Navigation Links
Transdermal HRT not cardioprotective in postmenopausal women with Coronary Artery Disease

Transdermal hormone replacement therapy (HRT) does not reduce the risk of cardiac events in postmenopausal women with existing coronary artery disease (CAD). In the PHASE trial (Papworth HRT Atherosclerosis Study), researchers randomized 255 postmenopausal women with angiographically proven coronary artery disease to receive either transdermal HRT--17-beta-estradiol with or without cyclic norethisterone--or no hormone replacement therapy. The women were followed for 4 years. Overall, 134 women received hormone replacement therapy. Of these, 58 had had a previous hysterectomy. The other 121 women served as controls.

On intention-to-treat analysis, there was no statistical difference in the incidence of unstable angina requiring hospitalization, MI or premature death from heart disease in women receiving HRT and women not receiving the therapy. Respectively, the average event rates were 15.6 and 12.6 per 100 patient-years. Results from the PHASE study also seem to indicate an increased risk of thromboembolic complications, such as stroke, with HRT. This observation is supported by results from the HERS study, a randomized trial carried out in the US that included 3000 women, and was designed to assess the cardioprotective effect of combined HRT in women with documented CAD.

It may therefore be appropriate that women with proven coronary artery disease should not commence HRT. Nevertheless, women receiving HRT for more than 2 years should continue.
'"/>




Page: 1

Related medicine news :

1. Transdermal HRT not cardioprotective in postmenopausal women with CAD
2. Transdermal Vaccine Effective in Treating Alzheimers Disease in Mice
3. Transdermal HRT not cardioprotective in postmenopausal women with CAD
4. Transdermal HRT not cardioprotective in postmenopausal women with CAD
5. Enlarged waistline may predict atherogenesis for postmenopausal women
6. Research explains why postmenopausal women accumulate abdominal fat.
7. Testosterone Therapy can improve sexual function in postmenopausal women
8. Transdermal HRT not cardioprotective in postmenopausal women with CAD
9. Starvation in pregnant women can cause heart disease to their children
10. Brisk Walking lowers memory loss in women
11. Young womens woes
Post Your Comments:
(Date:7/24/2014)... Primary care treatment of overweight and obese preschoolers works ... to when only the child is targeted, according to ... conducted at the University at Buffalo and Women and ... were overweight or obese and had one parent who ... obese, according to body mass index (BMI) measurements, calculated ...
(Date:7/24/2014)... or more equally positive outcomes experience paradoxical feelings ... in different regions of the brain, according to ... scholar at the Princeton Neuroscience Institute at Princeton ... rated the desirability of more than 300 products ... images of paired products with different or similar ...
(Date:7/24/2014)... In signing the Workforce Innovation and ... Atlanta BeltLine Workforce Partnership in Healthcare as one ... ( http://www.whitehouse.gov/ready-to-work ). The Administration called for ... economic strategy and profiled successful local efforts to ... Obama highlights the power of partnerships in Atlanta,” ...
(Date:7/24/2014)... 24, 2014 In a recent report by ... officially put an end to criminal penalties associated with possession ... era for marijuana reform in Washington DC, giving it one ... law replaces criminal penalties for possession of one ounce of ... the possession of more than an ounce of marijuana remain ...
(Date:7/24/2014)... 2014 According to market research ... Technology Roadmap, Forecasts and Analysis - 2018", the ... to reach $7.7 billion by 2018 at a ... 102 market data tables and 30 figures spread ... Mapping Market: Global Advancements, Business Models, Technology Roadmap, ...
Breaking Medicine News(10 mins):Health News:Overweight and obese preschoolers lose more weight when parent is also treated 2Health News:Overweight and obese preschoolers lose more weight when parent is also treated 3Health News:Brain's dynamic duel underlies win-win choices 2Health News:Brain's dynamic duel underlies win-win choices 3Health News:President Cites Atlanta BeltLine Workforce Partnership in Healthcare as National Model 2Health News:President Cites Atlanta BeltLine Workforce Partnership in Healthcare as National Model 3Health News:President Cites Atlanta BeltLine Workforce Partnership in Healthcare as National Model 4Health News:President Cites Atlanta BeltLine Workforce Partnership in Healthcare as National Model 5Health News:Washington D.C. Decriminalizes Marijuana 2Health News:3D Mapping & 3D Modeling Market Projected to $7.7 Billion by 2018 - Report by MarketsandMarkets 2Health News:3D Mapping & 3D Modeling Market Projected to $7.7 Billion by 2018 - Report by MarketsandMarkets 3Health News:3D Mapping & 3D Modeling Market Projected to $7.7 Billion by 2018 - Report by MarketsandMarkets 4
... HUM ) has,recently released three of its Stay Smart, Stay Healthy ... Stay Healthy videos have racked up more than 1.1 million,hits on ... remained,in the Top 5 videos in education worldwide through December. The ... , "We developed the Stay Smart, Stay ...
... the DNC bolsters firm,s national government affairs practiceWASHINGTON, ... nationally recognized political figure, presidential candidate and six ... an independent consultant exclusive to the government affairs ... Governor Dean will provide guidance to clients, particularly ...
... Than Half of America,s Youth Exceed Recommended Fat Intake; ... Makeover QUINCY, Mass., March 3 Continuing its tradition ... has expanded its NutriFilter sorting feature to include ... program recently launched at sister companies, Stop & ...
... genders regardless of weight issues, study finds , , TUESDAY, March ... than two hours a day or are otherwise inactive have ... , Researchers looked at more than 3,000 children whose ... age. , Each year, parents were asked about any ...
... Each day we have countless conversations with ourselves, and if ... what we say to ourselves is critical, judgmental, and often ... get it, we tend to make excuses and blame others, ... to our assumed shortcomings. Carol Messmer,s new ...
... 3 Catalyst Pharmaceutical Partners, Inc. (Nasdaq: ... develops and commercializes prescription drugs for the treatment of ... product development program. In order to extend its ... halt enrollment of new subjects into its ongoing U.S. ...
Cached Medicine News:Health News:Humana Releases Stay Smart, Stay Healthy Videos in Spanish 2Health News:Howard Dean to Join McKenna Long and Aldridge LLP 2Health News:Howard Dean to Join McKenna Long and Aldridge LLP 3Health News:Peapod Expands NutriFilter Shopping Tool With Healthy Ideas Program 2Health News:Peapod Expands NutriFilter Shopping Tool With Healthy Ideas Program 3Health News:2 Hours Glued to TV Doubles Kids' Asthma Risk 2Health News:'Conversations with Self: Discovering the Power of Your Inner Voice': Discover How to Find and Listen to an Inner Voice That Is Encouraging and Helpful 2Health News:Catalyst to Focus Resources on its Lead Indication for CPP-109; Cocaine Addiction 2Health News:Catalyst to Focus Resources on its Lead Indication for CPP-109; Cocaine Addiction 3
(Date:7/24/2014)... 24, 2014  Uroplasty, Inc. (NASDAQ: UPI ... and markets innovative proprietary products to treat voiding ... 2015 first quarter ended June 30, 2014.  ... Neuromodulation System grew 19% to $4.1 million, as ... of the prior year.  Total revenue for the ...
(Date:7/24/2014)... 24, 2014 Omnicell, Inc. (NASDAQ: ... and supply management solutions and analytics software for ... 31, to discuss the Company,s Second Quarter 2014 ... 2014 earnings conference call and webcastWhen: , ... Lipps, chairman, president and chief executive officer ...
(Date:7/24/2014)... 24, 2014  Alimera Sciences, Inc. (NASDAQ: ... the research, development and commercialization of prescription ophthalmic pharmaceuticals, ... of fiscal year 2014 financial results after the market ... call will follow on the same day at 4:30 ... be hosted by Dan Myers , President and ...
Breaking Medicine Technology:Uroplasty Reports Fiscal First Quarter Results 2Uroplasty Reports Fiscal First Quarter Results 3Uroplasty Reports Fiscal First Quarter Results 4Uroplasty Reports Fiscal First Quarter Results 5Uroplasty Reports Fiscal First Quarter Results 6Uroplasty Reports Fiscal First Quarter Results 7Uroplasty Reports Fiscal First Quarter Results 8Uroplasty Reports Fiscal First Quarter Results 9Uroplasty Reports Fiscal First Quarter Results 10Uroplasty Reports Fiscal First Quarter Results 11Omnicell to Release Second Quarter 2014 Earnings Results on July 31 2Alimera Sciences To Release Second Quarter 2014 Results 2
... A new approach to unblocking heart arteries minimally invasively ... and less risk overall, particularly for obese patients, according ... Symposium on Endovascular Therapy (ISET). Every year, about one ... open their blocked arteries. New data suggests that beginning ...
... Excalibur, the international,investment house specialising in medical ... to deliver pioneering stem cell treatments if it ... , Professor Sir Christopher ... that ReNeuron plc has received approval from the ...
Cached Medicine Technology:Wrist Access Safer, Easier for Many Patients Undergoing Minimally Invasive Treatment of Blocked Heart Arteries 2UK Must Maintain its Momentum in Stem Cell Expertise 2
Head-worn Loupe G3, Galilean teleloupe system....
... The XL Advantage delivers higher magnification for ... crisp, true image, even at the highest ... edge clarity and precise color rendition is ... with an anti-reflective coating produce a superior ...
... up of doublet objective and high power ... and 3.0x. The true benefit of this ... maintaining focal clarity is made possible due ... ultra lightweight aluminum bar and individual interpupillary ...
Used for maintaining and forming the anterior chamber by the injection and removal of fluids, air miotics, and viscoeastic substances, as well as keeping the cornea moist during surgery. 4 mm from be...
Medicine Products: