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Trauma Exposure can Affect Brain Function Several Years After Event

in the past was associated with emotional responses several years later in people who were close to the initial trauma. Yet, the participants did not meet the criteria for a diagnosis of PTSD, depression or anxiety at time of imaging. All the participants were screened for psychiatric, medical and neurological illnesses.

This finding indicates that a heightened amygdala reactivity following high-intensity trauma exposure may be slow to recover and can be responsible for heightened reactions to everyday emotional stimuli, said the authors. Furthermore, the group closest to the World Trade Center on 9/11 reported more current symptoms and more symptoms at the time of the trauma than the group further from 9/11. These symptoms included increased arousal (e.g., difficulty sleeping, irritability, hypervigilance), avoidance (e.g., not wanting to go downtown when they used to enjoy doing so), and intrusion (e.g., recurrent and distressing memories or dreams). And, those who reported 9/11 as their worst and most intense trauma experienced in their life time also had more brain activity when viewing the fearful faces.

Our findings suggest that there may be long-term neurobiological correlates of trauma exposure, even in people who appear resilient. Since these effects were observable using mild, standardized emotional stimuli (not specific trauma reminders), they may extend further into everyday life than previously thought, said Dr. Ganzel. We have known for a long time that trauma exposure can lead to subsequent vulnerability to mental health disorders years after the trauma. This research is giving us clues about the biology underlying that vulnerability. Knowing whats going on will give us a better idea how to help.


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