Navigation Links
U.S. launching cancer gene-mapping pilot

If all the ways genes that go the wrong way to cause cancer were to form a a dictionary, scientists can decipher only part of the first page.//

The U.S. government has set out to begin a $100 million US pilot project to unravel the genetic makeup of cancer, with the idea of speeding the discovery of gene culprits and treatments that are today more a matter of luck.

Dr. Francis Collins, the National Institutes of Health's genetics chief who announced the Cancer Genome project, said it is an audacious project. It's far more complex than research that mapped the human genome, a molecular blueprint for our species. However, today the technology does exist to finally track down the genetic changes required to spark any of the 200 diseases we collectively call cancer. This knowledge would be crucial to develop better treatments.

The time has come. The advances of technology have thrown up opportunities to look at the global nature of what is wrong with the cancer cell in a way undreamt of a few years ago.

People were once skeptical whether we could determine the genome of just one individual. “To map all the genes involved in cancer, we're talking about basically thousands of Human Genome Projects," Collins said.

Scientists have discovered numerous genes that play a vital role in cancer. At times a single genetic mutation is enough to spark a tumor; or it just makes people more vulnerable to the disease. Other changes could determine the difference between a fast-growing killer or a less dangerous tumor, or decide whether a particular line of treatment is likely to work.

But developing cancer usually involves about a dozen critical genetic alterations -- a domino effect -- that differ by malignancy, and scientists have uncovered only a fraction of them, an NIH working group reported earlier this year.

What makes cancer so hard in terms of really conquering the disease is its complexity. There are myriad genetic changes that drive the processes that are cancer, and every one of those can be a little different from one human to another.

A handful of so-called targeted drugs -- Herceptin, Gleevec, Iressa, Tarceva -- are proving remarkably effective at battling certain cancers in patients with specific faulty genes.

Under the Cancer Genome Project, researchers who now work independently will be able to share data in hopes of speeding such discoveries -- not just of specific gene mutations, but of chromosome rearrangements, faulty on/off switches and other abnormalities.
'"/>




Related medicine news :

1. Vitamin B12 can help in detecting cancers
2. Want skin cancer? Please have a cigarette
3. New hope for cancer victims – will vaccine cure the deadly bug
4. Clintons new problem - Is the outgoing American president suffering from skin cancer?
5. Are cancer patients being taken for a ride?
6. Breast cancer treatment to be determined by gene test
7. Ductal lavage may detect early breast cancer
8. Beware of the oral patch! It could be cancer!!!
9. New drug helps boost cancer treatment
10. Antidepressants come in handy for patients on treatment for hepatitis, cancers and multiple sclerosis
11. Lose stomach for Life....Preventive removal of stomach saves the risk of cancer
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:4/25/2017)... ... April 25, 2017 , ... Lake Park Dental is now accepting new patients ... in Lutz, FL. With the help of this highly-effective, yet convenient system, patients can ... more discretion and less pain. , Drs. Sarah Jockin, Nicole Morganti, Sara Spear ...
(Date:4/25/2017)... ... ... Buyers and sellers in the thriving multi-billion dollar cannabis marketplace – from ... be heartened by the industry’s current surge. But another thing that unifies them is ... At last they can simply, safely and effectively end their aroma anguish thanks to ...
(Date:4/25/2017)... ... April 25, 2017 , ... Vetoquinol USA® ... introducing Flexadin UCII, part of the EQUISTRO line, at this week’s Rolex Kentucky ... horses at the immunologic level. , The scientifically-developed Flexadin UCII supports the body’s ...
(Date:4/24/2017)... ... April 24, 2017 , ... The Santana Telehealth Project was honored ... 2.0 — the American Telemedicine Association’s annual conference, on April 23 in Orlando, FL. ... telemedicine to improve the lives of the poor and underserved in other parts of ...
(Date:4/24/2017)... ... ... Bright Pink , a national non-profit organization focusing on the prevention and early detection of ... is proud to announce Katie Thiede as their new Chief Executive Officer. In January, founder ... of the Board and launched a national search to find a visionary new leader to ...
Breaking Medicine News(10 mins):
(Date:4/20/2017)...  Cogentix Medical, Inc. (NASDAQ: CGNT), a global ... Uro/Gyn and Gynecology markets with innovative and proprietary ... the Company as Senior Vice President, Marketing & ... Keswani will report directly to Darin Hammers ... is delighted that Ash has joined the Cogentix ...
(Date:4/20/2017)... 2017 Research and Markets has ... and Market Prospects: Addressing Production Complexities Through Risk Management ... ... Biosimilar Pipeline and Market Prospects: Overcoming Production Complexities Through ... assessment of the current trends in the global biosimilars ...
(Date:4/20/2017)... WOONSOCKET, R.I. , April 20, 2017 /PRNewswire/ ... (NYSE: CVS), today unveiled a new store design ... new assortment of healthier food, health-focused products and ... the store to help customers discover new offerings. ... represent the next evolution of the customer experience ...
Breaking Medicine Technology: