Navigation Links
'Triple Negative' Breast Cancers Seem to Affect the Young, Minority

Breast cancers of the “triple negative” type are destructive and lethal, and tend to strike the young, poor minority women, according to a novel// study Published in the May 1, 2007 issue of CANCER.

The study has indicated that these tumors occur commonly among women who are African American and Hispanic, below 40 years old, and who belong to the lower socioeconomic status (SES). The study also showed that triple negative tumors are linked with delayed diagnosis and shorter survival.

Tumor and tissue markers provide important information, including disease type and prognosis. Three important markers in breast cancer are estrogen receptor (ER), human epidermal growth factor receptor 2 (HER2), and progesterone receptor (PR). In particular, these markers are useful in selecting appropriate adjuvant therapy and prognosis. Around 15 percent of breast cancers do not express any of these markers and are generally identified as basal-like subtypes. While these “triple negative” tumors are associated with poor prognosis and survival, hormone adjuvant therapy failure, and are often identified in African American women, little is understood about other associated demographic risk factors.

Katrina Bauer from the Public Health Institute in Sacramento, California and colleagues compared the demographic, clinical and survival characteristics of 6,370 women diagnosed with triple negative breast cancers with 44,704 women with other breast cancers.

The authors found that race and age, in particular, as well as socioeconomic status were risk factors for this type of breast cancer. Compared to Caucasians, African American women were at greatest risk followed by Hispanic women. Women under 40 years old were at greater risk than women over 60 years old. Women living in lower SES were also at higher risk compared to the highest SES.

Clinically, these tumors were more aggressive, diagnosed at more advanced stages. They were also a ssociated with shorter survival, regardless of stage at diagnosis. African American women had the poorest five-year survival, with only 14 percent alive five years after diagnosis.

From these results, Ms. Bauer and co-authors conclude that “age less than 40 years, being non-Hispanic black and, to a lesser extent, being Hispanic, are clearly the most powerful risk factors for this poor prognosis subtype of breast cancer.”

Source-EurekalertSAV
'"/>




Related medicine news :

1. Consensus on "Combination Therapy" for Breast Cancer
2. Breast cancer treatment to be determined by gene test
3. Breast Feeding prevents obesity later on in life
4. Breast milk is essential
5. Breast Cancer Surgery Causes Psychological problems
6. Breast cancer evidence
7. Letrozole Beats Tamoxifen in Breast Cancer Therapy
8. Breast screening among diabetic women
9. Breast feeding can alter hormones
10. Diet, Sunlight connected to Breast Cancer Risk
11. Additional Radiotheraphy for Breast Cancer
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:4/29/2016)... ... 29, 2016 , ... Conditions were ideal for Global Lyme Alliance’s (GLA) 2nd ... sunny skies, a light breeze and temperatures in the 60s. Over 400 runners, walkers ... and Walk and 1-mile walk were held to increase awareness about Lyme disease ...
(Date:4/29/2016)... ... 2016 , ... Spine Team Texas, a comprehensive spine physician group specializing in ... physicians has been invited to be a featured speaker at the Texas Society of ... April 30, 2016. , Dr. R. Scott McPherson, a physical medicine and rehabilitation ...
(Date:4/29/2016)... ... April 29, 2016 , ... ... announces the Gyrociser, an exercise invention which aids in proper muscle development. , ... Cooper, CEO and Creative Director of World Patent Marketing. "Globalization has threatened the ...
(Date:4/29/2016)... ... April 29, 2016 , ... Dr. Robert Mondavi, one of ... improve smiles. Cosmetic dentistry is a fast-growing field as more patients are discovering the ... to learn more about the options currently available to them and which ones might ...
(Date:4/29/2016)... ... , ... For those who skip meals occasionally (which is pretty much everyone), ... many new lifestyle diet tips offered by nutritionists Pam Bonney and Priya Lawrence of ... show. Bonny and Lawrence noted that because proper nutrition, including water, provides energy during ...
Breaking Medicine News(10 mins):
(Date:4/28/2016)... 28, 2016  While Abbott,s announced purchase of ... valve repair and stent business, healthcare research firm ... more firmly into patient monitoring.  Kalorama said that ... device areas, with double-digit growth expected the next ... Advanced Remote Patient Monitoring . Abbott Laboratories ...
(Date:4/28/2016)... 28, 2016 Treato , ... healthcare, announced today that it has been named a ... Vendor in Life Sciences, 2016, Stephen Davies ... report focuses on life-science- oriented analytics, algorithms and smart ... and doctors, confirm medication ingestion, and analyze unstructured information. ...
(Date:4/28/2016)... 2016  ValGenesis, Inc., the market leader ... today announced that a prominent world provider ... chronic kidney failure has selected ValGenesis Validation ... validation process. The global medical device manufacturer ... manage their validation processes electronically. Upon completion ...
Breaking Medicine Technology: