Health Concern

Research from Mayo Clinic estimates that about 5 million adult Americans have moderate or severe heart valve disease as a consequence of aging, according to a Mayo Clinic study// published online in The Lancet.

While rheumatic fever was previously the main cause of valve diseases and was a major public health issue even in the middle of the 20th century, rheumatic fever is not a serious concern in this country today, thanks to antibiotic therapy and improved living standards.

“Valve diseases are a significant public health concern because the proportion of our elderly population is increasing,” says Vuyisile Nkomo, M.D., cardiologist and lead author of the study. “This study shows that valve diseases increase significantly with aging. It is a major step in understanding the scope of the burden of valve diseases today and their contribution to declining health with aging.”

Physicians have suspected the increase in valvular disease, but Mayo’s research is the first comprehensive study to look at data from the general population and the community. Data from the general population reveals information on systematic samples of individuals to reveal trends; data from the community -- in this case, Olmsted County, where Mayo Clinic is based -- provides information on people who have already been offered clinical attention for an illness.

Researchers used data from echocardiograms from the general population of 11,911 participants in three National Heart, Lung and Blood Institute-funded population studies: the Coronary Artery Risk Development in Young Adults (CARDIA) Study, the Atherosclerosis Risk in Communities (ARIC) Study, and the Cardiovascular Health Study (CHS). Researchers also analyzed data from Olmsted County of adults who had been assessed by clinically indicated echocardiograms.

In the general population studies, the prevalence of adults diagnosed with moderate or severe valve disease increased with age , from 0.7 percent in 18- to 44-year-olds to 13.3 percent in those 75 and older. The projected national estimate of valve diseases based on the age and gender distribution of the 2000 U.S. population census is 2.5 percent of adults or approximately 5 million people.

In Olmsted County, 1.8 percent (adjusted to U.S. census figures) of the adults were diagnosed with valve disease and prevalence also increased with age, from 0.3 percent in the 18- to 44-year-olds to 11.7 percent of those 75 and older. Remarkably, the prevalence of valve disease was similar in the population but in the community, valve disease was diagnosed less in women, suggesting a possible gender bias and the need for further study, Dr. Nkomo says.

“The results of this study are not trivial. We predict -- in view of the growth and aging of the population -- that the number of U.S. patients with valve disease will double in the next 20 years,” says co-author Maurice Enriquez-Sarano, M.D., also a Mayo Clinic cardiologist.

An echocardiogram -- a noninvasive test that uses sound waves to create a moving picture of the heart -- is done to evaluate murmurs or causes of shortness of breath or chest pain or heart failure, and is ideal for detecting or confirming valve diseases, Dr. Nkomo says.

Valve diseases are referred to as silent killers in part because a person can have severe valve disease without having symptoms, and it may take some time before there is heart failure. “When physicians diagnose valve disease in the elderly, we hesitate to perform surgery because of the risks involved,” Dr. Nkomo says.

But research shows that cardiac surgery for valve disease has now much improved results, particularly in the elderly, says Dr. Enriquez-Sarano, pointing to Mayo Clinic research published in the July 17 issue of Circulation. While elderly patients undergoing valve surgery have higher risks of operation, they benefited from the surgery as much as younger patients, and operative risks in elderly patients over the 16-year study period declined considerably, says Dr. Enriquez-Sarano, an author of that study.

“We hope our data will generate further research to unravel why some people get valve diseases with aging and some others do not,” he says. “Also, while we are raising concerns about the re-emergence of valve diseases, there are outstanding established treatments and tremendous efforts to find less invasive ways to treat valve diseases and bring about new treatments so we can prolong and improve the quality of life of patients affected by valve diseases.”

(Source Newswise)

Related medicine news :

1. Cardiac Valve Disease Linked To Genes
2. ResQ-Valve With CPR In Cardiac Arrest Patients To Be Assessed By National Study
3. "Umbrella" Valve Provides Potential Alternative to Lung Surgery
4. First Keyhole Heart Valve Surgery Scheduled in Britain
5. Transdermal HRT not cardioprotective in postmenopausal women with Coronary Artery Disease
6. Vitamins-The answer to Heart Disease?
7. Link between Constipation and Parkinsons Disease
8. Levels Of Blood Proteins May Help Heart Disease Care
9. New Drug PP188 Helps Sickle Cell Disease
10. Gene Treatment for Heart Disease
11. Legume Consumption Can Cut Heart Disease Risk
Post Your Comments:

(Date:11/26/2015)... Ashburn, VA (PRWEB) , ... November 26, 2015 ... ... Planners, an American Express Travel Representative. As a franchise owner, Somu now offers ... range of cruise, destination wedding packages, private cruise sales, as well as, cabin ...
(Date:11/26/2015)... ... 26, 2015 , ... WorldCare International, Inc., the first company ... Employee Benefits Conference. The Employee Benefits Conference was hosted by the International Foundation ... 11th, 2015. The conference was held at the Hawaii Convention Center in Honolulu, ...
(Date:11/25/2015)... ... November 25, 2015 , ... Additional breast cancers ... on mammography, according to a study published online in the journal Radiology. Researchers ... mammography may necessitate a change in treatment. , Breast MRI is the most ...
(Date:11/25/2015)... ... November 25, 2015 , ... Medical ... once again for its stellar workplace culture with the company’s Cincinnati office being ... Medical Solutions’ Cincinnati office was named a finalist in Cincinnati Business Courier’s 13th ...
(Date:11/25/2015)... ... November 25, 2015 , ... On November 10, 2015, Bohrer Brady, ... of Connecticut on behalf of a home health care worker who provided companionship services ... home health care workers employed by Humana, Inc., Humana at Home, Inc., and SeniorBridge ...
Breaking Medicine News(10 mins):
(Date:11/26/2015)... 3D bioprinting market is expected to reach ... by Grand View Research Inc. Rising prevalence of chronic diseases ... is expected to boost the market growth, as 3D bioprinting ... --> 3D bioprinting market is expected to reach ... by Grand View Research Inc. Rising prevalence of chronic diseases ...
(Date:11/26/2015)... , November 26, 2015 ... of the "2016 Future Horizons and ... Abuse Testing Market: Supplier Shares, Country Segment ... to their offering. --> ... "2016 Future Horizons and Growth Strategies ...
(Date:11/26/2015)... 26, 2015 ... "2016 Future Horizons and Growth Strategies ... Market: Supplier Shares, Country Segment Forecasts, Competitive ... offering. --> ) has ... Future Horizons and Growth Strategies in the ...
Breaking Medicine Technology: