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Transplanted Pancreatic Tissue Could Help Diabetics

days (within the time frame they had previously determined) exhibited a markedly reduced immune response. Next, the team tried the experiment on mice with fully functioning immune systems, but destroyed the insulin-producing cells in their pancreases before proceeding with the transplant. With the aid of relatively mild immune suppression protocols, the implanted tissues were fully functional over time, producing insulin and maintaining the mice's blood sugar at normal levels.

"The results of this study," says Reisner, "warrant further, pre-clinical research on primate models."

Contact: Jennifer Manning

jennifer@acwis.org

212-895-7952

American Committee for the Weizmann Institute of Science

Source: Eurekalert
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