Navigation Links
Unravelling the secrets of ‘Huntingtin’ Protein - towards the treatment of Huntingtins’ Disese

Huntingtons disease is an inherited disease of the nervous system due to the progressive gradual deterioration of the same, initially causing symptoms such as involuntary movements and balance problems and later on leading to declination of functions of speech as well.

All these days, until now, it was thought that this disease is due to a mutated form of the protein 'huntingtin' which is responsible for destroying the brain tissue.

Researchers have believed the mutation somehow caused the protein to be toxic. But until now, they have not been able to identify the function of the "normal" huntingtin protein present in people without the disease.

Researchers have uncovered the function of a protein that plays an important role in Huntington's disease (HD). Dr. Elena Cattaneo, from the University of Milan, in Italy, and colleagues found that the huntingtin protein controls the production of another protein called brain-derived neurotrophic factor (BDNF), which is essential for maintaining the type of brain cells that die off in patients with Huntington's. It is this patients' mutated huntingtin protein that cannot produce proper amounts of BDNF, which leads to brain deterioration.

"Prior to this we thought that [Huntington's] was due to a toxic activity caused by the mutant protein. Here we show that there is a loss of normal function" Dr. Elena Cattaneo said. "There must be a cure for this disease," she added, "and there must be one very soon."
'"/>




Page: 1

Related medicine news :

1. Unravelling the secrets of ‘Huntingtin’ Protein - towards the treatment of ‘Huntingtons’ Disase
2. Unravelling the secrets of ‘Huntingtin’ Protein - towards the treatment of ‘Huntingtons’ Disase
3. Ecstasy shrinks brain!!-researchers unveil the secrets of MDMA.
4. Skin cancers secrets unveiled
5. Scientists reveal the secrets of sarcasm
6. Scientist discover secrets of ageing
7. Spanish flu virus – secrets uncovere
8. US calls interrogation techniques national security secrets
9. The secrets for a healthy progeny: Mother’s diet during pregnancy
10. Unravelling the secrets of ‘Huntingtin’ Protein - towards the treatment of ‘Huntingtons’ Disase
11. Lean Protein Could Be Key to Obesity Drugs
Post Your Comments:
(Date:9/21/2014)... An experienced review website in the global market, ... and announced that FatCow ( http://www.top10bestseohosting.com/go/FatCow.com/ ), GoDaddy and ... There has been a boom in websites in recent ... increase in the number of web hosting companies that ... prices. VPS (Virtual Private Server) is the method of ...
(Date:9/21/2014)... (PRWEB) September 21, 2014 Developers and ... have announced a new transition plugin entitled Transpack ... 3 delivers high quality transitions that will add a ... Christina Austin, CEO of Pixel Film Studios. “Blurring the ... a definite game changer.” , Transpack Vol. 3 returns ...
(Date:9/21/2014)... 2014 According to latest National Vital ... rate since 1966 (10.5 births per 1,000 women in 2013). ... has risen steadily by 2 percent per year. The birth ... aged 50 and over) also rose, the first such increase ... than nine times as many first births to women aged ...
(Date:9/20/2014)... UWDress.com, a professional company of women’s dresses and related ... evening cocktail dresses . As a matter of ... very popular among worldwide customers. Now, all its evening ... 65 percent off). , All UWDress.com’s employees are ... for the global clients. The company is famous for ...
(Date:9/20/2014)... 6 Minutes to Skinny , a ... Ballantyne that is showing men and women of all ages ... body fat using simple 6-minute exercises and easy-to-follow lifestyle tips ... investigative review. , “When it comes to losing body ... out for all people,” reports Michaels. “Metabolism plays a big ...
Breaking Medicine News(10 mins):Health News:Top10BestSEOHosting.com: FatCow, GoDaddy And Bluehost Are The Best VPS Hosting Suppliers 2Health News:Pixel Film Studios Released Transpack Vol. 3 Plugin Exclusively for Final Cut Pro X 2Health News:Statistics Reveal That the Number of 'Older' First-Time Mothers Is Growing 2Health News:Statistics Reveal That the Number of 'Older' First-Time Mothers Is Growing 3Health News:Statistics Reveal That the Number of 'Older' First-Time Mothers Is Growing 4Health News:Cheap Evening Cocktail Dresses Recently Introduced At UWDress.com 2Health News:6 Minutes to Skinny: Review Exposes Craig Ballantyne’s Method to Jump Starting the Metabolism and Blasting Away Body Fat in Just 6 Minutes Per Day 2
... showing signs of changes that could lead to full-blown ... today's "baked potato generation"// could be falling prey to ... ,It has been recognised for some time that being ... of diabetes, but authentication is growing that younger patients ...
... take as much care of your hair as you do of ... that the outer layer of the hair - the cuticle - ... dry and faded.// Hair damage occurs from a range of causes ... exposure. Ideally, you'd pay as much attention to your hair as ...
... specific toxin can cause a severe, highly lethal type ... They have so far linked infection with these toxin-carrying ... tissue destruction in the respiratory tract. ,According ... of the National Reference Center for Staphylococcal Toxemia in ...
... treat both major strains of influenza in young children said ... flu season because production problems delayed its distribution. The medication, ... season. Hoffmann-La Roche informed the FDA of its production problems, ... required to do so. // ,Tamiflu is one of ...
... be suffering from anxiety or depression. According to a ... before aggressive treatments are begun// for gastrointestinal disorders. This ... harmful medications for nausea, unnecessary medical investigation and probably ... ,Haug and colleagues in the department of psychiatry conducted ...
... folic acid intake and decreasing alcohol help beat the risk ... to previous studies have shown that colon cancer often runs ... the disease, you can opt for regular colon exams, cut ... vegetables to reduce your cancer risk. ,According to ...
Cached Medicine News:Health News:Toxin connected to 'Flesh-eating' Pneumonia in Kids 2
(Date:9/19/2014)... Sept. 19, 2014 The Parenteral Drug Association ... global post-approval changes protocols. The new ... topic expressed by industry participants and regulatory authority representatives ... month in Washington, DC . Representatives ... hand for the workshop. Attendees indicated openness to engaging ...
(Date:9/19/2014)... 2014 Today, iHealth Lab Inc. announced it has ... for its first institutional round of funding. The strategic ... reach, accelerate growth and innovation, and invest in additional ... Xiaomi Ventures will join iHealth,s board of directors, bringing ... ecommerce. "We are very pleased to have ...
(Date:9/19/2014)... , September 19, 2014 ... ) has announced the addition of the ... report to their offering.      ... have been broadly classified into wide categories ... used for the treatment of different gynecological ...
Breaking Medicine Technology:PDA Launches Effort to Harmonize Global Post-Approval Changes Protocols 2iHealth Raises $25 Million to Fuel Growth and Global Market Share 2Global Gynecological Devices Market 2014-2018: Key Vendors are Bayer, Boston Scientific, CooperSurgical, Ethicon, Hologic, Medtronic, Olympus and Stryker 2Global Gynecological Devices Market 2014-2018: Key Vendors are Bayer, Boston Scientific, CooperSurgical, Ethicon, Hologic, Medtronic, Olympus and Stryker 3
... in ... developing countries, SEATTLE, Jan. 22 ... has joined the Global Health,Program as director of Global Health Delivery. ... medical and public health,efforts, including preparations for a potential influenza pandemic., ...
... Diagnostic Application of Research Technologies, FULLERTON, Calif., ... ) announced today that it has signed four ... to direct assay,research and acquire licenses for intellectual ... for the company,s future molecular,diagnostic instrument. Under the ...
Cached Medicine Technology:Dr. Rajeev Venkayya Joins Gates Foundation as Director of Global Health Delivery 2Beckman Coulter Announces Licensing Agreements for Molecular Tests with National University of Ireland, Galway 2Beckman Coulter Announces Licensing Agreements for Molecular Tests with National University of Ireland, Galway 3
Alexander periosteal elevators....
Lambotte periosteal elevators....
Cottle periosteal & skin elevator, 7 1/2", slightly curved blade, 9 mm wide....
Dolwick-Reich Condyle periosteal elevator, 17.5 cm, 7"....
Medicine Products: