Navigation Links
Vaginal Vaccine may prevent periodic infections

A recent study suggests that a trial vaccine, administered as a suppository inserted into the vagina, may be safe and effective in defending urinary tract infections (UTIs') in women who suffer them repeatedly. According to Dr. Johny Elkahwaji of the University of Augusta and colleagues, about half of all women will get a UTI at some point in their lifetime. Antibiotics are useful in preventing and treating UTIs, but a vaccine could prevent the overuse of antibiotics,// which can cause resistant, difficult to treat strains of bacteria to develop.

At the American Urological Association, Elkahwaji presented data on a vaccine containing 10 different types of heat-killed bacteria that frequently cause UTIs. He observed that the vaccine was previously tested in Switzerland about 10 years ago in an injection form. "But its use was discontinued because of the side effects.

To test the suppository form of the vaccine, researchers assigned 50 women to one of three treatment groups. One group received six inactive placebo treatments. Another group received six active treatments, one at the beginning of the study and then one at weeks 1, 2, 6, 10 and 14. The third group received three active and three placebo treatments over a similar time frame.

The entire group of women were followed for 4 months to record side effects and to see whether their UTIs returned. The researchers found that 30% of patients in the group receiving 5 immunizations experienced a repeat infection whereas 85% of placebo-treated women developed UTIs.

A few patients experienced "brief vaginal irritation within one day of immunization or bad transient diarrhea." The investigators conclude, "The lack of significant adverse effects in over 100 women confirms the safety of the vaccine itself and the immunization method."

According to Elkahwaji, this is the only vaginal vaccine currently being tested for recurrent UTI. According to him, they have FDA appr oval to continue the commercialization of this vaccine, and we plan to start a multicenter phase III clinical trial.


Related medicine news :

1. Vaginal Birth After C-section Dangerous For Both Mother And Baby
2. PET Scanner detects more Vaginal cancer than CT scans
3. Vaginal atrophy drug Ospemifene found effective in breast cancer Prevention
4. Increased Risk Of HIV Transmission Following Vaginal Washing
5. Risk Of AIDS Rises With Vaginal Washes
6. Vaginal massage during pregnancy avoids Episiotomy procedure
7. Vaginal Gel That Protects Against HIV To Hit The Markets By 2010
8. Vaginal Delivery Should Be an Option after Multiple Cesareans
9. New Laparoscopic Surgery to Correct Vaginal Vault Prolapse Is Effectual Than the Conventional Surgery
10. Extra Vaginal Bleed After ‘C’ Section Can be Prevented By Contraceptive Pils
11. Risk of Hemorrhage Increased in Vaginally Born Babies
Post Your Comments:

(Date:11/25/2015)... ... , ... “While riding the bus, I saw a passenger in a wheelchair ... to be a convenient and comfortable way to protect them from bad weather, so ... safely travel during cold or inclement weather. In doing so, it ensures that the ...
(Date:11/25/2015)... ... 2015 , ... Privately owned Contract Development and Manufacturing Organization ... current state of the art research, development and manufacturing facility outside of Fort ... capacity as well as to support its clients’ growing research and development and ...
(Date:11/25/2015)... ... , ... Students and parents have something to be thankful for this Thanksgiving ... awards. California Casualty is proud to support the contest designed to utilize ... driving, the number one killer of young drivers. , Almost 1,000 entries of ...
(Date:11/24/2015)... ... , ... New patients who wish to seek treatment for missing teeth can ... her Mississauga, ON practice. Dr. Williams has been providing dental service for over 34 ... Missing teeth can lead to a variety of complications if they are not replaced ...
(Date:11/24/2015)... , ... November 25, 2015 , ... ... and development solutions for drugs, biologics, consumer health and global clinical supply services, ... at the upcoming Clinical Trial Supply East Asia Conference, to be held at ...
Breaking Medicine News(10 mins):
(Date:11/24/2015)... and VANCOUVER, Nov. 24, 2015 /PRNewswire/ - ESSA Pharma Inc. ... ) announced today that the first patient has been ... as a treatment for metastatic castration-resistant prostate cancer ("mCRPC"). ... Canada.  --> the United States ... the Phase 1/2 clinical trial, ESSA intends to demonstrate ...
(Date:11/24/2015)... PUNE, India , November 24, 2015 ... new market research report "Spine Biologics Market by Product Type ... Type (Anterior Cervical Discectomy and Fusion, Posterior Lumbar Interbody Fusion), ... by MarketsandMarkets, the global market was valued at $1.90 Billion ... 2020, at a CAGR of 4.4% during the forecast period ...
(Date:11/24/2015)... India , November 24, 2015 ... . --> adds Latest Guidebook ... report of 217 pages published in November 2015 ... its online business intelligence library at ... one of the fastest growing global economies with ...
Breaking Medicine Technology: