Navigation Links
Valium hits 40 years old, anxiety-free

Valium, the drug that revolutionized the treatment of anxiety and became a cultural icon, is 40 years old this year.
The drug owes its success to the stubborn streak of chemist Leo Sternbach, who refused to quit after his boss at Hoffmann-La Roche ended a project to develop a tranquilizer to compete with a rival company's drug. Sternbach tested one last version and in just a day, he got the results: The compound made animals relaxed and limp.//

Sternbach had made the discovery that eventually led to Valium. It was approved for use in 1963 and became the country's most prescribed drug from 1969 to 1982. Valium also was referred to as a "doll" -- one of the pills popped by female characters in novelist Jacqueline Susann's racy 1966 best-seller "Valley of the Dolls." Most of the prescriptions were written by family doctors rather than psychiatrists, and the majority of users were women.

With Valium, Sternbach gave the company its first blockbuster. Sternbach had created an entire new class of tranquilizers named benzodiazepines, which were safer and more effective than previous treatments such as barbiturates, opiates, alcohol and herbs. Unlike earlier drugs, Valium did not slow breathing, so patients couldn't use it to commit suicide. But it was overused, Sternbach said; some patients became addicted, so a doctor's visit was required for refills.

Still, benzodiazepines remain the most prescribed anxiety drugs, partly because they start working as fast as one hour, slowing brain activity. They also are used for treating panic and phobia disorders and insomnia, calming patients before surgery and relaxing muscles. Sternbach officially retired in 1973, but worked most days until recently. He mentored young scientists, corresponded and consulted with others, and worked on his biography, due out this fall under the title, "Good Chemistry: The Life and Times of Valium Inventor Leo Sternbach." Sternbach's credits include 241 patents, 122 pu blications, honorary degrees and other awards. His other breakthroughs include the sleeping pills Dalmane and Mogadon, Klonopin for epileptic seizures and Arfonad, for limiting bleeding during brain surgery.

"He's an inventor's inventor," "Within every company, there is a person or two whose legacy becomes the hallmark of what the company is about, and for Roche, it is Dr. Sternbach."
'"/>




Related medicine news :

1. Test tube babies, 25 years later
2. Diabetes cases could double in developing countries in next 30 years
3. Larynx transplant restores patients voice after 20 years
4. New Blood Thinner Pill - First Potential Alternative to Warfarin in 50 years
5. Microbicides could serve to materialise women empowerment in the years to come
6. Diagnosis of Alzheimers years before clinical signs emerge
7. Induced abortion results in years of trauma.
8. 10 Million Indian Females Aborted In 20 years
9. Loss and damage to the brain cells possible with lead exposure in years ahead
10. Womb transplantation- to be successful in 2 years’ tim
11. Babies under two years of age to be administered Meningitis vaccination
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:2/6/2016)... (PRWEB) , ... February 06, 2016 , ... ... phases of eating disorder treatment helps to reduce the frequency and level of ... the Recovery Phase: Re-Establishing Healthy Identity and Purpose,” will explore the critical tasks ...
(Date:2/5/2016)... Toronto, Ontario (PRWEB) , ... February 05, 2016 ... ... today announced the availability of the company's lighter, sleeker next generation LYNX VR ... assembly plant. , Improvements in design and manufacturing not only reduce the ...
(Date:2/5/2016)... ... ... The event is being held on April 7, 2016 from 5:30 p.m. ... Parkinson’s will fund nearly $100,000 for research for the care and cure of Parkinson’s ... is the architect of this informative event to raise awareness and funds for Parkinson’s. ...
(Date:2/5/2016)... ... February 05, 2016 , ... Looking for a last-minute Valentine’s ... the tips of your toes. Foot massage, whether administered by a professional masseuse or ... relaxation. The American Board of Multiple Specialties in Podiatry (ABMSP) has taken ...
(Date:2/5/2016)... Florida (PRWEB) , ... February 05, 2016 , ... ... non-profit organization devoted exclusively to funding innovative lymphoma research and serving the lymphoma ... – is poised to once again host, Swirl, A Wine Tasting Event at ...
Breaking Medicine News(10 mins):
(Date:2/5/2016)... Site Profile: --> Site ... People, announced their latest primary healthcare case study where speech recognition ... and to save the practice money. Site Profile: ... Challenge: --> ,- Wirral CCG ,- VoicePower client since ... Wirral CCG ,- VoicePower client since 2013 Challenge: ...
(Date:2/5/2016)... Feb. 5, 2016 ... the "Global Obstetrics Partnering 2010-2016: Deal ... to their offering. --> http://www.researchandmarkets.com/research/hcdvg6/global_obstetrics ... "Global Obstetrics Partnering 2010-2016: Deal trends, ... their offering. --> Research and ...
(Date:2/4/2016)...  Edwards Lifesciences Corporation (NYSE: EW ), the ... and critical care monitoring, announced today that it has ... Morgan Stanley & Co. LLC to repurchase $325 million ... the Company,s previously authorized program to repurchase up to ... --> --> Under the ...
Breaking Medicine Technology: