Navigation Links
Transplant helps diabetes

Type I diabetes, is a type of disease, that requires insulin injections daily. Researchers are slowly heading towards closer to a cure for this disease. Some medical research centers in the U.S. and Europe conducted experiments on people with severe Type I diabetes by transplanting insulin-producing islet cells combined with less toxic antirejection drugs. These people are able to live normal lives without insulin.

A.M. James Shapiro, MD, a Canadian surgeon, director of the clinical islet and pancreas transplant programs at the University of Alberta in Edmonton , pioneered this technique called the Edmonton Protocol.//

After one year, the follow-up data of the subjects showed positive and welcoming results. The results showed that out of 15 people with type I diabetes who have undergone this technique, two-thirds of them were insulin-free.These findings were recently presented by Shapiro, at the annual meeting of the American Diabetes Association in Philadelphia.

Other researchers and Shapiro's team are currently working on improving the protocol mainly by developing better immunosupressing, antirejection drugs that are less toxic to islet cells. Since islets are considered foreign to the host, drugs have to be used to prevent the body from rejecting the cells.Sometimes these may cause further kidney problems in individuals with long-standing diabetes.

People with Type I diabetes either do not make any insulin or only make tiny amounts. Hence, they require daily shots of insulin to live. This type of disease often leads to life-threatening complications such as blindness, kidney failure, and heart disease. The Edmonton protocol has been replicated successfully in centers in the U.S. and Europe.

Another opiton is a whole pancreas transplant which will eliminate the need of insulin injections. Since only a few thousand pancreases are donated in the U.S. each year, the operation is cumbersome.

Shapiro feels that patients do much better with Edmonton protocol than transplants. Another hurdle on the road toward a cure is that there are not enough islet cells to go around. The Edmonton technique actually requires islet cells from two donor pancreases for each patient transplanted. Shapiro feels that since there is tremendous excitement with stem cell research, they suggested that islet cells could be easily replicated in the lab, and hence there would be a limitless source of cells.

Shapiro feels that if this can become the truth, there can be a permanent cure for type I diabetes patients as well as type II diabetes.


'"/>




Related medicine news :

1. Stem Cell Transplants May Be Effective For MS Patients
2. Drugs Deter Heart Disease for Transplant Patients
3. Better Drug for Heart Transplant
4. Kidney Failure after Non-Kidney Transplants
5. Measles Risk in Transplant Patients
6. Transplants Help Liver Cancer Patients
7. Steroid-Free Liver Transplants
8. Pancreas Transplant for Diabetics
9. Reducing The Risk Of Fractures After a Heart Transplant
10. A Urine Test Could Predict Rejection In Transplant Patients
11. Thawed Ovarian Transplant
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/25/2016)... ... 2016 , ... Experts from the American Institutes for Research ... June 26-28, 2016, at the Hynes Convention Center in Boston. , AIR experts ... planning, healthcare costs and patient and family engagement. , AIR researchers will be ...
(Date:6/25/2016)... ... ... of Bruton Memorial Library on June 21 due to a possible lice infestation, as reported ... head lice: the parasite’s ability to live away from a human host, and to infest ... in the event that lice have simply gotten out of control. , As lice are ...
(Date:6/25/2016)... ... June 25, 2016 , ... First Choice Emergency Room , the largest ... as the Medical Director of its new Mesquite-Samuell Farm facility. , “We are ... Mesquite location,” said Dr. James M. Muzzarelli, Executive Medical Director of First Choice Emergency ...
(Date:6/25/2016)... ... June 25, 2016 , ... Dr. Calvin ... injury. Recently, he has implemented orthobiologic procedures as a method for treating his ... of the first doctors to perform the treatment. Orthobiologics are substances that orthopaedic ...
(Date:6/25/2016)... ... June 25, 2016 , ... Conventional wisdom preaches the benefits ... terms of the latter, setting the bar too high can result in disappointment, perhaps ... slow progress toward their goal. , Research from PsychTests.com reveals that ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... N.J. , June 24, 2016  Collagen ... the design, development and manufacturing of collagen and ... regeneration announced today that Bill Messer ... and Marketing to further leverage the growing portfolio ... medical devices. Bill joins the Collagen ...
(Date:6/24/2016)... 2016   Bay Area Lyme Foundation , ... Center for Tick Borne Illness , Harvard Medical ... Hacking Medicine, University of California, Berkeley, and the ... five finalists of Lyme Innovation , the ... 100 scientists, clinicians, researchers, entrepreneurs, and investors from ...
(Date:6/24/2016)... DUBLIN , June 24, 2016 ... addition of the "Structural Electronics 2015-2025: Applications, ... In-Mold Electronics, Smart ... Integrated Photovoltaics Structural electronics involves ... as load-bearing, protective structures, replacing dumb structures such ...
Breaking Medicine Technology: