Navigation Links
U.S. launching cancer gene-mapping pilot

If all the ways genes that go the wrong way to cause cancer were to form a a dictionary, scientists can decipher only part of the first page.//

The U.S. government has set out to begin a $100 million US pilot project to unravel the genetic makeup of cancer, with the idea of speeding the discovery of gene culprits and treatments that are today more a matter of luck.

Dr. Francis Collins, the National Institutes of Health's genetics chief who announced the Cancer Genome project, said it is an audacious project. It's far more complex than research that mapped the human genome, a molecular blueprint for our species. However, today the technology does exist to finally track down the genetic changes required to spark any of the 200 diseases we collectively call cancer. This knowledge would be crucial to develop better treatments.

The time has come. The advances of technology have thrown up opportunities to look at the global nature of what is wrong with the cancer cell in a way undreamt of a few years ago.

People were once skeptical whether we could determine the genome of just one individual. “To map all the genes involved in cancer, we're talking about basically thousands of Human Genome Projects," Collins said.

Scientists have discovered numerous genes that play a vital role in cancer. At times a single genetic mutation is enough to spark a tumor; or it just makes people more vulnerable to the disease. Other changes could determine the difference between a fast-growing killer or a less dangerous tumor, or decide whether a particular line of treatment is likely to work.

But developing cancer usually involves about a dozen critical genetic alterations -- a domino effect -- that differ by malignancy, and scientists have uncovered only a fraction of them, an NIH working group reported earlier this year.

What makes cancer so hard in terms of really conquering the disease is its complexity. There are myriad genetic changes that drive the processes that are cancer, and every one of those can be a little different from one human to another.

A handful of so-called targeted drugs -- Herceptin, Gleevec, Iressa, Tarceva -- are proving remarkably effective at battling certain cancers in patients with specific faulty genes.

Under the Cancer Genome Project, researchers who now work independently will be able to share data in hopes of speeding such discoveries -- not just of specific gene mutations, but of chromosome rearrangements, faulty on/off switches and other abnormalities.
'"/>




Related medicine news :

1. Vitamin B12 can help in detecting cancers
2. Want skin cancer? Please have a cigarette
3. New hope for cancer victims – will vaccine cure the deadly bug
4. Clintons new problem - Is the outgoing American president suffering from skin cancer?
5. Are cancer patients being taken for a ride?
6. Breast cancer treatment to be determined by gene test
7. Ductal lavage may detect early breast cancer
8. Beware of the oral patch! It could be cancer!!!
9. New drug helps boost cancer treatment
10. Antidepressants come in handy for patients on treatment for hepatitis, cancers and multiple sclerosis
11. Lose stomach for Life....Preventive removal of stomach saves the risk of cancer
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/24/2016)... ... June 24, 2016 , ... Marcy was in a crisis. Her son James, eight, was ... his family verbally and physically. , “When something upset him, he couldn’t control his emotions,” ... He would throw rocks at my other children and say he was going to kill ...
(Date:6/24/2016)... ... 24, 2016 , ... Dr. Amanda Cheng, an orthodontist ... has extensive experience with all areas of orthodontics, including robotic Suresmile technology, ... , Micro-osteoperforation is a revolutionary adjunct to orthodontic treatment. It can be used ...
(Date:6/24/2016)... , ... June 24, 2016 , ... People across the ... Genome magazine’s Code Talker Award, an essay contest in which patients and their families ... to be presented at the 2016 National Society of Genetic Counselors (NSGC) Annual Education ...
(Date:6/24/2016)... Nevada (PRWEB) , ... June 24, 2016 , ... ... Vegas client, The Grove Investment Group (TGIG), has initiated cultivation and processing operations ... in Las Vegas and Pahrump, Nevada. , Puradigm is the manufacturer of a ...
(Date:6/24/2016)... ... June 24, 2016 , ... Venture Construction Group (VCG) sponsors Luke’s ... June 20th at the Woodmont Country Club at 1201 Rockville Pike, Rockville, Maryland, 20852. ... helping service members that have been wounded in battle and their families. Venture Construction ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... 24, 2016   Bay Area Lyme Foundation ... Dean Center for Tick Borne Illness , Harvard ... MIT Hacking Medicine, University of California, Berkeley, and ... the five finalists of Lyme Innovation , ... than 100 scientists, clinicians, researchers, entrepreneurs, and investors ...
(Date:6/24/2016)... CLEMENTE, Calif. , June 24, 2016  American Respiratory Labs ... company, is now able to perform sophisticated lung assessments in patients, ... Technologies , Inc. Patients are no longer limited ... ndd,s EasyOne PRO ® , ARL patients like Jeanne R. of ... done in the comfort of her own home. ...
(Date:6/24/2016)... June 24, 2016  Arkis BioSciences, a leading ... and more durable cerebrospinal fluid treatments, today announced ... Series-A funding is led by Innova Memphis, followed ... other private investors.  Arkis, new financing will accelerate ... the market release of its in-licensed Endexo® technology. ...
Breaking Medicine Technology: