Navigation Links
Use of Anti-Depressant Does not Help Patients with Anorexia Nervosa

CHICAGO - Use of the anti-depressant fluoxetine did not help patients with anorexia nervosa who had restored their body weight maintain// that weight or reduce their risk of relapse, according to a study in the June 14 issue of JAMA.

Anorexia nervosa is an eating disorder primarily affecting young women and marked by an extreme fear of becoming overweight that leads to excessive dieting to the point of serious ill-health and sometimes death. It is a serious psychiatric illness with a lifetime death rate arguably as high as that associated with any psychiatric illness, according to background information in the article. A major contributor to the poor prognosis of this illness is the high rate of relapse, with 30 to 50 percent of patients requiring rehospitalization within 1 year of discharge after successful weight restoration. This has prompted interest in interventions aimed at preventing relapse following weight restoration. A substantial number of patients with anorexia nervosa receive antidepressant medications. Fluoxetine was initially marketed under the brand name of Prozac.

B. Timothy Walsh, M.D., of New York State Psychiatric Institute/Columbia University Medical Center, New York, and colleagues compared fluoxetine with placebo to determine the rate of relapse and behavioral recovery following initial treatment for anorexia nervosa. The trial included 93 patients with anorexia nervosa who had received intensive inpatient or day-program treatment and regained weight to a minimum body mass index (BMI) of 19.0. Participants were then randomly assigned to receive fluoxetine (n = 49) or placebo (n = 44) and were treated for up to 1 year as outpatients.

The researchers found that similar percentages of patients assigned to fluoxetine and to placebo maintained a BMI of at least 18.5 and remained in the study for 52 weeks (fluoxetine: 26.5 percent; placebo: 31.5 percent). The most conservative analysis of time-to-relapse found no sign ificant difference between the fluoxetine and placebo groups in time-to-relapse. At 52 weeks, 45 percent of the placebo group and 43 percent of the fluoxetine group had not relapsed.

"The current study has implications for both clinical practice and research. The present findings, coupled with those of previously published studies, indicate that the common practice of prescribing antidepressant medication is unlikely to provide substantial benefit for most patients with anorexia nervosa, either when they are underweight or immediately upon weight restoration. These data imply that therapeutic efforts would be better devoted to psychological and behavioral interventions for which there is some, albeit modest, evidence of efficacy," the authors write. "Future research on the utility of novel psychological treatments and innovative psychotropic and nonpsychotropic medications is obviously needed."


'"/>




Related medicine news :

1. Skeleton May Sustain Damage Due To Use Of Anti-Depressants
2. Risk Of Birth Defects Increased Due To Anti-Depressant Medication
3. Low Doses of Anti-Depressant May Help PMS
4. One in Three Heart Attack Patients Have No Chest Pains
5. Amphetamines Help Recovery of Stroke Patients
6. Painkillers Do Not Shorten Dying Patients Lives
7. Patients With Filariasis More Prone To HIV Infection
8. Glivec - New Hope For CMC Patients
9. Patients often assume wrongly that they are allergic to penicillin
10. New FDA Approved Drug NATRECOR For Heart Failure Patients
11. Hemochromatosis Patients Blood is Safe
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:7/20/2017)... ... 19, 2017 , ... Adolfson & Peterson Construction (AP) continues ... As a leader in healthcare construction, AP has successfully built several well-known medical ... Midwest with Josh now on board. , Josh brings over nine years ...
(Date:7/18/2017)... ... July 18, 2017 , ... CannaKids, a California Cooperative Cooperation that specializes in ... at the WORLDZ Summit, taking place in Hollywood from July 31-August 1, the ... medical cannabis for both pediatric and adult patients, and how the path has led ...
(Date:7/18/2017)... ... ... An inventor from Anacortes, Wash., knows the difficulties and indignity of not being ... I suffer from anxiety and vertigo on top of that," she said, "so I ... meets that need. , This device enables a woman in menopause to cool off ...
(Date:7/17/2017)... , ... July 17, 2017 , ... ... Depression and Its Treatments during Pregnancy , studies take a closer look at ... on a developing baby with one study showing newer medications may be safer ...
(Date:7/17/2017)... (PRWEB) , ... July 17, 2017 , ... ... medical education events, today announced a partnership with the Texas Academy of ... meeting will take place October 20-22, 2017 at the Hyatt Regency Dallas in ...
Breaking Medicine News(10 mins):
(Date:7/13/2017)... FREMONT, Calif. , July 13, 2017 RK ... (CA) Board of Pharmacy certification for its Fremont, ... chain support solutions in the Tri-Valley and San ... The City of Fremont , with its ... Logistics Group to provide such a powerful resource to the ...
(Date:7/11/2017)... N.J. , July 11, 2017  Bayer has awarded ... eight countries as part of its prestigious Bayer Hemophilia Awards ... Hospital of Philadelphia and Uniformed Services ... are among the winners. Grant recipients were announced last ... and Hemostasis (ISTH) 2017 Congress, Berlin, Germany ...
(Date:7/10/2017)... 10, 2017  US medical equipment and supply demand ... to Medical Equipment & Supplies: United States ... Reports. Continued increases in demand for medical services – ... population and supported by gains in disposable personal income ... New product introductions will also drive sales as providers ...
Breaking Medicine Technology: