Navigation Links
Unexplained Weight Loss may Be Early Predictor of Alzheimer's

A recent research has found that inexplicable weight loss that precedes dementia by over 10 years is linked to the severity of Alzheimer changes in the brain .

Using data from the Nun Study, a prospective study of the causes of dementia in Catholic sisters, initially 75 to 102 years of age, University of South Florida researcher James Mortimer, PhD, reported that the most probable cause of the unexplained weight loss is the severity of the Alzheimer changes in the brain rather than an eating disorder or other condition associated with declining cognition. Dr. Mortimer presented the findings at the Alzheimer's Association International Conference on the Prevention of Dementia in Washington, DC.

Although an earlier study showed that individuals with lower weight for their height at the time of death had more Alzheimer brain changes at autopsy, this is the first study to demonstrate that lower weight up to 10 years earlier is particularly related to the severity of the disease.

"While weight one year or less prior to death was related to the amount of cognitive decline, this association could be explained by the severity of the Alzheimer process in the brain seen at autopsy," said Dr. Mortimer, professor of epidemiology at the USF College of Public Health.

"Given its very long duration prior to the onset of dementia, it is likely that weight loss is specifically associated with the Alzheimer disease process and not to a restriction in food intake due to cognitive decline," he said. "There is considerable evidence that Alzheimer changes in the brain precede the first symptoms of this illness by decades."

Unexplained weight loss late in life, together with other biomarkers, may help to spot those at risk of Alzheimer's disease more than a decade in the future. Identification of individuals who are at high risk of Alzheimer's long before cognitive decline becomes obvious will be decisive to its preve ntion once agents become available to slow the disease, Dr. Mortimer said.


Related medicine news :

1. Unexplained Repeat Cesarean Deliveries On The Rise In US
2. Revolutionary New Treatment Plan Developed For Treatment Of Unexplained Symptoms
3. Over 500 Sudden Unexplained Deaths Every Year, Mostly in Young Men
4. New Relief for Unexplained Chest Pain
5. New Reforms Could Cut the Number of Unexplained Infant Deaths
6. Lose Weight With New Wonder Slimming FDA approved Prescription Drug
7. Weight-Loss Drinks Can Make You Gassy
8. Smoking Linked To Low Infant Birth Weight
9. Weight gain following smoking cessation not linked to Leptin
10. Helping Kids Attain a Healthy Weight
11. Weight-loss Products Dangerous
Post Your Comments:

(Date:10/13/2017)... (PRWEB) , ... October 13, ... ... School of Pharmacy (SOP) alumni Hannah Randall, PharmD ‘17, and Jennifer Huggins, ... professionals on guideline updates for the primary prevention of cardiovascular diseases during ...
(Date:10/13/2017)... ... 2017 , ... Many families have long-term insurance that covers care for a ... waiver for care if the client has a cognitive impairment diagnosis. , “What ... is often waived, so the benefits from their insurance start immediately,” said Mechell Vieira, ...
(Date:10/13/2017)... ... October 13, 2017 , ... Global Healthcare Management’s 4th Annual Kids Fun ... NJ. This free event, sponsored by Global Healthcare Management’s CEO, Jon Letko, is ... is geared towards children of all ages; it is a non-competitive, non-timed event, which ...
(Date:10/13/2017)... ... October 13, 2017 , ... Coveros, a leader in agile ... a contract by the Center for Medicare and Medicaid Services (CMS). The Enterprise ... use of Agile methodologies in a consistent and high value manner across CMS ...
(Date:10/12/2017)... , ... October 12, 2017 , ... ... services for healthcare compliance program management, will showcase a range of technology and ... for Assisted Living (NCAL) Convention and Expo to be held October 14–18, 2017 ...
Breaking Medicine News(10 mins):
(Date:10/11/2017)... 11, 2017  True Health, a leader in ... effort during National Breast Cancer Awareness month to ... Research recently ... that more than 10 million American women are ... BRCA1 or BRCA2 and have not had testing. These ...
(Date:10/7/2017)... 2017   Provista, a proven leader in ... in purchasing power, today announced a new resource area ... Newsroom is the online home for case studies, ... bios, news releases, slideshows and events. ... of resources at their fingertips, viewers can also watch ...
(Date:10/4/2017)... OBP Medical , a leading ... today announced regulatory approval from Brazil,s ... Nacional de Vigilância Sanitária (ANVISA)) to market ... with integrated LED light source and smoke evacuation ... of a tissue pocket or cavity during surgical ...
Breaking Medicine Technology: