Navigation Links
Unravelling the secrets of ‘Huntingtin’ Protein - towards the treatment of Huntingtins’ Disese

Huntingtons disease is an inherited disease of the nervous system due to the progressive gradual deterioration of the same, initially causing symptoms such as involuntary movements and balance problems and later on leading to declination of functions of speech as well.

All these days, until now, it was thought that this disease is due to a mutated form of the protein 'huntingtin' which is responsible for destroying the brain tissue.

Researchers have believed the mutation somehow caused the protein to be toxic. But until now, they have not been able to identify the function of the "normal" huntingtin protein present in people without the disease.

Researchers have uncovered the function of a protein that plays an important role in Huntington's disease (HD). Dr. Elena Cattaneo, from the University of Milan, in Italy, and colleagues found that the huntingtin protein controls the production of another protein called brain-derived neurotrophic factor (BDNF), which is essential for maintaining the type of brain cells that die off in patients with Huntington's. It is this patients' mutated huntingtin protein that cannot produce proper amounts of BDNF, which leads to brain deterioration.

"Prior to this we thought that [Huntington's] was due to a toxic activity caused by the mutant protein. Here we show that there is a loss of normal function" Dr. Elena Cattaneo said. "There must be a cure for this disease," she added, "and there must be one very soon."
'"/>




Page: 1

Related medicine news :

1. Unravelling the secrets of ‘Huntingtin’ Protein - towards the treatment of ‘Huntingtons’ Disase
2. Unravelling the secrets of ‘Huntingtin’ Protein - towards the treatment of ‘Huntingtons’ Disase
3. Ecstasy shrinks brain!!-researchers unveil the secrets of MDMA.
4. Skin cancers secrets unveiled
5. Scientists reveal the secrets of sarcasm
6. Scientist discover secrets of ageing
7. Spanish flu virus – secrets uncovere
8. US calls interrogation techniques national security secrets
9. The secrets for a healthy progeny: Mother’s diet during pregnancy
10. Unravelling the secrets of ‘Huntingtin’ Protein - towards the treatment of ‘Huntingtons’ Disase
11. Lean Protein Could Be Key to Obesity Drugs
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/25/2016)... ... June 25, 2016 , ... Conventional wisdom preaches the benefits of ... of the latter, setting the bar too high can result in disappointment, perhaps even ... progress toward their goal. , Research from PsychTests.com reveals that behind ...
(Date:6/24/2016)... ... June 24, 2016 , ... Marcy was in a crisis. Her son James, eight, was out ... family verbally and physically. , “When something upset him, he couldn’t control his emotions,” remembers ... would throw rocks at my other children and say he was going to kill them. ...
(Date:6/24/2016)... ... , ... Comfort Keepers® of San Diego, CA is excited to announce they ... to drive cancer patients to and from their cancer treatments. Comfort Keepers provides ... life and ongoing independence. Getting to and from medical treatments is one of ...
(Date:6/24/2016)... , ... June 24, 2016 , ... ... is proud to recognize Dr. Barry M. Weintraub as a prominent plastic surgeon ... beautiful women in the world, and the most handsome men, look naturally attractive. ...
(Date:6/24/2016)... ... 24, 2016 , ... Venture Construction Group (VCG) sponsors Luke’s Wings ... 20th at the Woodmont Country Club at 1201 Rockville Pike, Rockville, Maryland, 20852. ... service members that have been wounded in battle and their families. Venture Construction Group ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... According to a new market ... Needles, Safety Pen Needles), Needle Length (4mm, 5mm, 6mm, ... of Purchase (Retail, Non-Retail) - Trends & Global Forecasts ... market for the forecast period of 2016 to 2021. ... by 2021 from USD 1.65 Billion in 2016, growing ...
(Date:6/23/2016)... HOUSTON , June 23, 2016  MedSource ... platform as its e-clinical software solution of choice.  ... the best possible value to their clients by ... nowEDC.  The preferred relationship establishes nowEDC as the ... pricing for MedSource,s full-service clients.  "nowEDC has long ...
(Date:6/23/2016)... startling report released today, National Safety Council research shows ... plan to eliminate prescription opioid overdoses. Prescription Nation ... the worst drug crisis in recorded U.S. history, assigned a "Making ... , New Mexico , Tennessee ... states, three – Michigan , Missouri ...
Breaking Medicine Technology: