Navigation Links
Understanding Gene Profiles Could Help Cure A Resistant Form Of Leukemia In Kids

Researchers have uncovered new genes that may help explain why 20 percent of children diagnosed with acute lymphoblastic leukemia // ( ALL ) are resistant to treatment with chemotherapy drugs.

According to researchers chemotherapy cures about 80 percent of ALL cases, but the remaining 20 percent have cancer cells that are resistant to chemotherapy drugs. In order to determine genetic predictors of ALL and the outcome researchers isolated leukemia cells from 173 newly diagnosed ALL patients and tested the cells’ sensitivity to four common chemotherapy drugs. They identified 124 genes that predict resistance to the drugs based on their expression patterns and it was found that the expression of the genes correlated with the likelihood of relapse years after treatment.

It was seen that children who had resistant patterns of gene expression had a three- to 12-fold higher risk of relapse than those whose cells had a sensitive pattern. Researchers also say that the identified genes were involved in a wide range of functions including cell communication, proliferation and development as well as the metabolism of proteins, nucleic acids and carbohydrates.

Studies in the past have identified only three of the 124 genes to be linked with ALL resistance. Thus researchers say the genes uncovered in their recent study point to new targets for future chemotherapy. However, they say that future research needs to define whether the new target genes can be used to treat ALL patients. They also add that doctors might have to fine-tune chemotherapy for each patient.
'"/>




Page: 1

Related medicine news :

1. Understanding The Predictors Of Prostate Cancer
2. Understanding Restless Legs Syndrome
3. Understanding Lung Cancer Metastasis
4. Understanding The Link Between Hormone Replacement and Respiratory Disease
5. Understanding The Risks Of Hormone Therapy
6. Understanding The Link Between Metabolic Syndrome And Drinking Patterns
7. A Better Understanding Of The Brain Network
8. Understanding The Predictor’s Of Alzheimer’s Diseae
9. Understanding The Harmful Effects Of Radiation Exposure
10. Understanding The Origin Of Tumors
11. Understanding Insulin Resistance
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/27/2016)... ... June 27, 2016 , ... ePAY ... partnership with Connance, a healthcare industry leader providing predictive analytics to optimize ... combine to provide health systems, hospitals and ambulatory surgical centers with dramatic ...
(Date:6/27/2016)... (PRWEB) , ... June 27, 2016 , ... TopConsumerReviews.com recently ... of Eyeglasses . , Millions of individuals in the United States and Canada ... become a way to both correct vision and make a fashion statement. Even celebrities ...
(Date:6/26/2016)... ... June 26, 2016 , ... On June 10-11, 2016, A ... 2016 Cereal Festival and World’s Longest Breakfast Table in Battle Creek, MI, where the ... history as home to some of the world’s leading providers of cereal and other ...
(Date:6/26/2016)... (PRWEB) , ... June 26, 2016 , ... PawPaws ... a new product that was developed to enhance the health of felines. The formula ... , The two main herbs in the PawPaws Cat Kidney Support Supplement ...
(Date:6/26/2016)... ... June 26, 2016 , ... Many ... been diagnosed with endometriosis. These women need a treatment plan to not only ... approach that can help for preservation of fertility and ultimately achieving a pregnancy. ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... , June 23, 2016 ... CAPR ), a biotechnology company focused on the ... announced that patient enrollment in its ongoing randomized ... has exceeded 50% of its 24-patient target. Capricor ... the third quarter of 2016, and to report ...
(Date:6/23/2016)... June 23, 2016 , , ... July 7, 2016 , , , , LOCATION: , , ... , , , EXPERT PANELISTS:  , , , Frost & ... Analyst, Christi Bird; Senior Industry Analyst, Divyaa Ravishankar and Unmesh Lal, ... The global pharmaceutical industry is witnessing an exceptional era. Several new ...
(Date:6/23/2016)... 2016 Revolutionary technology includes multi-speaker ... , industry leaders in advanced audiology and hearing aid ... Opn ™, the world,s first internet connected hearing aid ... devices.      (Photo: http://photos.prnewswire.com/prnh/20160622/382240 ) ... of ,world firsts,: , TwinLink™ - the ...
Breaking Medicine Technology: