Navigation Links
Unravelling the secrets of ‘Huntingtin’ Protein - towards the treatment of ‘Huntingtons’ Disase

Huntingtons disease is an inherited disease of the nervous system due to the progressive gradual deterioration of the same, initially causing symptoms such as involuntary movements and balance problems and later on leading to declination of functions of speech as well.

All these days, until now, it was thought that this disease is due to a mutated form of the protein 'huntingtin' which is responsible for destroying the brain tissue.

Researchers have believed the mutation somehow caused the protein to be toxic. But until now, they have not been able to identify the function of the "normal" huntingtin protein present in people without the disease.

Researchers have uncovered the function of a protein that plays an important role in Huntington's disease (HD). Dr. Elena Cattaneo, from the University of Milan, in Italy and colleagues found that the huntingtin protein controls the production of another protein called brain-derived neurotrophic factor (BDNF), which is essential for maintaining the type of brain cells that die off in patients with Huntington's. It is this patients' mutated huntingtin protein that cannot produce proper amounts of BDNF, which leads to brain deterioration.

"Prior to this we thought that [Huntington's] was due to a toxic activity caused by the mutant protein. Here we show that there is a loss of normal function" Dr. Elena Cattaneo said. "There must be a cure for this disease," she added, "and there must be one very soon."
'"/>




Page: 1

Related medicine news :

1. Unravelling the secrets of ‘Huntingtin’ Protein - towards the treatment of Huntingtins’ Disese
2. Unravelling the secrets of ‘Huntingtin’ Protein - towards the treatment of Huntingtins’ Disese
3. Ecstasy shrinks brain!!-researchers unveil the secrets of MDMA.
4. Skin cancers secrets unveiled
5. Scientists reveal the secrets of sarcasm
6. Scientist discover secrets of ageing
7. Spanish flu virus – secrets uncovere
8. US calls interrogation techniques national security secrets
9. The secrets for a healthy progeny: Mother’s diet during pregnancy
10. Unravelling the secrets of ‘Huntingtin’ Protein - towards the treatment of Huntingtins’ Disese
11. Lean Protein Could Be Key to Obesity Drugs
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:1/14/2019)... ... ... Yes, the Millennials love their Bluetooth earbuds and Alexa smart speakers. But according ... is also finding a home in senior living communities. , The 2018 Active-Aging ... organizations that work with older adults about their adoption of technology over a time ...
(Date:1/14/2019)... ... , ... Trees can be overweight too! Giroud Tree and Lawn ... is a great time to clean things up on the property! , Health and ... during windy or icy storms. The crown of the tree should be pruned to ...
(Date:1/13/2019)... ... January 12, 2019 , ... ... (YPC) in conjunction with Temple University hosted a continuing education (CEU) event entitled, ... The event aimed to create a series of talks to help develop ...
(Date:1/11/2019)... ... 2019 , ... Ms. Barrios, a first generation immigrant from ... Andrews and others engaged in a systematic pattern of discrimination against Latina and ... race and by the color of their skin, and directed Ms. Barrios, a ...
(Date:1/10/2019)... ... January 10, 2019 , ... Net-Translators, an ... with MD101, a regulatory consulting company that serves the medical industry. The companies ... companies in the medical device and healthcare industries. Based in France, they join ...
Breaking Medicine News(10 mins):
(Date:1/15/2019)... ... January 15, 2019 , ... ... screening, compliance and credentialing solutions, announces it was recently acquired by Cisive, ... Cisive caters to the complex challenges and program needs of large enterprises ...
(Date:1/15/2019)... ... January 15, 2019 , ... ... penicillin allergy in their medical record, studies have shown that over 95% can ... reducing the risk of infection with dangerous resistant pathogens such as Clostridium difficile ...
(Date:1/14/2019)... , ... January 15, 2019 , ... Sigma Theta Tau ... (AJN) Book of the Year Awards. These awards are regarded as one of the ... 49th year, the AJN Book of the Year competition has recognized Sigma for the ...
Breaking Medicine Technology: