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VBI Provides Potential Targets to Diabetes Therapeutics

opher L. Case, Edward M. Concar, Kristin L. Boswell, and Biswarup Mukhopadhyay, in issue 281(51): 39 262–39 272 (www.jbc.org/).

Case, Concar, and Boswell were all undergraduate students when they carried out the research. Case and Boswell were Virginia Tech biochemistry undergraduates who worked in Mukhopadhyay's research group at VBI, while Concar was a microbiology undergraduate at the University of Illinois at Urbana-Champaign, where Mukhopadhyay worked as a postdoctoral researcher. Concar now works in the biochemistry department of Genencor Inc. Boswell is currently a biochemistry graduate student at the University of Wisconsin.

Case, now a graduate student at Yale University, remarks: "I am better prepared to learn new techniques, plan experiments, and write scientific papers--three very important aspects of graduate and post-graduate research."

Mukhopadhyay commented: "The undergraduates made major contributions to the work, cloning, modifying, purifying and characterizing the enzyme, as well as performing kinetic experiments, secondary structure studies, and structural modeling."

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