Navigation Links
Using Multivitamins Before And After Conception Averts Preeclampsia

Women who are considering becoming pregnant could prevent preeclampsia if they started a course of multivitamins three months before conception and following it up// during the first three months of their pregnancy. Preeclampsia is a condition where the woman’s blood pressure shoots up dangerously and could prove lethal for both mother and child. Researchers at the University of Pittsburgh say that this condition could be avoided by taking multivitamins. The study is to be published in the Sept. 1 print issue of the American Journal of Epidemiology

Overall, women who used multivitamins regularly showed a 45 percent reduction in preeclampsia risk, according to the study. However, results were even more remarkable for women who were not overweight prior to pregnancy.

"Our data show that women who are not overweight before pregnancy and who used multivitamins at least once a week before conception and in the first three months of pregnancy reduced their risk of preeclampsia by a striking 72 percent compared to those who didn't take a multivitamin during this time period," said Lisa Bodnar, Ph.D., M.P.H., R.D., assistant professor of epidemiology at the University of Pittsburgh Graduate School of Public Health (GSPH). "At this time, multivitamin use makes little apparent difference in preeclampsia rates for women who are overweight before pregnancy. Even so, the results suggest that regular multivitamin use in the pre-pregnancy period may help to prevent preeclampsia."

Also known as toxemia, preeclampsia affects about 7 percent of first pregnancies and is a leading cause of premature delivery and maternal and fetal death. Signs of preeclampsia include high blood pressure, protein in the urine and swelling of the hands and feet. Untreated, the condition may progress to the far more serious eclampsia, which can lead to seizures, coma and death.

Preeclampsia is more prevalent in the developing world, where it accounts for up to 80 percent of maternal deaths. And while treatment is more readily available in developed countries, preeclampsia remains the leading cause of maternal death. Infants born to mothers with preeclampsia have a risk of mortality five times greater than those born to women with normal pregnancies. In the United States alone, nearly 15 percent of preterm deliveries are a result of preeclampsia.

Dr. Bodnar and her colleagues evaluated data from 1,835 women who were enrolled in the University of Pittsburgh's Pregnancy Exposures and Preeclampsia Prevention Study between 1997 and 2001. Overall, the prevalence of preeclampsia was 4.4 percent for non-multivitamin users and 3.8 percent for those who used multivitamins, with the most significant differences being noted among women who had a body mass index (a common body weight measure) of less than 25. Most authorities define overweight at a BMI of 25 and obesity as a BMI of 30 or above.

Because multivitamins contain many nutrients, it is difficult to know the exact mechanism by which the risk of preeclampsia is reduced, noted Dr. Bodnar, who also is an assistant investigator at the university-affiliated Magee-Womens Research Institute (MWRI). Other recent studies have shown limited benefits – and some risk – associated with large doses of vitamins C and E in women at high risk of preeclampsia. "However, the study does show further evidence that nutrition is relevant for the prevention of preeclampsia," she said.

Although Dr. Bodnar and her colleagues tried to adjust for possible complicating factors such as smoking, exercise habits, fruit- and vegetable-intake, demographic and other socioeconomic factors, it is possible that the study findings could be attributed to other differences among multivitamin supplement users and nonusers that investigators did not identify. In addition, the analysis depended on self-reporting of multivitamin use rather than a random assignment of supplement use . Even so, the association between multivitamin use and diminished risk of preeclampsia strongly continues inasmuch as adjustments are possible.

"Preeclampsia is a potentially devastating condition for mother and baby," observed James M. Roberts, M.D., director of the Magee-Womens Research Institute and senior author of the paper. "It may be that taking a multivitamin prior to conception positively influences embryonic implantation, which is a physiologic process known to be abnormal in preeclampsia. More study is needed to clarify these findings."

Researchers are unsure of the reasons why multivitamin use appears to have no benefit to preeclampsia risk in overweight women, Dr. Bodnar said. "It may be that typical multivitamins, which contain low nutrient doses, may not be adequate to overcome the metabolic challenges associated with the development of preeclampsia along with being overweight and pregnant," she added. "But again, more study is needed to test these ideas."

Contact: Michele Baum
baummd@upmc.edu
412-647-3555
University of Pittsburgh Medical Center
Source: Eurekaler
'"/>




Related medicine news :

1. Preventing Strokes Using Less Invasive Techniques
2. Using Cholesterol Lowering Drugs Effectively
3. Using herbal remedies with chemotherapy may not be a good idea
4. Teenagers Using Hormones And Dietary Supplements To Good Physique
5. Using Stem Cells To Treat Incontinence In Women
6. Using Eyes As The Line Of Reference For Fetal Brain Imaging
7. Remote Robotic Surgery Using Miniature Robots
8. Driving While Using A Mobile Phone May Be Dangerous
9. Detecting Brain Abnormalities in Babies Using New Brain Scanners.
10. Mobilizing Stem Cells at the Injured Site Using Hyperbaric Oxygen Treatments.
11. Treatment of Sickle Cell Anemia Using Gene Therapy.
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:2/9/2016)... ... February 09, 2016 , ... ... LLC to help enterprises move workloads to the cloud. Cirracore provides a ... their cloud without traversing the Internet. Transformation Solutions (TSL Partners) provides a ...
(Date:2/9/2016)... ... February 09, 2016 , ... On January 12, 2016 ... an appointment after they noticed their furnace not producing any heat. Shortly after entering ... The cracked heat exchanger was leaking dangerous levels of carbon monoxide into the home, ...
(Date:2/9/2016)... ... February 09, 2016 , ... ... service to expand access to affordable hearing aids , increase industry transparency, ... individuals in the United States. , “For the average consumer, the hearing aid ...
(Date:2/9/2016)... ... February 09, 2016 , ... United Methodist Communications collaborated ... Prevention,” an animated video designed to prevent the next widespread Ebola ... video are being distributed throughout Togo, Liberia, Sierra Leone, Nigeria, Côte d’Ivoire and ...
(Date:2/9/2016)... ... February 09, 2016 , ... The Brain Preservation Foundation’s (BPF) ... from 21st Century Medicine (21CM) ( http://www.21cm.com/ ), spearheaded by recent MIT ... of an intact rabbit brain for extremely long-term storage using a combination of ...
Breaking Medicine News(10 mins):
(Date:2/9/2016)... 9, 2016 Mast Therapeutics, Inc. (NYSE ... sickle cell disease and heart failure, today announced that it ... purchase common stock in an underwritten public offering.  The offering ... be no assurance as to whether or when the offering ... terms of the offering.   --> ...
(Date:2/9/2016)... Feb. 9, 2016 The new report "Global Diagnostic Ultrasound ... & Consulting group reveals that global diagnostic ultrasound devices market was ... to US$ 7,466.3 million by 2019 at a CAGR of 6.8% ... global ultrasound market has been analyzed for six geographies of ... Asia-Pacific , Latin America , ...
(Date:2/9/2016)... , Feb. 9, 2016 The leader ... that AcceleDent ® is the recipient of the ... category. An FDA-cleared, Class II medical device that speeds ... percent and relieves pain often associated with treatment, AcceleDent ... participated in the annual Orthotown survey of ...
Breaking Medicine Technology: