Navigation Links
Unexplained Weight Loss may Be Early Predictor of Alzheimer's

A recent research has found that inexplicable weight loss that precedes dementia by over 10 years is linked to the severity of Alzheimer changes in the brain .

Using data from the Nun Study, a prospective study of the causes of dementia in Catholic sisters, initially 75 to 102 years of age, University of South Florida researcher James Mortimer, PhD, reported that the most probable cause of the unexplained weight loss is the severity of the Alzheimer changes in the brain rather than an eating disorder or other condition associated with declining cognition. Dr. Mortimer presented the findings at the Alzheimer's Association International Conference on the Prevention of Dementia in Washington, DC.

Although an earlier study showed that individuals with lower weight for their height at the time of death had more Alzheimer brain changes at autopsy, this is the first study to demonstrate that lower weight up to 10 years earlier is particularly related to the severity of the disease.

"While weight one year or less prior to death was related to the amount of cognitive decline, this association could be explained by the severity of the Alzheimer process in the brain seen at autopsy," said Dr. Mortimer, professor of epidemiology at the USF College of Public Health.

"Given its very long duration prior to the onset of dementia, it is likely that weight loss is specifically associated with the Alzheimer disease process and not to a restriction in food intake due to cognitive decline," he said. "There is considerable evidence that Alzheimer changes in the brain precede the first symptoms of this illness by decades."

Unexplained weight loss late in life, together with other biomarkers, may help to spot those at risk of Alzheimer's disease more than a decade in the future. Identification of individuals who are at high risk of Alzheimer's long before cognitive decline becomes obvious will be decisive to its preve ntion once agents become available to slow the disease, Dr. Mortimer said.


'"/>




Related medicine news :

1. Unexplained Repeat Cesarean Deliveries On The Rise In US
2. Revolutionary New Treatment Plan Developed For Treatment Of Unexplained Symptoms
3. Over 500 Sudden Unexplained Deaths Every Year, Mostly in Young Men
4. New Relief for Unexplained Chest Pain
5. New Reforms Could Cut the Number of Unexplained Infant Deaths
6. Lose Weight With New Wonder Slimming FDA approved Prescription Drug
7. Weight-Loss Drinks Can Make You Gassy
8. Smoking Linked To Low Infant Birth Weight
9. Weight gain following smoking cessation not linked to Leptin
10. Helping Kids Attain a Healthy Weight
11. Weight-loss Products Dangerous
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:12/8/2016)... , ... December 08, 2016 , ... STAT courier is ... be a convenient service for Texas, they are expanding their presence in Dallas. One ... hiring spree that will bring new jobs to the Dallas and Forth Worth market. ...
(Date:12/8/2016)... ... 08, 2016 , ... Vida Health, the digital health platform that ... Canvas Ventures . Other investors include Nokia Growth Partners (NGP) and returning investor ... more consumers who are managing chronic conditions or simply want to improve ...
(Date:12/8/2016)... ... December 08, 2016 , ... Peter Zipp Insurance, an ... around the greater Phoenix metropolitan region, is announcing a charity event to provide ... the Homeless Youth Connection is to promote community awareness of the ongoing needs ...
(Date:12/8/2016)... ... 08, 2016 , ... Bill Mull Agencies, a Wichita-based firm ... around central Kansas, is joining the Youth Horizons organization for a charity event ... in Wichita, Youth Horizons works to empower area children from unstable, troubled, or ...
(Date:12/7/2016)... ... December 07, 2016 , ... Kenall Manufacturing, a leader ... MedMaster™ MPCNGX . The MPCNGX is a multi-function, sealed, LED luminaire that meets the ... light where and when it’s needed. , A 2’ x 4’ model ...
Breaking Medicine News(10 mins):
(Date:12/8/2016)... NEW YORK , Dec. 8, 2016 ... ... such as reducing loss of blood during surgeries, lowering the ... surgeries, and decreasing risks of SSIs. The patient warming systems ... and intravascular warming systems.These benefits in turn reduce the stay ...
(Date:12/8/2016)... Dec. 8, 2016 KEY FINDINGS ... grow in 2017-2023. Various reasons for growth of the ... higher incidences of chronic diseases, high recovery cost of ... services. Medical lifting sling refers to an assistive ... mobility. These slings connect to the lift and hold ...
(Date:12/8/2016)... LONDON , Dec. 8, 2016 ... diagnostics includes products and tests that are used ... grass, weed, peanuts, milk, or drugs etc. in ... developed by the immune system. The report on ... future prospects of the market. The report consists ...
Breaking Medicine Technology: