Navigation Links
Trastuzumab therapy effective for Breast cancer patients with Her-2/neu positive

Researchers Edith Perez and Edward Romond reported from two separate trials that Breast cancer patients with Her2-positive were effectively treated with Herceptin therapy using trastuzumab. //The results of their study were published in the journal The New England Journal of Medicine. The researchers compiled results from two clinical trials, which compared patients getting only chemotherapy with patients receiving both chemotherapy and trastuzumab. Use of Herceptin drug has become very important as more than one million women are diagnosed of breast cancer each year around the world and of which 25% of patients have Her-2/neu positive status. Her-2 positive patients do not respond positively and effectively to routine chemotherapy drugs, which require trastuzumab therapy.

The study recruited a total of 3,351 patients of which 2,043 patients were enrolled in National Surgical Adjuvant Breast and Bowel Project (NSABP) and 1,633 patients were enrolled in two groups of North Central Cancer Treatment Group (NCCTG) trial N9831. The study results showed that out of 1,679 control patients 261 patients developed recurrence breast cancer disease compared to 133 in the group receiving trastuzumab. At three years, 90.4 percent of women receiving trastuzumab were disease free, compared to 81.5 percent of women in the control group. There also was a measurable reduction in the development of other non-breast primary cancers in the B-31 trial for women receiving trastuzumab. Overall survival also appeared to be impacted, with only 62 deaths in the trastuzumab group as compared with 92 in the control group.

NCCTG Trial: NCCTG trial was investigated by Dr. Perez and his team, the clinical trial compared three chemotherapy drugs treatment of which two of the drug treatments contained trastuzumab therapy with one dosage concurrent with weekly paclitaxel, the other after completion of paclitaxel.

NSABP Trial: Investigators compared treatment with o
'"/>




Page: 1 2

Related medicine news :

1. Acupuncture May Help Chemotherapy Side Effects
2. Antioxidants protect health tissue in people undergoing radiation therapy.
3. Distraction therapy found very effective in postoperative patients
4. Acupuncture superseeds massage therapy for short term relief of pain
5. Ovarian cancer in relationship with Hormone therapy
6. New therapy better at increasing bone density
7. Gene therapy - Aim to improve blood flow
8. Gene therapy restores sight
9. Heat therapy relieves back pain
10. Radiotherapy helps in colon cancer
11. New therapy for pimples
Post Your Comments:
(Date:8/28/2014)... with nasal septum cells. Researchers at the University and ... from the nasal septum are able to adapt to ... repair articular cartilage defects. The nasal cartilage cells, ability ... associated with the expression of so-called HOX genes. The ... the research results together with the report of the ...
(Date:8/28/2014)... working out how to safely increase the radiotherapy dose ... local control and survival. , Standard treatment for locally ... radiotherapy and chemotherapy. Traditionally this is planned in a ... be enough to stop tumour growth. , The potential ... varies between patients and depends on the size and ...
(Date:8/28/2014)... 28, 2014 Parker Waichman LLP, a ... years fighting to ensure that the heroes of 9/11 ... coverage to WTC victims who developed 9/11-related cancer was ... Accountability Office (GAO). According to a statement issued by ... report is entitled “World Trade Center Health Program: Approach ...
(Date:8/28/2014)... By Steven Reinberg ... -- Treating pre-cancerous skin spots with a type of light ... freezing the lesions with liquid nitrogen, a new study suggests. ... on the scalp and face of people with fair complexions ... review of prior research found that people who underwent the ...
(Date:8/28/2014)... Alexandria, VA (PRWEB) August 28, 2014 ... Foundation) will interview Stephen Isaacs, the chairperson, president and ... the Foundation’s Meet the Mesothelioma Experts live ... Foundation’s executive director and mesothelioma expert nurse practitioner, ... the interview will be Aduro BioTech’s experimental therapy for ...
Breaking Medicine News(10 mins):Health News:From nose to knee: Engineered cartilage regenerates joints 2Health News:Research demonstrates potential method to better control lung cancer using radiotherapy 2Health News:GAO Report Reaffirms Decision to Add Cancers to List of Illnesses Covered under the Zadroga Act, Parker Waichman LLP Comments 2Health News:GAO Report Reaffirms Decision to Add Cancers to List of Illnesses Covered under the Zadroga Act, Parker Waichman LLP Comments 3Health News: Light Therapy a Good Option for Pre-Cancerous Skin Lesions, Study Says 2Health News: Light Therapy a Good Option for Pre-Cancerous Skin Lesions, Study Says 3Health News:New Clinical Trial: Using the Listeria Virus to Fight Mesothelioma 2Health News:New Clinical Trial: Using the Listeria Virus to Fight Mesothelioma 3
... 22 Although Attention Deficit ... as only affecting children, for nearly 9 million adults ... reality. According to the National Institutes of Mental Health, ... to a job, remembering or keeping appointments and being ...
... Earn Decision Resources, Clinical Gold Standard Status for ... Report from Decision ResourcesWALTHAM, Mass., April 22 ... and advisory firms for pharmaceutical and healthcare issues, ... on overall survival as the attribute that most ...
... -- Drug side effects are a major problem,for the ... can warrant,drug withdrawal. Unfortunately, these problems often emerge only ... millions of patients. , Identifying ... the,clinic is a major focus of ReproCELL. Current cardiotoxicity ...
... New Plan Designs Help Employers and Their Employees Manage ... Life Insurance Company of America (Guardian), one of the ... employee and voluntary benefits for small and mid-sized companies, ... lineup that will broaden access to more affordable dental ...
... April 22 Celator Pharmaceuticals today ... CPX-351 (Cytarabine:Daunorubicin) Liposome Injection in consolidation treatment for ... in combination with biological agents for the treatment ... Annual Meeting of the American Association for Cancer ...
... 22 /PRNewswire-FirstCall/ - Hard To Treat Diseases (HTDS) ... Sanja Pekovic provided updates from a recent medical ... Gesellschaft - Nederlandse Anatomen Vereniging, Antwerpen, 27-30 March ... of recent positive testing being conducted related to ...
Cached Medicine News:Health News:Video: Adults 'Facing' ADHD: ADHD Allies(TM) Offers Unique Online Community for Adults with ADHD on New Facebook(R) Page 2Health News:Video: Adults 'Facing' ADHD: ADHD Allies(TM) Offers Unique Online Community for Adults with ADHD on New Facebook(R) Page 3Health News:Video: Adults 'Facing' ADHD: ADHD Allies(TM) Offers Unique Online Community for Adults with ADHD on New Facebook(R) Page 4Health News:Video: Adults 'Facing' ADHD: ADHD Allies(TM) Offers Unique Online Community for Adults with ADHD on New Facebook(R) Page 5Health News:Surveyed Experts Indicate That the Combination of Sutent and Taxol Has Advantages Over the Combination of Avastin and Taxol in the Treatment of Metastatic Triple-Negative Breast Cancer 2Health News:Surveyed Experts Indicate That the Combination of Sutent and Taxol Has Advantages Over the Combination of Avastin and Taxol in the Treatment of Metastatic Triple-Negative Breast Cancer 3Health News:New Stem Cell Technology to Improve Drug Safety 2Health News:Guardian Adds New Cost-Conscious Options to Group Dental Lineup 2Health News:Celator(R) Pharmaceuticals Presents New Data on CPX-351 And CPX-1 at the American Association for Cancer Research 2Health News:Celator(R) Pharmaceuticals Presents New Data on CPX-351 And CPX-1 at the American Association for Cancer Research 3Health News:Hard To Treat Diseases (HTDS) Slavica BioChem Update on Research Activities 2Health News:Hard To Treat Diseases (HTDS) Slavica BioChem Update on Research Activities 3
(Date:8/28/2014)... LONDON , Aug. 28, 2014  A candidate Ebola ... Gambia and Mali ... trials of potential vaccines aimed at preventing the disease that has ... West Africa . Human trials of this ... (NIH) and GlaxoSmithKline, are to be accelerated with funding from an ...
(Date:8/28/2014)... , Aug. 28, 2014 Nonin Medical, ... leader in noninvasive medical monitoring, today announced that the ... Model 3231 OEM/eHealth finger pulse oximeter for use in ... pulse oximeter plugs into a telemedicine hub or kiosk ... pulse rate in pediatric to adult patients. The Model ...
(Date:8/28/2014)... , Aug. 28, 2014   Edison ... today announced a worldwide search for product ideas ... senior population.  Promising ideas uncovered through the 6-month ... leading medical device manufacturers and healthcare retailers with ... the lives of individuals age 65 and older. ...
Breaking Medicine Technology:Ebola vaccine trials fast-tracked by international consortium 2Ebola vaccine trials fast-tracked by international consortium 3Ebola vaccine trials fast-tracked by international consortium 4Ebola vaccine trials fast-tracked by international consortium 5Ebola vaccine trials fast-tracked by international consortium 6Ebola vaccine trials fast-tracked by international consortium 7Nonin Medical Announces FDA Clearance of Nonin Model 3231 USB Pulse Oximeter 2Edison Nation Medical Launches Open Innovation Search to Uncover Innovative Senior Care Products 2Edison Nation Medical Launches Open Innovation Search to Uncover Innovative Senior Care Products 3
... Neurologics Division of Ortho-McNeil-Janssen Pharmaceuticals, Inc., today announced ... ® (topiramate) 100mg Tablets.  These two lots ... in the U.S. and Puerto Rico.  While the ... , the company believes there are fewer than ...
... (Nasdaq: CDXS ) today announced the company will ... 2011 at 4:30 p.m. Eastern Time to discuss its first ... 2011.  The call and webcast will follow the release of ... of the call will be available approximately one hour after ...
Cached Medicine Technology:Ortho-McNeil Neurologics Voluntarily Recalls Two Lots of TOPAMAX® 2Ortho-McNeil Neurologics Voluntarily Recalls Two Lots of TOPAMAX® 3Ortho-McNeil Neurologics Voluntarily Recalls Two Lots of TOPAMAX® 4Ortho-McNeil Neurologics Voluntarily Recalls Two Lots of TOPAMAX® 5
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
Medicine Products: