Navigation Links
Trails to detect effective breast cancer drugs that reduces recurrences

A quest for new drug has started to determine and help patients to have a recurrence free survival after breast cancer surgery. The chemotherapy drugs docetaxel (Taxotere) and vinorelbine (Navelbine) are tested to analyze the outcomes.//

It was previously reported by the Finnish researchers that patients who received infusions of trastuzumab (Herceptin) were less likely to get recurrences in the New England Journal of Medicine.

Dr. Heikki Joensuu, corresponding author and a physician at Helsinki University Central Hospital said that the breast cancer recurrence reduced by 42% during the first 3 years of follow-up among women treated with docetaxel when compared to those who received vinorelbine.

But on the other hand it was found that docetaxel was associated with more adverse effects such as allergic reactions, swelling and fever.

Joensuu and his colleagues conducted a study in more than a thousand women with breast cancer.

They gave them three cycles of either docetaxel or vinorelbine, followed by three cycles of other cancer drugs.

Then, a subgroup of 232 women was identified whose tumors had an amplified HER2/neu gene. This gene is known to be associated with cancers that grow and spread aggressively.

They were also assigned either to receive nine weeks of infusions of Herceptin or a placebo. By doing this the researchers were able to identify the best regime for recurrence-free survival.

The result of the study was that patients who received Herceptin had 58 % fewer cancer recurrences during the three-year follow-up than those who didn't get the drug. Previous studies also show that adjuvant trastuzumab [Herceptin] if taken for a course of one year reduces the rate of breast cancer recurrence by 50 % in women having HER2-positive breast cancer.

But it is not clearly understood about the optimal duration of the drug usage. Dr. Mark Pegram, director of the women's cancer pr ogram at the Jonsson Cancer Center at the David Geffen School of Medicine at UCLA said that if it is the short nine week regime that turns out to be ideal then it is great news. But still this question remains to be confirmed.


'"/>




Related medicine news :

1. Clinical Renal Trails Do Not Have Sufficient Women Participants
2. Clinicians Participating In the Pharmaceutical-Sponsored Trails Tend To Prescribe Their Drugs
3. CDC To Conduct Pre-clinical Trails Of BioDiems Intranasal Bird Flu Vaccine
4. Vitamin B12 can help in detecting cancers
5. “Brain fingerprinting”- The new lie detectr
6. Ductal lavage may detect early breast cancer
7. Better prostate cancer detection
8. Early detection of prostate cancer
9. Early detection of heart attack
10. Cytobrush to detect oral cancer
11. New device for detecting artery blockages
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/26/2016)... ... 26, 2016 , ... Brent Kasmer, a legally blind and certified personal trainer is helping to ... app. The fitness app plans to fix the two major problems leading the fitness industry ... fits all type program , They don’t eliminate all the reasons people quit ...
(Date:6/25/2016)... Viejo, California (PRWEB) , ... June 25, 2016 , ... ... to fit their specific project," said Christina Austin - CEO of Pixel Film Studios. ... fully customizable and all within Final Cut Pro X . Simply select a ...
(Date:6/25/2016)... (PRWEB) , ... June 25, 2016 , ... Conventional wisdom ... of success. In terms of the latter, setting the bar too high can result ... more than just slow progress toward their goal. , Research from PsychTests.com ...
(Date:6/24/2016)... ... 24, 2016 , ... The Pulmonary Hypertension Association (PHA) learned ... receive two significant new grants to support its work to advance research and ... by recognizing patients, medical professionals and scientists for their work in fighting pulmonary ...
(Date:6/24/2016)... ... June 24, 2016 , ... People across the U.S. are sharpening their pencils ... an essay contest in which patients and their families pay tribute to a genetic ... 2016 National Society of Genetic Counselors (NSGC) Annual Education Conference (AEC) this September. ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... , June 24, 2016  Consumers have ... and regulators/payers have placed more emphasis on patient ... patient support programs in the pharmaceutical industry have ... medications. Consequently, pharmaceutical companies are focusing on becoming ... are providing products and services that improve health. ...
(Date:6/24/2016)... , June 24, 2016  Global Blood Therapeutics, ... company developing novel therapeutics for the treatment of ... announced the closing of its previously announced underwritten ... at the public offering price of $18.75 per ... were offered by GBT. GBT estimates net proceeds ...
(Date:6/24/2016)... 2016 Dublin ... addition of the " Global Markets for Spectroscopy ... This report focuses on the ... review, including its applications in various applications. The report ... includes three main industries: pharmaceutical and biotechnology, food and ...
Breaking Medicine Technology: