Navigation Links
Vaginal Lubricants can Reduce Cervical Cancer Risk

Researchers have found that spermicides and vaginal lubricants control the growth of infection caused by human papillomavirus (HPV), which causes cervical cancer.

The study was conducted by a team of researchers led by John Schiller at the National Cancer Institute, Bethesda, Maryland.

The problem with doing the experiments was that HPV survive only in humans, making it difficult to form a mouse model, and also the virus does not replicate properly in cell cultures.

However, in the first stages of infection, when the virus enters the cell, it is not species specific.

As part of the study, researchers experimented on mice with early stages of HPV infection by forming an HPV 'pseudovirus' which had the same protein coat as HPV but a different genome, and could replicate in cell cultures.

The pseudovirus was also marked with a fluorescent tag, which enabled scientists to follow the growth of infection.

"The pseudovirus mimics the initial phases of infection well. No model is perfect, but we feel that ours is by far the best," Nature quoted Schiller, as saying.

Researchers then treated the model with spermicide nonoxynol-9 and vaginal lubricants.

The study found that nonoxynol-9 increased the risk of HPV infection in mouse, while vaginal lubricant carrageenan hindered the virus by stopping the infection.

Nonoxynol-9 is believed to worsen the cells in the lining of the vaginal tract that might allows the virus to cause infection by reaching the underlying membrane.

According to Lesley Walker, of Cancer Research UK in Hull, the study could help treat cervical cancer.

"It could be key in understanding the early events in the development of cervical cancer," Walker said.

The study noted that intact cells in the genital tract lining were HPV resistant and would not bind to the virus.

"The cr ucial step for infection seems to be the virus binding to the basement membrane that underlies these cells," Schiller said.


'"/>




Related medicine news :

1. Vaginal Birth After C-section Dangerous For Both Mother And Baby
2. PET Scanner detects more Vaginal cancer than CT scans
3. Vaginal Vaccine may prevent periodic infections
4. Vaginal atrophy drug Ospemifene found effective in breast cancer Prevention
5. Increased Risk Of HIV Transmission Following Vaginal Washing
6. Risk Of AIDS Rises With Vaginal Washes
7. Vaginal massage during pregnancy avoids Episiotomy procedure
8. Vaginal Gel That Protects Against HIV To Hit The Markets By 2010
9. Vaginal Delivery Should Be an Option after Multiple Cesareans
10. New Laparoscopic Surgery to Correct Vaginal Vault Prolapse Is Effectual Than the Conventional Surgery
11. Extra Vaginal Bleed After ‘C’ Section Can be Prevented By Contraceptive Pils
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/25/2016)... , ... June 25, 2016 , ... "With 30 hand-drawn ... specific project," said Christina Austin - CEO of Pixel Film Studios. , ProHand ... all within Final Cut Pro X . Simply select a ProHand generator and ...
(Date:6/25/2016)... ... June 25, 2016 , ... On Friday, June 10, Van Mitchell, ... at Work award to iHire in recognition of their exemplary accomplishments in worksite health ... annual Maryland Workplace Health & Wellness Symposium at the BWI Marriott in Linthicum Heights. ...
(Date:6/24/2016)... ... June 24, 2016 , ... June 19, 2016 is World Sickle Cell ... pain and the benefits of holistic treatments, Serenity Recovery Center of Marne, ... Cell Disease. , Sickle Cell Disease (SCD) is a disorder of the red blood ...
(Date:6/24/2016)... (PRWEB) , ... June 24, 2016 , ... ... now offering micro-osteoperforation for accelerated orthodontic treatment. Dr. Cheng has extensive experience with ... Damon brackets , AcceleDent, and accelerated osteogenic orthodontics. , Micro-osteoperforation is a ...
(Date:6/24/2016)... ... 2016 , ... EB Medicine presented its first-ever “Issue of ... in Ponte Vedra Beach, FL. The awards honor the outstanding work of leading ... and Pediatric Emergency Medicine Practice. , “With this award, we recognize the efforts ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... , June 23, 2016 Bracket , a ... its next generation clinical outcomes platform, Bracket eCOA (SM) ... on June 26 – 30, 2016 in Philadelphia ... electronic Clinical Outcome Assessment product of its kind to fully ... Bracket eCOA 6.0 is a flexible platform for ...
(Date:6/23/2016)... and INDIANAPOLIS , June ... receiving a Lilly Diabetes Tomorrow,s Leaders Scholarship is any ... scholarship winners, announced today online at www.diabetesscholars.org ... type 1 diabetes stand in the way of academic ... supported the Foundation,s scholarship program since 2012, and continues ...
(Date:6/23/2016)... June 23, 2016 Revolutionary technology ... Oticon , industry leaders in advanced audiology and ... Oticon Opn ™, the world,s first internet connected ... for IoT devices.      (Photo: http://photos.prnewswire.com/prnh/20160622/382240 ... a number of ,world firsts,: , TwinLink™ ...
Breaking Medicine Technology: