Navigation Links
UC Researchers Find Potential Drug Target For SARS

Researchers at the University of Illinois at Chicago in collaboration with their colleagues from two other institutions have found the structure of an enzyme in the virus that causes SARS//, severe acute respiratory syndrome. The researchers, who have detailed these findings in the March 27 issue of the Proceedings of the National Academy of Sciences, hope that this could form a new drug target for drug makers.

"By unlocking the three-dimensional structure of this enzyme -- known as papain-like-protease (PLpro) -- we now have a molecular road map to design new drugs that could potentially treat SARS-infected patients, or perhaps patients suffering from other SARS-related illnesses such as the common cold, bronchitis or pneumonia," commented Andrew Mesecar, associate professor of pharmaceutical biotechnology in the UIC College of Pharmacy. "We are attempting to use the same approach that has been accomplished in designing effective drugs against HIV protease, which has led to the development of new drugs to fight the AIDS virus." SARS caused havoc in 2003 when it was first reported from Asia. Within a short span of time, the disease had sp[read to 29 countries in North and South America, Europe and Asia before it was finally controlled. It begins as fever, headache and body aches and severe cases develop diarrhea and pneumonia. In the 2003 outbreak, 774 people succumbed to the disease, which was diagnosed in 8,098 people worldwide, according to the World Health Organization. Mesecar said that the papain-like-protease enzyme forms the crux which is vital for trhe replication of the virus. Stooping this enzyme could inhibit the disease, he said. Contact: Sam Hostettler samhos@uic.edu 312-355-2522 University of Illinois at Chicago Source: Eurekalert
'"/>




Page: 1

Related medicine news :

1. Researchers urge caution in using ear tube surgery
2. Researchers Scale to assess the Severity of Epilepsy in Kids
3. Researchers trick Alzheimers Enzyme
4. Researchers find new HIV hiding place
5. New Hair in 15 Days Could Now Be A Possibility Say Researchers
6. Researchers developed world’s smallest toothbrus
7. Researchers discover receptor cells that can cause epilepsy
8. 15 Anti-SARS Drugs Identified By China-Europe Team of Researchers
9. Researchers reversed the process of memory loss
10. Researchers Identify Key Gene That May Help Brain Treatment
11. Researchers Discover Protein That Causes Malaria
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:9/20/2017)... ... September 20, 2017 , ... “The Financial Favor of God; ... Favor of God; Second Edition” is the creation of published author, Brooks Rathell. , ... opportunity to talk to you about the financial favor of God. Not only does ...
(Date:9/20/2017)... ... ... “Monique”: is the story of Monique, whose mother’s deteriorating physical condition forces the ... has owned four beauty salons and written a book regarding the author’s success in ... , “The doctor’s office was only three blocks away, and she could walk it, ...
(Date:9/19/2017)... ... September 19, 2017 , ... Only a few physicians were selected to receive ... Ross A. Clevens, MD, FACS . The founder and medical director of Clevens ... who trained at Yale, Harvard and the University of Michigan. He has served patients ...
(Date:9/19/2017)... ... September 19, 2017 , ... PAPA Healthcare, Inc. announced ... called, “PAPA Healthcare helps fill gaps, provide essential insights, and improve productivity.” ... operations by leveraging PAPA Healthcare’s post-acute productivity and analytics solutions. , St. Vincent’s ...
(Date:9/19/2017)... ... September 19, 2017 , ... Peter Chandonait, ... President’s Malaria Initiative (PMI) Africa Indoor Residual Spraying (AIRS) Project , has ... , The Innovation to Action Award, a USAID Catalyst Award, recognizes USAID staff ...
Breaking Medicine News(10 mins):
(Date:9/6/2017)... -- Eli Lilly and Company (NYSE: LLY ... galcanezumab and lasmiditan, two investigational treatments for migraine, at ... taking place Sept. 7-10 in Vancouver ... data from an open-label study evaluating the safety and ... 240 mg) for the prevention of migraine. Galcanezumab is ...
(Date:9/5/2017)... N.J. , Sept. 5, 2017  Getinge, ... has created a vibrant charitable donation program -- ... and support congenital heart defect research by The ... providers and the general public are encouraged to ... and submit the completed artwork to the gallery ...
(Date:9/1/2017)... Michael Penna , President and CEO ... for growth in his response to the July 13, ... seeking a buyer for eMDs. Penna,s company, Complete HealthCare ... Value Added Reseller and national leader in the independent ... "As the healthcare market continues to dictate consolidation, healthcare ...
Breaking Medicine Technology: