Navigation Links
Vaginal Lubricants can Reduce Cervical Cancer Risk

Researchers have found that spermicides and vaginal lubricants control the growth of infection caused by human papillomavirus (HPV), which causes cervical cancer.

The study was conducted by a team of researchers led by John Schiller at the National Cancer Institute, Bethesda, Maryland.

The problem with doing the experiments was that HPV survive only in humans, making it difficult to form a mouse model, and also the virus does not replicate properly in cell cultures.

However, in the first stages of infection, when the virus enters the cell, it is not species specific.

As part of the study, researchers experimented on mice with early stages of HPV infection by forming an HPV 'pseudovirus' which had the same protein coat as HPV but a different genome, and could replicate in cell cultures.

The pseudovirus was also marked with a fluorescent tag, which enabled scientists to follow the growth of infection.

"The pseudovirus mimics the initial phases of infection well. No model is perfect, but we feel that ours is by far the best," Nature quoted Schiller, as saying.

Researchers then treated the model with spermicide nonoxynol-9 and vaginal lubricants.

The study found that nonoxynol-9 increased the risk of HPV infection in mouse, while vaginal lubricant carrageenan hindered the virus by stopping the infection.

Nonoxynol-9 is believed to worsen the cells in the lining of the vaginal tract that might allows the virus to cause infection by reaching the underlying membrane.

According to Lesley Walker, of Cancer Research UK in Hull, the study could help treat cervical cancer.

"It could be key in understanding the early events in the development of cervical cancer," Walker said.

The study noted that intact cells in the genital tract lining were HPV resistant and would not bind to the virus.

"The cr ucial step for infection seems to be the virus binding to the basement membrane that underlies these cells," Schiller said.


Related medicine news :

1. Vaginal Birth After C-section Dangerous For Both Mother And Baby
2. PET Scanner detects more Vaginal cancer than CT scans
3. Vaginal Vaccine may prevent periodic infections
4. Vaginal atrophy drug Ospemifene found effective in breast cancer Prevention
5. Increased Risk Of HIV Transmission Following Vaginal Washing
6. Risk Of AIDS Rises With Vaginal Washes
7. Vaginal massage during pregnancy avoids Episiotomy procedure
8. Vaginal Gel That Protects Against HIV To Hit The Markets By 2010
9. Vaginal Delivery Should Be an Option after Multiple Cesareans
10. New Laparoscopic Surgery to Correct Vaginal Vault Prolapse Is Effectual Than the Conventional Surgery
11. Extra Vaginal Bleed After ‘C’ Section Can be Prevented By Contraceptive Pils
Post Your Comments:

(Date:11/25/2015)... ... 25, 2015 , ... Wimbledon Health Partners, the industry leader ... Athletics Facebook page to educate the public, parents and school athletic departments ... people under the age of 25 die from sudden cardiac arrest every year. ...
(Date:11/25/2015)... ... November 25, 2015 , ... Smiles by Stevens is pleased ... moderate facial wrinkling. While many patients are aware of the benefits of Botox® in ... delivers to those suffering with discomfort, soreness, and pain as a result of Jaw ...
(Date:11/25/2015)... ... November 25, 2015 , ... Brillianteen, ... friendships, and learning in its 65th Anniversary Brillianteen Revue, scheduled for March 4-6, ... , For 65 years, Brillianteen has been a treasured tradition for numerous families ...
(Date:11/25/2015)... ... 2015 , ... Today, Mothers Against Drunk Driving (MADD) learned that ... for the first time since 2011. In 2014, there were 9,967 fatalities involving an ... the National Highway Traffic Safety Administration (NHTSA), 32,675 people were killed in traffic crashes ...
(Date:11/25/2015)... ... November 25, 2015 , ... "When I underwent ... bras were incredibly uncomfortable," said an inventor from Bronx, N.Y. "In order to ... the patent-pending RECOVERY BRA for added comfort and support. The bra is easier ...
Breaking Medicine News(10 mins):
(Date:11/26/2015)... , November 26, 2015 3D ... by 2022, according to a new report by Grand View ... Kidney Disease (CKD) which demands kidney transplantation is expected to ... cost effective substitute for organ transplantation. --> 3D ... by 2022, according to a new report by Grand View ...
(Date:11/26/2015)... , November 26, 2015 ... Juntendo universitetssjukhus ser potential att använda ... magnetresonansbilder (MR-bilder) för patienter med multipel ... ett forskningsavtal med SyntheticMR AB för att ... forskningsprojekt på sjukhuset. Med SyMRI kan man ...
(Date:11/26/2015)... 26, 2015 Research and Markets ( ... "2016 Future Horizons and Growth Strategies in ... Shares, Country Segment Forecasts, Competitive Intelligence, Emerging Opportunities" ... --> --> This new ... Italian therapeutic drug monitoring market, including emerging tests, ...
Breaking Medicine Technology: