Navigation Links
Vaccine may overcome Common Infections: Researchers

Staphylococcus aureus infections may soon be overcome by a newly developed vaccine according to U.S. researchers on Tuesday.//

The team, receiving funds from the government, said that their vaccine worked against several different strains of the Staphylococcus aureus, in mice. This bacteria causes a range of potentially fatal infections and has become resistant to many antibiotics.

Most hospital-acquired infections are commonly caused by it, causing inflammation of the heart or endocarditis, severe lung infections, toxic-shock syndrome and food poisoning.

In US hospitals around 90,000 people die each year from hospital acquired infections costing about $4.5 billion, according to the U.S. Centers for Disease Control and Prevention. 80 percent of these hospital infections are caused by Staph aureus.

With most strains having developed resistance to antibiotics, these infections are often difficult and sometimes even impossible to treat.

Dr. Olaf Schneewind of the University of Chicago, who led the study, said, "One by one, this organism has learned how to evade nearly all of our current antibiotics. So, generating protective immunity against invasive S. aureus has become an important goal."

According to the CDC in 1972, only 2 percent of Staphylococcus aureus bacteria infections were drug-resistant but in 2004, 63 percent were.

Schneewind's team has created a vaccine that combines four of the proteins that make up Staphylococcus aureus.

Reporting their findings in the Proceedings of the National Academy of Sciences, the research team said that they tested 19 different proteins found in Staph bacteria, and chose the four that stimulated the most immune response in the mice.

Schneewind said, "When we challenged the immunized mice by exposing them to a human strain of S. aureus, the combination vaccine provided complete protection, whereas the control group developed bacterial abscesse s."

On testing the mice with five different S. aureus strains that infect humans it was found that the vaccine offered significant protection against all strains.

Dr. Anthony Fauci, director of the National Institute of Allergy and Infectious Diseases, which paid for the study, "This finding represents a promising step toward identifying potential components to combine into a vaccine designed for people at high risk of invasive S. aureus infection."

This kind of approach is known as rational drug design. While most vaccines use a whole virus or bacterium that has been crippled or killed and injected into the body to help stimulate immune system recognition this approach has not worked against Staph aureus.


Related medicine news :

1. Vaccine to quit smoking?
2. First Vaccine Designed for Africa Cleared for Testing in Humans
3. Vaccine for Alzheimer’s diseas
4. Health Officials Recommend Flu Vaccine
5. Smallpox Vaccine May Help Fight Cervical Cancer
6. Panacea Biotech To Market Anthrax Vaccine
7. New Prostate Cancer Vaccine Shows Promise
8. Drug Firm Offers to Donate Smallpox Vaccine
9. Vaccine guards against shingles
10. Vaccine for septic conditions
11. A new Vaccine for Pneumonia
Post Your Comments:

(Date:10/13/2017)... ... , ... The American Board of Family Medicine's (ABFM) Board of Directors has ... succeeding Dr. James C. Puffer upon his retirement. Dr. Newton will serve in the ... at the end of 2018. Upon assuming the role of President and CEO on ...
(Date:10/13/2017)... QUEENS, N.Y (PRWEB) , ... October 13, 2017 , ... ... recently became a member of ElderCounsel, a national organization of elder law and special ... constantly changing laws and rules. It also provides a forum to network with elder ...
(Date:10/13/2017)... ... ... Ellevate Network, the leading network for professional women, brought together some of ... their inaugural Summit in New York City in June. The event was livestreamed with ... 3 million. To watch the Mobilize Women video, click here . , ...
(Date:10/13/2017)... VA (PRWEB) , ... October 13, 2017 , ... ... of DevOps and Agile Software Development, has been awarded a contract by the ... Blanket Purchase Agreement (BPA) aims to accelerate the enterprise use of Agile methodologies ...
(Date:10/12/2017)... CA (PRWEB) , ... October 12, 2017 , ... ... Cheng, are now treating sleep apnea using cutting-edge Oventus O2Vent technology. ... a serious sleep disorder characterized by frequent cessation in breathing. Oral appliances can ...
Breaking Medicine News(10 mins):
(Date:10/12/2017)... EXTON, Pa. , Oct. 12, 2017 ... global leader in innovative solutions for injectable drug administration, ... results before the market opens on Thursday, October 26, ... discuss the results and business expectations at 9:00 a.m. ... 877-930-8295 (U.S.) or 253-336-8738 (International). The conference ID is ...
(Date:10/10/2017)... received FDA 510(k) clearance in May 2017 for its highly anticipated ... for endoscopy environments. An innovative secondary monitor solution, ZeroWire Mobile ... the improvement of patient outcomes, procedural efficiency, and the lowering of ... ... By ...
(Date:10/4/2017)... Centers for Disease Control and Prevention (CDC), influenza vaccination should take ... communities across Massachusetts , Connecticut , ... through the end of the month. *Some exclusions apply ... ... by the end of October, according to the Centers for Disease Control ...
Breaking Medicine Technology: