Navigation Links
Type 1 Diabetes Linked to Stimuli from Nervous System

It has been attested by all medical researchers that type I diabetes is caused due to breakdown in the immune system of the body.// The flawed response from the immune system was understood to be the reason behind the damage caused to islet cells in the pancreas where insulin is produced.

A recent research conducted by Canadian scientists suggests that apart from immune system, the central nervous system also plays a key role in the development of Type 1 diabetes. Statistics show that200, 000 Canadians are estimated to suffer from diabetes. This disease may result in grave complications, including loss of vision, cardiovascular complications, amputation of limbs and kidney failure. In the studied done, laboratory mice were used that were already susceptible to Type 1 diabetes. The researchers discovered that there is a perceptible link between islet cells of pancreas, and the associated nerves that sense pain and other stimuli assonated with trauma. The researchers at the Hospital for Sick Children and the University of Calgary have postulated that without this control system normal function of islet cells cannot thrive. Dr. Michael Dosch,the lead researcher is an immunologist at Sick Kids Hospital. He explained that their findings reveal a closer link between sensory nerves and immune system than they had known existed earlier.

They were really surprised to watch the effect of merely “knocking” off a few pain related sensory nerve cells. Called “substance P”, these cells are capable of amplifying pain or trigger an inflammatory process. None of the mice, in which the substance p was knocked off developed diabetes. Neither did their pancreas show any sign of inflammation.

The researchers have inferred that a malfunctioning immune system is not the only culprit responsible for triggering of Type 1 Diabetes. The nerve cells responding to pain also play a key role.

However the scientists were quite puzzled to note that injecting substance P into mice that had inflamed pancreas also reversed the process of inflammation.

The team of researchers now plans to continue their studies using human subjects with a strong family history of Type 1 diabetes in order to look for abnormalities in levels of sensitivity to pain, which could be a harbinger of tendency to develop the disease.

Diabetics often complain of peripheral neuropathy, a disorder characterized by numbness of extremities described by patients as “pins and needles” or burning. This disorder could be the result of the nervous system’s role in the development of the disease, postulated the researchers.

Since the tests are not toxic, clinical trials may soon be initiated once the effect of Substance P is studied on human beings said the researchers.

This research holds promise in timely detection of onset of diabetes, Type 1,which may help in nipping the illness in the bud.


Related medicine news :

1. Is Diabetes the Leading Cause of Kidney Failure in India
2. Diabetes and Depression often go hand-in-hand
3. Thirty minutes of work up per day reduces the risk of Diabetes
4. Diabetes on the rise
5. Irregular Periods Linked to Diabetes
6. Cinnamon combats Diabetes
7. Good News For Women With Gestational Diabetes
8. Processed Meat, Diabetes connection Found
9. Pancreatic Cancer may be linked to Diabetes
10. Gestational Diabetes linked to Chromosomal defici
11. A way to slow the progression of Type 1 Diabetes
Post Your Comments:

(Date:6/24/2016)... Fla. (PRWEB) , ... June 24, 2016 , ... Global ... Trend magazine’s 2016 Legal Elite. The attorneys chosen by their peers for this recognition ... Florida. , Seven Greenberg Traurig Shareholders received special honors as members of this year’s ...
(Date:6/24/2016)... ... , ... Comfort Keepers® of San Diego, CA is excited to announce they ... to drive cancer patients to and from their cancer treatments. Comfort Keepers provides ... life and ongoing independence. Getting to and from medical treatments is one of ...
(Date:6/24/2016)... ... June 24, 2016 , ... People across the U.S. are sharpening their pencils ... an essay contest in which patients and their families pay tribute to a genetic ... 2016 National Society of Genetic Counselors (NSGC) Annual Education Conference (AEC) this September. ...
(Date:6/24/2016)... ... 24, 2016 , ... The Haute Beauty Network, affiliated with ... as a prominent plastic surgeon and the network’s newest partner. , Dr. ... handsome men, look naturally attractive. Plastic surgery should be invisible.” He stands by ...
(Date:6/24/2016)... ... 24, 2016 , ... Strategic Capital Partners, LLC (SCP) in ... investment capital for emerging technology companies. SCP has delivered investment events and ... more than a million dollars of capital investment for five companies. ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... , June 24, 2016  Collagen Matrix, ... design, development and manufacturing of collagen and mineral ... announced today that Bill Messer has ... Marketing to further leverage the growing portfolio of ... devices. Bill joins the Collagen Matrix ...
(Date:6/24/2016)... DUBLIN , June 24, 2016 ... and Markets has announced the addition of the ... their offering. ... products and provides an updated review, including its applications ... covering the total market, which includes three main industries: ...
(Date:6/24/2016)... June 24, 2016 Dehaier Medical Systems Ltd. ... which develops, markets and sells medical devices and wearable ... signed a strategic cooperation agreement with Hongyuan Supply Chain ... Chain") on June 20, 2016, to develop Dehaier,s new ... cooperation agreement, Dehaier will leverage Hongyuan Supply Chain,s sales ...
Breaking Medicine Technology: