Navigation Links
Understanding how humans detect sweet taste

The research conducted by the scientist at the Monell Chemical Senses Center described in detail the mechanism behind the detection of sweet// taste by humans. Veronica Galindo-Cuspinera, PhD noted that when saccharin used in high concentration it losses its ability to taste sweet. Then the researcher found that taste perception switches back to sweetness when these high concentrations are rinsed from the mouth with water, resulting in the aftertaste experience known as sweet water taste.

This has guided the researchers to an increased understanding of how humans detect sweet taste. The study was publication in the journal Nature. Scientists from the Monell Chemical Senses Center found that when sodium saccharin and acesulfame-K were used in high concentration it inhibited the sweet taste. Paul A.S. Breslin, PhD, a Monell geneticist said that the study helps in establishing a strong foundation to understand the sweet taste receptor and come up with new sweeteners and inhibitors that can be used both by food industry and in medicine. When both the scientist worked together they found that a high concentration of saccharin prevents the sweetness of any other sweetener to be perceived at the same time.

A sweetener that gives rise to sweet water taste results as a sweet taste inhibitor. Marcel Winnig, Bernd Bufe, and Wolfgang Meyerhof of the German Institute of Human Nutrition conducted a series of molecular studies using cultured cells expressing the human sweet taste receptor to understand how it can act both as a sweetener and as a sweet inhibitor. The molecular mechanism revealed that at lower concentrations, sweeteners activate the sweet taste receptor. This is done by attaching to a high affinity binding site, leading to perception of sweetness. However at high concentrations it inhibits the cellular responses to other sweeteners by binding to a low-affinity inhibitory site which causes the receptor to shift from an activated state to an inhib itory state.

Then the water rinse removes sweet taste inhibitors from the inhibitory site, the sweet receptor is re-activated and the perception of sweetness returns. Hence in conclusion Galindo-Cuspinera said that sweet water taste can be used as a predictor for potential sweet inhibitors. This is of great use in the food industry where undesirable high sweetness occurs while replacing fats with sweet carbohydrates in case of snack foods and salad dressings. The study gives a complete knowledge of human sweet taste perception, leads directly to understand how to stimulate, manipulate, enhance, inhibit, and create synergy of sweet taste.
'"/>




Related medicine news :

1. Understanding The Predictors Of Prostate Cancer
2. Understanding Restless Legs Syndrome
3. Understanding Lung Cancer Metastasis
4. Understanding The Link Between Hormone Replacement and Respiratory Disease
5. Understanding The Risks Of Hormone Therapy
6. Understanding The Link Between Metabolic Syndrome And Drinking Patterns
7. A Better Understanding Of The Brain Network
8. Understanding The Predictor’s Of Alzheimer’s Diseae
9. Understanding The Harmful Effects Of Radiation Exposure
10. Understanding The Origin Of Tumors
11. Understanding Insulin Resistance
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:1/18/2017)... Silver Spring, MD (PRWEB) , ... January 18, 2017 , ... ... and financial consultations to families and business owners in central Maryland and the DC ... community. , Heart disease kills 787,000 people nationally every year, making it the #1 ...
(Date:1/18/2017)... N.J. (PRWEB) , ... January 18, 2017 , ... ... delivery technologies and development solutions for drugs, biologics and consumer health products, today ... will be presenting at the upcoming WCBP Conference, to be held at the ...
(Date:1/18/2017)... Hills, CA (PRWEB) , ... January 18, 2017 ... ... of dental problems ranging from gum disease to enamel erosion, and those dental ... the Massachusetts Department of Public Health, many pregnant women are failing to get ...
(Date:1/17/2017)... ... January 17, 2017 , ... Gym Source, America’s leading retailer of ... at South Dixie Hwy in Miami, FL. , “We are elated to be opening ... innovative in-store concept is designed to give clients a seamless and motivating shopping experience.” ...
(Date:1/17/2017)... Phoenix, AZ (PRWEB) , ... January 17, 2017 ... ... new and improved supplement, Healthful-Flex. , The company, owned and operated by ... the public at a reasonable price with the highest level of customer service. ...
Breaking Medicine News(10 mins):
(Date:1/18/2017)... After the recent election cycle, it is clear ... for medical and recreational purposes are shifting. The evidence shows ... of cannabis, but the focus is coming from both the ... North American legal cannabis market posted $6.7 billion in revenue ... projects sales will grow at a compound annual growth rate ...
(Date:1/17/2017)... , Jan. 17, 2017 Precision medicine ... for the treatment of disease. The approach allows ... to a therapy. The approach studies the individual ... lifestyle and environment. In January 2015, Precision Medicine ... to all diseases with more than one million ...
(Date:1/17/2017)... , Jan. 17, 2017 EU5 Glucose Monitoring ... new report, "EU5 Glucose Monitoring Market Outlook to 2022", ... market. The report provides value, in millions of US ... market segments - Blood Glucose Meters, Blood Glucose Test ... shares and distribution shares data for each of these ...
Breaking Medicine Technology: