Navigation Links
U.S. launching cancer gene-mapping pilot

If all the ways genes that go the wrong way to cause cancer were to form a a dictionary, scientists can decipher only part of the first page.//

The U.S. government has set out to begin a $100 million US pilot project to unravel the genetic makeup of cancer, with the idea of speeding the discovery of gene culprits and treatments that are today more a matter of luck.

Dr. Francis Collins, the National Institutes of Health's genetics chief who announced the Cancer Genome project, said it is an audacious project. It's far more complex than research that mapped the human genome, a molecular blueprint for our species. However, today the technology does exist to finally track down the genetic changes required to spark any of the 200 diseases we collectively call cancer. This knowledge would be crucial to develop better treatments.

The time has come. The advances of technology have thrown up opportunities to look at the global nature of what is wrong with the cancer cell in a way undreamt of a few years ago.

People were once skeptical whether we could determine the genome of just one individual. “To map all the genes involved in cancer, we're talking about basically thousands of Human Genome Projects," Collins said.

Scientists have discovered numerous genes that play a vital role in cancer. At times a single genetic mutation is enough to spark a tumor; or it just makes people more vulnerable to the disease. Other changes could determine the difference between a fast-growing killer or a less dangerous tumor, or decide whether a particular line of treatment is likely to work.

But developing cancer usually involves about a dozen critical genetic alterations -- a domino effect -- that differ by malignancy, and scientists have uncovered only a fraction of them, an NIH working group reported earlier this year.

What makes cancer so hard in terms of really conquering the disease is its complexity. There are myriad genetic changes that drive the processes that are cancer, and every one of those can be a little different from one human to another.

A handful of so-called targeted drugs -- Herceptin, Gleevec, Iressa, Tarceva -- are proving remarkably effective at battling certain cancers in patients with specific faulty genes.

Under the Cancer Genome Project, researchers who now work independently will be able to share data in hopes of speeding such discoveries -- not just of specific gene mutations, but of chromosome rearrangements, faulty on/off switches and other abnormalities.
'"/>




Related medicine news :

1. Vitamin B12 can help in detecting cancers
2. Want skin cancer? Please have a cigarette
3. New hope for cancer victims – will vaccine cure the deadly bug
4. Clintons new problem - Is the outgoing American president suffering from skin cancer?
5. Are cancer patients being taken for a ride?
6. Breast cancer treatment to be determined by gene test
7. Ductal lavage may detect early breast cancer
8. Beware of the oral patch! It could be cancer!!!
9. New drug helps boost cancer treatment
10. Antidepressants come in handy for patients on treatment for hepatitis, cancers and multiple sclerosis
11. Lose stomach for Life....Preventive removal of stomach saves the risk of cancer
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:2/24/2017)... , ... February 24, 2017 , ... Only two months ... Luxury Travel Market (ILTM) show in Cannes (France), XO Private has initiated a second ... the 420-page book measures almost a metre across when open, weighs in at more ...
(Date:2/24/2017)... , ... February 24, 2017 , ... The Smart Machine ... from Oxford University predict that 47 percent of all jobs in the United States ... “smart” and “successful.” The day of the aggressive know-it-all who steamrolls over colleagues is ...
(Date:2/24/2017)... ... 2017 , ... The narrative in “ Signal 8: An Australian Paramedic’s Story ... his paramedic experiences. Schanssema describes the tragedies he saw, as well as his struggles ... , Schanssema, initially unsure of the career path he wanted to take, found fulfillment ...
(Date:2/24/2017)... ... February 24, 2017 , ... The International Association of Eating Disorders ... Beyond What You See” body image mannequin art competition. Selected from 15 submissions from ... the winner revealed at the 31st annual iaedp Symposium, March 22 – 26 in ...
(Date:2/24/2017)... ... February 24, 2017 , ... Congratulations to Head Over ... on February 12th. Ms. Esparza qualified into this prestigious status after winning ... in Las Vegas, Nevada. Frida is one of approximately 25 gymnasts in the ...
Breaking Medicine News(10 mins):
(Date:2/24/2017)... Februar 2017 ITL Limited, ( ASX: ... ist erfreut, für das zum 31. Dezember 2016 ... exzellente Ergebnisse vorlegen zu können. Eine vollständige Präsentation ... finden Sie hier . ... 2,12 Millionen USD (Dez. 2015: 1,04 Millionen USD; +104 %) ...
(Date:2/24/2017)... NEW YORK , Feb. 23, 2017 ... gives comprehensive insights on the various drugs ... The report covers all the drugs that ... Preclinical & Clinical). The pipeline focuses on ... small molecules, antibodies, stem cell therapies, recombinant ...
(Date:2/24/2017)... DUBLIN , Feb 24, 2017 Research ... Drugs Price Analysis and Strategies - 2016" report to their ... The ... provides drug pricing data and benchmarks in the global Urinary Incontinence ... What are the key drugs marketed for Urinary Incontinence ...
Breaking Medicine Technology: