Navigation Links
Valium hits 40 years old, anxiety-free

Valium, the drug that revolutionized the treatment of anxiety and became a cultural icon, is 40 years old this year.
The drug owes its success to the stubborn streak of chemist Leo Sternbach, who refused to quit after his boss at Hoffmann-La Roche ended a project to develop a tranquilizer to compete with a rival company's drug. Sternbach tested one last version and in just a day, he got the results: The compound made animals relaxed and limp.//

Sternbach had made the discovery that eventually led to Valium. It was approved for use in 1963 and became the country's most prescribed drug from 1969 to 1982. Valium also was referred to as a "doll" -- one of the pills popped by female characters in novelist Jacqueline Susann's racy 1966 best-seller "Valley of the Dolls." Most of the prescriptions were written by family doctors rather than psychiatrists, and the majority of users were women.

With Valium, Sternbach gave the company its first blockbuster. Sternbach had created an entire new class of tranquilizers named benzodiazepines, which were safer and more effective than previous treatments such as barbiturates, opiates, alcohol and herbs. Unlike earlier drugs, Valium did not slow breathing, so patients couldn't use it to commit suicide. But it was overused, Sternbach said; some patients became addicted, so a doctor's visit was required for refills.

Still, benzodiazepines remain the most prescribed anxiety drugs, partly because they start working as fast as one hour, slowing brain activity. They also are used for treating panic and phobia disorders and insomnia, calming patients before surgery and relaxing muscles. Sternbach officially retired in 1973, but worked most days until recently. He mentored young scientists, corresponded and consulted with others, and worked on his biography, due out this fall under the title, "Good Chemistry: The Life and Times of Valium Inventor Leo Sternbach." Sternbach's credits include 241 patents, 122 pu blications, honorary degrees and other awards. His other breakthroughs include the sleeping pills Dalmane and Mogadon, Klonopin for epileptic seizures and Arfonad, for limiting bleeding during brain surgery.

"He's an inventor's inventor," "Within every company, there is a person or two whose legacy becomes the hallmark of what the company is about, and for Roche, it is Dr. Sternbach."
'"/>




Related medicine news :

1. Test tube babies, 25 years later
2. Diabetes cases could double in developing countries in next 30 years
3. Larynx transplant restores patients voice after 20 years
4. New Blood Thinner Pill - First Potential Alternative to Warfarin in 50 years
5. Microbicides could serve to materialise women empowerment in the years to come
6. Diagnosis of Alzheimers years before clinical signs emerge
7. Induced abortion results in years of trauma.
8. 10 Million Indian Females Aborted In 20 years
9. Loss and damage to the brain cells possible with lead exposure in years ahead
10. Womb transplantation- to be successful in 2 years’ tim
11. Babies under two years of age to be administered Meningitis vaccination
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/27/2016)... California (PRWEB) , ... June ... ... pioneer in the patient payment industry today announced its strategic partnership with ... health system workflows. , The two companies’ proven, proprietary technology combine to ...
(Date:6/26/2016)... ... 27, 2016 , ... Quality metrics are proliferating in cancer care, and are ... the eye of the beholder, according to experts who offered insights and commentary in ... Managed Care. For the full issue, click here . , For the American ...
(Date:6/26/2016)... ... June 26, 2016 , ... PawPaws brand pet supplements owned by ... to enhance the health of felines. The formula is all-natural and is made from ... the PawPaws Cat Kidney Support Supplement Soft Chews are Astragalus Root Extract ...
(Date:6/25/2016)... , ... June 25, 2016 , ... ... policy issues and applications at AcademyHealth’s Annual Research Meeting June 26-28, 2016, at ... on several important health care topics including advance care planning, healthcare costs and ...
(Date:6/25/2016)... California (PRWEB) , ... June 25, 2016 , ... "With ... fit their specific project," said Christina Austin - CEO of Pixel Film Studios. ... customizable and all within Final Cut Pro X . Simply select a ProHand ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... 2016 According to a new ... Pen Needles, Safety Pen Needles), Needle Length (4mm, 5mm, ... Mode of Purchase (Retail, Non-Retail) - Trends & Global ... the market for the forecast period of 2016 to ... Billion by 2021 from USD 1.65 Billion in 2016, ...
(Date:6/24/2016)... Belgium , June 24, 2016 ... the appointment of Dr. Edward Futcher ... Non-Executive Director, effective June 23, 2016.Dr. Futcher was ... Nominations and Governance Committees.  As a non-executive member ... independent expertise and strategic counsel to VolitionRx in ...
(Date:6/23/2016)... , June 23, 2016  MedSource announced today ... its e-clinical software solution of choice.  This latest ... possible value to their clients by offering a ... preferred relationship establishes nowEDC as the EDC platform ... MedSource,s full-service clients.  "nowEDC has long been a ...
Breaking Medicine Technology: