( evidence of anti-arthritic efficacy of...)Turmeric prevents rheumatoid arthritis: US study,Health

evidence of anti-arthritic efficacy of a complex turmeric extract that is analogous in composition to turmeric dietary supplements.

The significance, she explains, is that translating the results of trials such as these to clinical use depends on accurate information about the chemical content and biological activity of the botanical supplements available for use.

This work paves the way for the pre-clinical and clinical trials needed before turmeric supplements can be recommended for medicinal use in preventing or suppressing rheumatoid arthritis.

This study also provides the first in vivo documentation of a mechanism of action - how curcumin-containing extracts protect against arthritis. The researchers found that the curcuminoid extract inhibits a transcription factor called NF-KB from being activated in the joint.

A transcription factor is a protein that controls when genes are switched on or off. Once the transcription factor NF-KB is activated, or turned on, it binds to genes and enhances production of inflammatory proteins, destructive to the joint.

The finding that curcuminoid extract inhibits activation of NF-KB suggests that turmeric dietary supplements share the same mechanism of action as anti-arthritic pharmaceuticals under development that target NF-KB.

It also suggests that turmeric may have a use in other inflammatory disorders, such as asthma, multiple sclerosis and inflammatory bowel disease.

In addition to preventing joint inflammation, Funk's study shows that the curcuminoid extract blocked the pathway that affects bone resorption.

Source-IANS
'"/>




Page: 1 2
Related medicine news :

1. Turmeric Found To Slow Down Melanoma Growth
2. Spread of Breast Cancer can be stopped by a component in Turmeric
3. Turmeric And Cabbage effective against prostate cancer
4. Turmeric and Onions-Weapons against Colon Cancer
5. Turmeric to prevent arthritis and osteoporosis
6. Turmeric in the Fight Against Prostate Cancer
7. Breast Feeding prevents obesity later on in life
8. Regular exercise prevents hip fractures
9. Gel prevents pregnancy
10. Staying mentally energitic prevents Alzheimers
11. Consuming fish prevents dementia risk