Navigation Links
Use of Anti-Depressant Does not Help Patients with Anorexia Nervosa

CHICAGO - Use of the anti-depressant fluoxetine did not help patients with anorexia nervosa who had restored their body weight maintain// that weight or reduce their risk of relapse, according to a study in the June 14 issue of JAMA.

Anorexia nervosa is an eating disorder primarily affecting young women and marked by an extreme fear of becoming overweight that leads to excessive dieting to the point of serious ill-health and sometimes death. It is a serious psychiatric illness with a lifetime death rate arguably as high as that associated with any psychiatric illness, according to background information in the article. A major contributor to the poor prognosis of this illness is the high rate of relapse, with 30 to 50 percent of patients requiring rehospitalization within 1 year of discharge after successful weight restoration. This has prompted interest in interventions aimed at preventing relapse following weight restoration. A substantial number of patients with anorexia nervosa receive antidepressant medications. Fluoxetine was initially marketed under the brand name of Prozac.

B. Timothy Walsh, M.D., of New York State Psychiatric Institute/Columbia University Medical Center, New York, and colleagues compared fluoxetine with placebo to determine the rate of relapse and behavioral recovery following initial treatment for anorexia nervosa. The trial included 93 patients with anorexia nervosa who had received intensive inpatient or day-program treatment and regained weight to a minimum body mass index (BMI) of 19.0. Participants were then randomly assigned to receive fluoxetine (n = 49) or placebo (n = 44) and were treated for up to 1 year as outpatients.

The researchers found that similar percentages of patients assigned to fluoxetine and to placebo maintained a BMI of at least 18.5 and remained in the study for 52 weeks (fluoxetine: 26.5 percent; placebo: 31.5 percent). The most conservative analysis of time-to-relapse found no sign ificant difference between the fluoxetine and placebo groups in time-to-relapse. At 52 weeks, 45 percent of the placebo group and 43 percent of the fluoxetine group had not relapsed.

"The current study has implications for both clinical practice and research. The present findings, coupled with those of previously published studies, indicate that the common practice of prescribing antidepressant medication is unlikely to provide substantial benefit for most patients with anorexia nervosa, either when they are underweight or immediately upon weight restoration. These data imply that therapeutic efforts would be better devoted to psychological and behavioral interventions for which there is some, albeit modest, evidence of efficacy," the authors write. "Future research on the utility of novel psychological treatments and innovative psychotropic and nonpsychotropic medications is obviously needed."


'"/>




Related medicine news :

1. Skeleton May Sustain Damage Due To Use Of Anti-Depressants
2. Risk Of Birth Defects Increased Due To Anti-Depressant Medication
3. Low Doses of Anti-Depressant May Help PMS
4. One in Three Heart Attack Patients Have No Chest Pains
5. Amphetamines Help Recovery of Stroke Patients
6. Painkillers Do Not Shorten Dying Patients Lives
7. Patients With Filariasis More Prone To HIV Infection
8. Glivec - New Hope For CMC Patients
9. Patients often assume wrongly that they are allergic to penicillin
10. New FDA Approved Drug NATRECOR For Heart Failure Patients
11. Hemochromatosis Patients Blood is Safe
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:5/27/2017)... ... ... In any business, follow up is critical to success. It is the ... treatment, there will always be some patients who can’t or won’t make a immediate ... when it comes to presenting treatment. After the patient leaves, most practices end ...
(Date:5/26/2017)... NEW YORK, NY (PRWEB) , ... May 26, ... ... Advisory Board (SAB) met this week to review more than eighty-nine grant ... both experienced and emerging young scientists in the Parkinson’s field.     , The American ...
(Date:5/26/2017)... ... May 26, 2017 , ... Somnoware, a leading ... sleep monitor with its Somnoware Sleep Device Interface (SDI). Somnoware SDI is a ... operations. With this platform, initializing devices and importing studies are just one-click operations. ...
(Date:5/26/2017)... ... ... On May 24, the Congressional Budget Office (CBO) projected that the amended ... would result in 23 million Americans losing their health insurance by 2026 as compared ... Affordable Care Act (ACA). , “It is clear from the CBO analysis that ...
(Date:5/26/2017)... ... ... Lowe acts as host and helps educate and inform the public using the “Informed” ... reconnect with America as it explores some of the best places to hike and ... inventive new place for a family vacation, and have discovered hiking. Many will agree ...
Breaking Medicine News(10 mins):
(Date:5/9/2017)... WARSAW, Ind. , May 9, 2017 ... global leader in musculoskeletal healthcare, today announced it has ... Large Employers of 2017" list. The Company was ranked ... categories of Large Employers and Healthcare Equipment and Services. ... U.S. employers based on an anonymous, independent survey of ...
(Date:5/8/2017)... 8, 2017  Diplomat Pharmacy, Inc. (NYSE: DPLO)., has ... ("WRB"), a health care service center company based in ... specializes in relationship management programs for leading pharmaceutical manufacturers ... WRB will join Envoy Health Management, ... for manufacturers, biotech firms, and other service companies. Together, ...
(Date:5/4/2017)... May 4, 2017  A recent study published ... Ultraviolet-C light as a means of disinfection ... to reduce bioburden on anesthesia workstations. In the ... high-touch, complex medical equipment surfaces contaminated with three ... "This study further validates the body of ...
Breaking Medicine Technology: