( Exposure to trauma may create enough ch...)Trauma Exposure can Affect Brain Function Several Years After Event,Health

Exposure to trauma may create enough changes in the brain to sensitize people to overreact to an innocuous facial gesture years later , even in people who dont have a stress-related disorder, says new research. It appears that proximity to high-intensity traumas can have long lasting effects on the brain and behavior of healthy people without causing a current clinical disorder. But these subtle changes could increase susceptibility to mental health problems later on.

Evidence that trauma can have long-term effects on the brains of healthy individuals was demonstrated by measuring adults reactions to emotional stimuli several years after witnessing a trauma, said lead author Barbara Ganzel, PhD, and colleagues. In the experiment, 22 healthy adults viewed fearful and calm faces while undergoing functional magnetic resonance imaging (fMRI) to measure their bilateral amygdala activity (part of the brain that judges emotional intensity, and that forms and stores emotional memories) between 3.5 and 4 years after September 11, 2001.

All of the participants had some level of exposure to the events of September 11. The authors wanted to determine whether close proximity to a traumatic event - September 11 - sensitized parts of the brain to emotional stimuli 41 and 48 months after the terrorist attacks. Eleven of the participants were within 1.5 miles of the World Trade Center on September 11, 2001 and the other 11 participants lived at least 200 miles away [control group]. The control group those participants living at least 200 miles from New York on 9/11/01 subsequently moved to the New York metropolitan area at the time of the MRI scanning.

According to the study, participants who were within 1.5 miles of the World Trade Center on 9/11 had significantly higher bilateral amygdala activity to fearful versus calm faces compared to those who were living more than 200 miles away. These results show that exposure to traumatic events
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