Navigation Links
'Triple Negative' Breast Cancers Seem to Affect the Young, Minority

Breast cancers of the “triple negative” type are destructive and lethal, and tend to strike the young, poor minority women, according to a novel// study Published in the May 1, 2007 issue of CANCER.

The study has indicated that these tumors occur commonly among women who are African American and Hispanic, below 40 years old, and who belong to the lower socioeconomic status (SES). The study also showed that triple negative tumors are linked with delayed diagnosis and shorter survival.

Tumor and tissue markers provide important information, including disease type and prognosis. Three important markers in breast cancer are estrogen receptor (ER), human epidermal growth factor receptor 2 (HER2), and progesterone receptor (PR). In particular, these markers are useful in selecting appropriate adjuvant therapy and prognosis. Around 15 percent of breast cancers do not express any of these markers and are generally identified as basal-like subtypes. While these “triple negative” tumors are associated with poor prognosis and survival, hormone adjuvant therapy failure, and are often identified in African American women, little is understood about other associated demographic risk factors.

Katrina Bauer from the Public Health Institute in Sacramento, California and colleagues compared the demographic, clinical and survival characteristics of 6,370 women diagnosed with triple negative breast cancers with 44,704 women with other breast cancers.

The authors found that race and age, in particular, as well as socioeconomic status were risk factors for this type of breast cancer. Compared to Caucasians, African American women were at greatest risk followed by Hispanic women. Women under 40 years old were at greater risk than women over 60 years old. Women living in lower SES were also at higher risk compared to the highest SES.

Clinically, these tumors were more aggressive, diagnosed at more advanced stages. They were also a ssociated with shorter survival, regardless of stage at diagnosis. African American women had the poorest five-year survival, with only 14 percent alive five years after diagnosis.

From these results, Ms. Bauer and co-authors conclude that “age less than 40 years, being non-Hispanic black and, to a lesser extent, being Hispanic, are clearly the most powerful risk factors for this poor prognosis subtype of breast cancer.”


Related medicine news :

1. Consensus on "Combination Therapy" for Breast Cancer
2. Breast cancer treatment to be determined by gene test
3. Breast Feeding prevents obesity later on in life
4. Breast milk is essential
5. Breast Cancer Surgery Causes Psychological problems
6. Breast cancer evidence
7. Letrozole Beats Tamoxifen in Breast Cancer Therapy
8. Breast screening among diabetic women
9. Breast feeding can alter hormones
10. Diet, Sunlight connected to Breast Cancer Risk
11. Additional Radiotheraphy for Breast Cancer
Post Your Comments:

(Date:6/26/2016)... ... June 26, 2016 , ... On June 10-11, 2016, A Forever Recovery, ... Festival and World’s Longest Breakfast Table in Battle Creek, MI, where the rehabilitation facility ... home to some of the world’s leading providers of cereal and other breakfast foods. ...
(Date:6/26/2016)... Charlotte, NC (PRWEB) , ... June 26, 2016 , ... Brent Kasmer, a legally blind ... able to be personalized through a fitness app. The fitness app plans to fix the ... solutions currently only offer a one size fits all type program , They ...
(Date:6/25/2016)... (PRWEB) , ... June 25, 2016 , ... Austin residents ... the American College of Mohs Surgery and to Dr. Russell Peckham for medical and ... highly effective treatment for skin cancer. The selective fellowship in Mohs Micrographic Surgery completed ...
(Date:6/25/2016)... ... June 25, 2016 , ... First Choice Emergency Room , the ... Ogunleye, as the Medical Director of its new Mesquite-Samuell Farm facility. , “We ... new Mesquite location,” said Dr. James M. Muzzarelli, Executive Medical Director of First Choice ...
(Date:6/25/2016)... ... June 25, 2016 , ... On Friday, June 10, ... Bronze Wellness at Work award to iHire in recognition of their exemplary accomplishments in ... the 7th annual Maryland Workplace Health & Wellness Symposium at the BWI Marriott in ...
Breaking Medicine News(10 mins):
(Date:6/26/2016)... 2016 Jazz Pharmaceuticals plc (Nasdaq: ... Hart-Scott-Rodino Antitrust Improvements Act of 1976, as amended ("HSR"), ... Inc. ("Celator"; Nasdaq: CPXX ) expired effective ... As previously announced on May 31, 2016, ... agreement under which Jazz Pharmaceuticals has commenced a tender ...
(Date:6/24/2016)... Calif. , June 24, 2016  Global ... a biopharmaceutical company developing novel therapeutics for the ... needs, today announced the closing of its previously ... common stock, at the public offering price of ... the offering were offered by GBT. GBT estimates ...
(Date:6/24/2016)... 2016 Dehaier Medical Systems Ltd. (NASDAQ: ... markets and sells medical devices and wearable sleep respiratory ... strategic cooperation agreement with Hongyuan Supply Chain Management Co., ... June 20, 2016, to develop Dehaier,s new Internet medical ... Dehaier will leverage Hongyuan Supply Chain,s sales platform to ...
Breaking Medicine Technology: