Navigation Links
Vaccine may overcome Common Infections: Researchers

Staphylococcus aureus infections may soon be overcome by a newly developed vaccine according to U.S. researchers on Tuesday.//

The team, receiving funds from the government, said that their vaccine worked against several different strains of the Staphylococcus aureus, in mice. This bacteria causes a range of potentially fatal infections and has become resistant to many antibiotics.

Most hospital-acquired infections are commonly caused by it, causing inflammation of the heart or endocarditis, severe lung infections, toxic-shock syndrome and food poisoning.

In US hospitals around 90,000 people die each year from hospital acquired infections costing about $4.5 billion, according to the U.S. Centers for Disease Control and Prevention. 80 percent of these hospital infections are caused by Staph aureus.

With most strains having developed resistance to antibiotics, these infections are often difficult and sometimes even impossible to treat.

Dr. Olaf Schneewind of the University of Chicago, who led the study, said, "One by one, this organism has learned how to evade nearly all of our current antibiotics. So, generating protective immunity against invasive S. aureus has become an important goal."

According to the CDC in 1972, only 2 percent of Staphylococcus aureus bacteria infections were drug-resistant but in 2004, 63 percent were.

Schneewind's team has created a vaccine that combines four of the proteins that make up Staphylococcus aureus.

Reporting their findings in the Proceedings of the National Academy of Sciences, the research team said that they tested 19 different proteins found in Staph bacteria, and chose the four that stimulated the most immune response in the mice.

Schneewind said, "When we challenged the immunized mice by exposing them to a human strain of S. aureus, the combination vaccine provided complete protection, whereas the control group developed bacterial abscesse s."

On testing the mice with five different S. aureus strains that infect humans it was found that the vaccine offered significant protection against all strains.

Dr. Anthony Fauci, director of the National Institute of Allergy and Infectious Diseases, which paid for the study, "This finding represents a promising step toward identifying potential components to combine into a vaccine designed for people at high risk of invasive S. aureus infection."

This kind of approach is known as rational drug design. While most vaccines use a whole virus or bacterium that has been crippled or killed and injected into the body to help stimulate immune system recognition this approach has not worked against Staph aureus.


Related medicine news :

1. Vaccine to quit smoking?
2. First Vaccine Designed for Africa Cleared for Testing in Humans
3. Vaccine for Alzheimer’s diseas
4. Health Officials Recommend Flu Vaccine
5. Smallpox Vaccine May Help Fight Cervical Cancer
6. Panacea Biotech To Market Anthrax Vaccine
7. New Prostate Cancer Vaccine Shows Promise
8. Drug Firm Offers to Donate Smallpox Vaccine
9. Vaccine guards against shingles
10. Vaccine for septic conditions
11. A new Vaccine for Pneumonia
Post Your Comments:

(Date:11/24/2015)... ... November 25, 2015 , ... Genesis Chiropractic Software helps ... creates an agreement between the practice owner and the patient that automatically manages ... and projections. Click here to learn more. , According ...
(Date:11/24/2015)... ... 2015 , ... New patients who wish to seek treatment for missing teeth ... at her Mississauga, ON practice. Dr. Williams has been providing dental service for over ... , Missing teeth can lead to a variety of complications if they are not ...
(Date:11/24/2015)... ... November 24, 2015 , ... ThirdLove, the fast-growing ... a week early, offering 40% off select bras and underwear styles, now through ... both mobile fit technology and the latest fashion, quickly becoming the next generation ...
(Date:11/24/2015)... ... November 24, 2015 , ... DMG Productions announced that they will feature ... quarter 2016 via Discovery Channel. Dates and show times TBA. , Aphria, Inc., is ... the business of producing and supplying medical marijuana pursuant to the Marijuana for Medical ...
(Date:11/24/2015)... Lake City, UT (PRWEB) , ... November 24, 2015 , ... ... to Forbes Magazine. For a business, it is critical that the first impression be ... a business, they are not likely to buy anything or want to return. They ...
Breaking Medicine News(10 mins):
(Date:11/25/2015)... , Nov. 25, 2015 On Tuesday, ... federal bellwether trial against Wright Medical Technology, Inc. ... their Conserve metal-on-metal hip implant device, awarded $11 ... a two week trial and three days of ... hip device was defectively designed and unreasonably dangerous, ...
(Date:11/25/2015)...  ARKRAY USA , Inc., a ... demonstrating the accuracy of its blood glucose meter systems. ... Diabetes and Cardiovascular Disease in Los Angeles ... ® 01 meter and the Assure ® ... to accurately measure glucose levels in blood is essential ...
(Date:11/25/2015)... MELVILLE, N.Y. , Nov. 25, 2015  Henry ... products and services to office-based dental, medical and animal ... Dental (GNYDM) Meeting the Henry Schein ConnectDental® Pavilion ... industry,s broadest array of open solutions designed to help ... Click here for a schedule of ...
Breaking Medicine Technology: