Navigation Links
Tuberculosis: The Bacillus Takes Refuge in Adipose Cells

A team from the Institute Pasteur has recently shown that the tuberculosis bacillus hides from the immune system in its host's fat cells. //This formidable pathogen is protected against even the most powerful antibiotics in these cells, in which it may remain dormant for years.

This discovery, published in PLoS ONE, sheds new light on possible strategies for fighting tuberculosis. Attempts to eradicate the bacillus entirely from infected individuals should take these newly identified reservoir cells into account.

Mycobacterium tuberculosis, the bacillus responsible for tuberculosis can hide, in a dormant state, in adipose cells throughout the body. The bacterium is protected in this cellular environment, to which the natural immune defences have little access, and is inaccessible to isoniazid, one of the main antibiotics used to treat tuberculosis worldwide. These results were obtained by Olivier Neyrolles* and his colleagues from the Mycobacterial Genetics Unit directed by Brigitte Gicquel at the Institute Pasteur, in collaboration with Paul Fornès, a pathologist from H?pital Européen Georges Pompidou. They raise questions of considerable importance in the fight against tuberculosis.

Tuberculosis kills almost two million people worldwide every year and is considered by the World Health Organization to represent a global health emergency. However, the bacillus is much more prevalent in the world's population than the statistics would lead us to believe, because only 5 to 10% of those infected actually develop tuberculosis. The bacillus may be present in a significant proportion of the population, remaining in a "dormant" state in the body, sometimes for years, and may be "reactivated" at any time. The risk of reactivation is particularly high in immunocompromised individuals, such as those infected with AIDS: the HIV virus and the tuberculosis bacillus make a formidable team, with each infectious agent facilitating the progression
'"/>




Page: 1 2

Related medicine news :

1. World Health Organisation Takes a Historic Decision and Approves Treaty to Discourage Smoking
2. World Health Organisation Takes a Historic Decision and Approves Treaty to Discourage Smoking
3. World Health Organisation Takes a Historic Decision and Approves Treaty to Discourage Smoking
4. Bhitarkanika Sanctuary In Orissa Takes Precaution To Monitor Bird Flu
5. Government Takes Tough Stand Against Falling Sex Ratio
6. Bill Gates Takes Personal Interest in AIDS Program
7. Wake Up Call: U.N Takes Stock to Curb Fake Medicines Racket
8. 37 times unlucky – Failure to Diagnose Cancer, Takes the Life of a 31 year old fathe
9. So (y) Good: Soy Meal Takes-Off After Bird-Flu Crisis
10. Government Takes Steps to Reduce Binge Drinking Among Britons
11. Its High Time the Australian Government Takes Steps against Diabetes
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Tuberculosis The Bacillus Takes Refuge Adipose Cells

(Date:7/30/2014)... (PRWEB) July 30, 2014 We know pregnancy ... to peanut butter and ice cream—but the latest episode of ... MDs , just posted online, has a recipe that is ... a James Beard Award-winning chef serves up an easy recipe ... is the executive chef at Rasika, which was named one ...
(Date:7/30/2014)... 30, 2014 Chinese researchers say a protein ... plasma can be used as a prognostic indicator in people ... read the full article on the study , just posted ... Department of Respiratory Medicine at Shandong University Hospital in China ... patients between 1995 and 2013. They found that, the ...
(Date:7/30/2014)... It is often said the reason that most people ... life is because they only use about ten per cent of ... belief is only an erroneous myth propagated as an excuse ... only “smarter”. , So, success in life is defined not just ... hard for that success. Thankfully, some people have finally figured out ...
(Date:7/30/2014)... New York, NY (PRWEB) July 30, 2014 ... managed IT solutions firm based in New York City, ... cabling infrastructure for the midtown headquarters of a large ... corporate and investment banking. , Chico Ramnarayan, CEO of ... is an opportunity for us to further develop what ...
(Date:7/30/2014)... According to the Critical Bench Program 2.0 Pdf review recently ... men who want to discover how to increase their ... a few months. Inside this book, learners will discover a ... avoid the aches and pains. , Vkool reveals in its ... the reason why stretching and warming up is so important ...
Breaking Medicine News(10 mins):Health News:What to Eat When You’re Expecting 2Health News:Study Finds Common Blood Protein May Predict Mesothelioma Survival, Reports Surviving Mesothelioma 2Health News:Brain Evolution System - #1 Brainwave Entrainment Meditation Program Review | Unleashing One’s Ultimate Potential Improving Mind Power – Vinamy 2Health News:Brain Evolution System - #1 Brainwave Entrainment Meditation Program Review | Unleashing One’s Ultimate Potential Improving Mind Power – Vinamy 3Health News:The Critical Bench Program 2.0 Pdf Review Exposes Mike Westerdal's Guide for Increasing Bench Press – Vkool.com 2Health News:The Critical Bench Program 2.0 Pdf Review Exposes Mike Westerdal's Guide for Increasing Bench Press – Vkool.com 3
... various arteries wear away in a short period of time. ... a by pass surgery. The other alternative to stainless steel ... effective in helping blood flow through thigh arteries clogged by ... in the New England Journal of Medicine. These nitinol stents ...
... blueprint for handling a pandemic, state and local health officials ... of lethal influenza in the U.S. ,While the ... the risk of a pandemic and its transmission, ``the center ... communities,'' the report said. ,A preliminary $7.1 billion ...
... Scotland's University of Dundee, eggplants, green capsicum and zucchini become ... becomes heavily acidic when stewed. But the study says that ... the cooking method. , Publishing his findings in the ... Dentistry, Dr Graham Chadwick said that the study was prompted ...
... an explanation from medical superintendent of AIIMS for its ... after a boy, suffering from cancer//, became infected with ... ,Aggrieved with the defensive attitude of AIIMS, ... its unwillingness to disclose details of the donor whose ...
... African heads of state plan to meet this week in ... spread of infectious diseases// like HIV/Aids, malaria, tuberculosis. ... increasing health spending to at least 15 per cent of ... the pandemic of Aids as well as other diseases. ...
... The ill-effects of mosquito bites on the health of ... recent study into this, has shown the positive impact ... when they chose to sleep under the insecticide-treated nets. ... babies, if adequate protection against mosquito bites is enabled. ...
Cached Medicine News:Health News:Bush Unveils Latest Blueprint for Handling Bird Flu Pandemic 2Health News:Bush Unveils Latest Blueprint for Handling Bird Flu Pandemic 3Health News:Review of Reversal of Spread of Diseases in Africa 2Health News:Health of Mothers and Children Show Improvement after Use of Insecticide-Treated Bed Nets 2Health News:Health of Mothers and Children Show Improvement after Use of Insecticide-Treated Bed Nets 3
(Date:7/30/2014)... July 30, 2014 /PRNewswire-iReach/ -- This is a ... Chinese Heparin sodium (CAS 9041-08-1) & calcium (CAS ... information of Heparin sodium (CAS 9041-08-1) & calcium ... technology. The report then explores global and China,s ... calcium (CAS 37270-89-6) listing their product specification, capacity, ...
(Date:7/30/2014)... -- Hospira, Inc. (NYSE: HSP ), the ... technologies, today reported results for the second quarter ... quarter were $1.1 billion and adjusted* diluted earnings ... items as described later in this press release ... Accepted Accounting Principles (GAAP) basis, second-quarter 2014 diluted ...
(Date:7/30/2014)... , July 30, 2014   Medical Equipment Solutions, ... been awarded a Department of Defense (US Army) contract ... supply a mobile MRI diagnostic machine and technical support ... (WOSB) through the Small Business Administration (SBA), Medical Equipment ... field with the latest medical diagnostic equipment. The SBA ...
Breaking Medicine Technology:Heparin Sodium & Calcium Industry for Global and Chinese Markets Forecast to 2019 2Heparin Sodium & Calcium Industry for Global and Chinese Markets Forecast to 2019 3Heparin Sodium & Calcium Industry for Global and Chinese Markets Forecast to 2019 4Heparin Sodium & Calcium Industry for Global and Chinese Markets Forecast to 2019 5Hospira Reports Second-Quarter 2014 Results 2Hospira Reports Second-Quarter 2014 Results 3Hospira Reports Second-Quarter 2014 Results 4Hospira Reports Second-Quarter 2014 Results 5Hospira Reports Second-Quarter 2014 Results 6Hospira Reports Second-Quarter 2014 Results 7Hospira Reports Second-Quarter 2014 Results 8Hospira Reports Second-Quarter 2014 Results 9Hospira Reports Second-Quarter 2014 Results 10Hospira Reports Second-Quarter 2014 Results 11Hospira Reports Second-Quarter 2014 Results 12Hospira Reports Second-Quarter 2014 Results 13Hospira Reports Second-Quarter 2014 Results 14Hospira Reports Second-Quarter 2014 Results 15Hospira Reports Second-Quarter 2014 Results 16Hospira Reports Second-Quarter 2014 Results 17Hospira Reports Second-Quarter 2014 Results 18Hospira Reports Second-Quarter 2014 Results 19Hospira Reports Second-Quarter 2014 Results 20Hospira Reports Second-Quarter 2014 Results 21Hospira Reports Second-Quarter 2014 Results 22Hospira Reports Second-Quarter 2014 Results 23Hospira Reports Second-Quarter 2014 Results 24Hospira Reports Second-Quarter 2014 Results 25Hospira Reports Second-Quarter 2014 Results 26Hospira Reports Second-Quarter 2014 Results 27Hospira Reports Second-Quarter 2014 Results 28Hospira Reports Second-Quarter 2014 Results 29Hospira Reports Second-Quarter 2014 Results 30Hospira Reports Second-Quarter 2014 Results 31Medical Equipment Solutions Corp. Awarded $2 Million contract To Service DoD 2
... brand drug "copay coupon" promotions, which lure insured consumers ... by $2.1 billion in Florida over the next decade ... new research from Visante and released by the ... these promotions by state and local government workers alone ...
... PharmAthene, Inc. (NYSE Amex: PIP ) announced today ... agent bioscavenger programs will be presented at the 2011 Chemical ... held in Las Vegas, NV, November 14-18, 2011. ... biodefense industry meetings and it is an honor to present ...
Cached Medicine Technology:Brand Drug 'Copay Coupons' Undermine Generics, Raise Health Costs by $2.1 Billion in Florida 2PharmAthene to Present at the 2011 Chemical and Biological Defense Science and Technology Conference 2PharmAthene to Present at the 2011 Chemical and Biological Defense Science and Technology Conference 3
... mirrors angled at 76°, 66° and 60°. ... well as central and peripheral fundus viewing and ... angled and spaced 120° apart to eliminate "gaps" ... of the lens also provides direct observation of ...
The Mid Field 30° lens has a bi-concave design to provide a wider field of view with a 30 degree offset image....
... 30° Prism are designed for ... recommended for tractional retinal detachments ... retinal detachment. They can be ... other midperipheral laser applications. Direct ...
... The Chalam 15° Prism ... pathologies and are recommended for ... etc.) and Rhegmatogenus retinal detachment. ... panretinal photocoagulation and other midperipheral ...
Medicine Products: