Navigation Links
Transplant helps diabetes

Type I diabetes, is a type of disease, that requires insulin injections daily. Researchers are slowly heading towards closer to a cure for this disease. Some medical research centers in the U.S. and Europe conducted experiments on people with severe Type I diabetes by transplanting insulin-producing islet cells combined with less toxic antirejection drugs. These people are able to live normal lives without insulin.

A.M. James Shapiro, MD, a Canadian surgeon, director of the clinical islet and pancreas transplant programs at the University of Alberta in Edmonton , pioneered this technique called the Edmonton Protocol.//

After one year, the follow-up data of the subjects showed positive and welcoming results. The results showed that out of 15 people with type I diabetes who have undergone this technique, two-thirds of them were insulin-free.These findings were recently presented by Shapiro, at the annual meeting of the American Diabetes Association in Philadelphia.

Other researchers and Shapiro's team are currently working on improving the protocol mainly by developing better immunosupressing, antirejection drugs that are less toxic to islet cells. Since islets are considered foreign to the host, drugs have to be used to prevent the body from rejecting the cells.Sometimes these may cause further kidney problems in individuals with long-standing diabetes.

People with Type I diabetes either do not make any insulin or only make tiny amounts. Hence, they require daily shots of insulin to live. This type of disease often leads to life-threatening complications such as blindness, kidney failure, and heart disease. The Edmonton protocol has been replicated successfully in centers in the U.S. and Europe.

Another opiton is a whole pancreas transplant which will eliminate the need of insulin injections. Since only a few thousand pancreases are donated in the U.S. each year, the operation is cumbersome.

Shapiro feels that patients do much better with Edmonton protocol than transplants. Another hurdle on the road toward a cure is that there are not enough islet cells to go around. The Edmonton technique actually requires islet cells from two donor pancreases for each patient transplanted. Shapiro feels that since there is tremendous excitement with stem cell research, they suggested that islet cells could be easily replicated in the lab, and hence there would be a limitless source of cells.

Shapiro feels that if this can become the truth, there can be a permanent cure for type I diabetes patients as well as type II diabetes.


'"/>




Related medicine news :

1. Stem Cell Transplants May Be Effective For MS Patients
2. Drugs Deter Heart Disease for Transplant Patients
3. Better Drug for Heart Transplant
4. Kidney Failure after Non-Kidney Transplants
5. Measles Risk in Transplant Patients
6. Transplants Help Liver Cancer Patients
7. Steroid-Free Liver Transplants
8. Pancreas Transplant for Diabetics
9. Reducing The Risk Of Fractures After a Heart Transplant
10. A Urine Test Could Predict Rejection In Transplant Patients
11. Thawed Ovarian Transplant
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:2/19/2017)... Charleston, South Carolina (PRWEB) , ... February 19, 2017 , ... ... class of evening undergraduate nursing students, is being led by Amelia Joseph, Ph.D. Joseph ... direct the initial operations of the nursing department in early 2016. After a nation-wide ...
(Date:2/19/2017)... (PRWEB) , ... February 19, 2017 , ... ProBrand Glitch is a set of 30 ... ProBrand Glitch users can easily reveal any logo with a glitch reveal in just a ... control over the style and animation of each preset. Use these presets to add a ...
(Date:2/19/2017)... ... February 19, 2017 , ... ... healthcare, will join forces with Healthwise ® at HIMSS 2017 ... industry leader in evidence-based health education, technology and services, will demonstrate a voice-powered ...
(Date:2/18/2017)... ... February 17, 2017 , ... Focused start-ups, not ... the industry, according to the recent NEJM Catalyst Insights Report on the New ... NEJM Catalyst Insights Council, a qualified group of U.S. executives, clinical leaders, and ...
(Date:2/18/2017)... ... February 17, 2017 , ... ... drvallecillos.com , Beverly Hills plastic surgeon Dr. Glenn Vallecillos experiments ... Dr. Vallecillos says, "Traditionally, plastic surgery has been centered around that idea that ...
Breaking Medicine News(10 mins):
(Date:2/20/2017)... 21, 2017 Taiwan Biophotonic Co. (tBPC), a ... vital signs sensing solutions, today announced the CE Marking ... pulse oximeter, the oCare TM Pro 100, which is ... medical devices space.  tBPC,s Wrist Pulse Oximeter, ... simple and reliable method to measure and record heart ...
(Date:2/20/2017)... , Feb. 20, 2017 Provides understanding ... agreements entered into by the worlds leading healthcare ... Description The Global Anemia Partnering Terms ... access to partnering deals and agreements entered into ... - Trends in partnering deals - Top ...
(Date:2/20/2017)... , Feb. 20, 2017  This Report analyzes the worldwide ... Dosage Forms: Injectables, Solid Dosage Forms, and Liquid & Semi-solid Dosage ... Canada , Japan , ... World. Read the full report: http://www.reportlinker.com/p04707109-summary/view-report.html ... Annual estimates ...
Breaking Medicine Technology: