Navigation Links
Use of a fast-acting insulin analog to control diabetic ketoacidosis in Children

Diabetic ketoacidosis (DKA) is a life-threatening condition that frequently requires hospitalization in children with type 1 diabetes.// The critical factors in the treatment of DKA include careful and frequent monitoring of the patient, skillful fluid and electrolyte adjustment, and the initiation of insulin therapy after the initial restoration of fluid volume has been achieved. Continuous low-dosage intravenous infusion of soluble insulin has been the procedure of choice for this because it provides direct control and results in a predictable rate of fall in serum glucose levels. However, admission to an intensive care unit to receive intravenous insulin infusion increases health care costs.

A recent study proposes using a subcutaneous fast-acting analog of human insulin instead of intravenous continuous regular insulin to avoid the need for a second intravenous line, simplify treatment of DKA in children, and provide a more economical solution. The aim of the study was to compare the efficacy of a subcutaneous fast-acting analog (lispro) with continuous intravenous regular insulin (CIRI) in the treatment of pediatric DKA.

The fluid replacement protocol aimed at correcting intravascular volume up to the normalization of the peripheral perfusion. Once cardiovascular stability was achieved, the child was alert, and vomiting has stopped, oral rehydration was started. Cerebral edema, the most feared complication of DKA, did not develop in the patients during this study. Also, there were no deaths or "near death" episodes, and no patient had to be treated with mannitol.

The study, published in the August issue of Diabetes Care concludes that DKA treatment with a subcutaneous fast-acting insulin analog represents a cost-effective and technically simplified procedure that precludes intensive care unit admission.


'"/>




Page: 1

Related medicine news :

1. Animal insulin product to be discontinued by drug major Eli Lilly
2. Brain stem cells to help in producing insulin
3. Now insulin can be inhaled
4. Exubera could mean the end of an insulin injection era for diabetics
5. Islet cells producing insulin cultivated in the lab
6. Pfizer vouches safety of long-term inhaled insulin.
7. Uncontrolled blood pressure
8. FDAs control is inherently weak
9. Drugs control and industry departments to share a common e-platform
10. Self control makes stress response easy
11. Progression of Glaucoma could be controlled with early detection
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:9/25/2017)... ... 25, 2017 , ... Ron Norman, CEO of Team Decades, ... executives speaking at a business luncheon today, "It is tantamount to forgetting about ... to be fully realized and activated by the corporations that recognize their worth," ...
(Date:9/25/2017)... ... September 25, 2017 , ... “The Ministry of Reconciliation: ... look at the religious stand in the sensitive matter of sexual discrimination, and ... Ministry of Reconciliation: A Compassionate and Realistic Approach to Evangelizing the LGBTQ Community” ...
(Date:9/25/2017)... York, NY and Los Angeles, CA (PRWEB) , ... September 25, ... ... has announced the opening of a full-time office in downtown Los Angeles, to service ... Arizona, Nevada and the surrounding areas. , “We are seeing an ever-increasing amount of ...
(Date:9/24/2017)... ... September 25, 2017 , ... Andrea Purcell, NMD, had an epiphany one evening. Four months pregnant, ... dinner plate. She thought pregnancy was so hard. She wondered why no one talks about ... her. In that moment, she decided to write what she wished her friends and colleagues ...
(Date:9/24/2017)... ... September 24, 2017 , ... “The Messiah 8 with ... biblical texts to firsthand experiences. “The Messiah 8 with the 3rd Anti Christ” is ... hard I’ve tried to look at all the angles of life,” Velazquez states, “I ...
Breaking Medicine News(10 mins):
(Date:9/12/2017)... -- Consumer reviews on the independent review site Consumer Affairs ... for hearing aids, ranking it higher than Miracle Ear ™, ... ... Hearing Aids ... store that provides high performance, state-of-the-art, German-engineered hearing aids directly to ...
(Date:9/7/2017)... -- Eli Lilly and Company (NYSE: LLY ... more efficiently focus resources on developing new medicines ... reductions, including those from a U.S. voluntary early ... positions. With the streamlining efforts ... $500 million that will begin to be realized ...
(Date:9/7/2017)... , Sept. 7, 2017   BioLife Solutions , ... and marketer of proprietary clinical grade cell and tissue ... announces that Mike Rice , President and CEO, will ... Rodman & Renshaw 19 th Annual ... Eastern time (12:25 p.m. Pacific time). The conference is being ...
Breaking Medicine Technology: