Navigation Links
U.S. launching cancer gene-mapping pilot

If all the ways genes that go the wrong way to cause cancer were to form a a dictionary, scientists can decipher only part of the first page.//

The U.S. government has set out to begin a $100 million US pilot project to unravel the genetic makeup of cancer, with the idea of speeding the discovery of gene culprits and treatments that are today more a matter of luck.

Dr. Francis Collins, the National Institutes of Health's genetics chief who announced the Cancer Genome project, said it is an audacious project. It's far more complex than research that mapped the human genome, a molecular blueprint for our species. However, today the technology does exist to finally track down the genetic changes required to spark any of the 200 diseases we collectively call cancer. This knowledge would be crucial to develop better treatments.

The time has come. The advances of technology have thrown up opportunities to look at the global nature of what is wrong with the cancer cell in a way undreamt of a few years ago.

People were once skeptical whether we could determine the genome of just one individual. “To map all the genes involved in cancer, we're talking about basically thousands of Human Genome Projects," Collins said.

Scientists have discovered numerous genes that play a vital role in cancer. At times a single genetic mutation is enough to spark a tumor; or it just makes people more vulnerable to the disease. Other changes could determine the difference between a fast-growing killer or a less dangerous tumor, or decide whether a particular line of treatment is likely to work.

But developing cancer usually involves about a dozen critical genetic alterations -- a domino effect -- that differ by malignancy, and scientists have uncovered only a fraction of them, an NIH working group reported earlier this year.

What makes cancer so hard in terms of really conquering the disease is its complexity. There are myriad genetic changes that drive the processes that are cancer, and every one of those can be a little different from one human to another.

A handful of so-called targeted drugs -- Herceptin, Gleevec, Iressa, Tarceva -- are proving remarkably effective at battling certain cancers in patients with specific faulty genes.

Under the Cancer Genome Project, researchers who now work independently will be able to share data in hopes of speeding such discoveries -- not just of specific gene mutations, but of chromosome rearrangements, faulty on/off switches and other abnormalities.
'"/>




Related medicine news :

1. Vitamin B12 can help in detecting cancers
2. Want skin cancer? Please have a cigarette
3. New hope for cancer victims – will vaccine cure the deadly bug
4. Clintons new problem - Is the outgoing American president suffering from skin cancer?
5. Are cancer patients being taken for a ride?
6. Breast cancer treatment to be determined by gene test
7. Ductal lavage may detect early breast cancer
8. Beware of the oral patch! It could be cancer!!!
9. New drug helps boost cancer treatment
10. Antidepressants come in handy for patients on treatment for hepatitis, cancers and multiple sclerosis
11. Lose stomach for Life....Preventive removal of stomach saves the risk of cancer
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/25/2016)... ... June 25, 2016 , ... Experts from the American ... Annual Research Meeting June 26-28, 2016, at the Hynes Convention Center in Boston. ... including advance care planning, healthcare costs and patient and family engagement. , AIR ...
(Date:6/25/2016)... ... June 25, 2016 , ... "With 30 hand-drawn hand gesture ... said Christina Austin - CEO of Pixel Film Studios. , ProHand Cartoon’s package ... Final Cut Pro X . Simply select a ProHand generator and drag it ...
(Date:6/25/2016)... City, Oklahoma (PRWEB) , ... June 25, 2016 ... ... helping both athletes and non-athletes recover from injury. Recently, he has implemented orthobiologic ... the Oklahoma City area —Johnson is one of the first doctors to perform ...
(Date:6/24/2016)... ... 24, 2016 , ... A recent article published June 14 on ... article goes on to state that individuals are now more comfortable seeking to undergo ... such as calf and cheek reduction. The Los Angeles area medical group, Beverly Hills ...
(Date:6/24/2016)... ... 24, 2016 , ... Marcy was in a crisis. Her son James, eight, was out of ... verbally and physically. , “When something upset him, he couldn’t control his emotions,” remembers Marcy. ... throw rocks at my other children and say he was going to kill them. ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... and SAN CLEMENTE, Calif. , June 24, 2016 ... mobile pulmonary function testing company, is now able to perform sophisticated ... by ndd Medical Technologies , Inc. Patients ... hospital-based labs.  Thanks to ndd,s EasyOne PRO ® , ARL patients ... get any needed testing done in the comfort of her own ...
(Date:6/24/2016)... June 24, 2016   Pulmatrix, Inc ., (NASDAQ: ... innovative inhaled drugs, announced today that it was added ... reconstituted its comprehensive set of U.S. and global ... is an important milestone for Pulmatrix," said Chief Executive ... awareness of our progress in developing drugs for crucial ...
(Date:6/23/2016)... , June 23, 2016  MedSource announced today ... its e-clinical software solution of choice.  This latest ... possible value to their clients by offering a ... preferred relationship establishes nowEDC as the EDC platform ... MedSource,s full-service clients.  "nowEDC has long been a ...
Breaking Medicine Technology: