Navigation Links
Timing Of Women's Labor May Determine Effectiveness Of Pain Medication

It has now been found out that women who had day labor got longer pain relief than women with night labor with the same amount of labor pain medicine. This could be due to the impact of natural daily body rhythms // that may influence the effectiveness of spinal-epidural pain medication for women in labor.

Therefore the time of administration of the medication is regarded to be an important factor in determining its effectiveness. In the future, doctors may consider time of day, as well as patient's weight and other factors, when determining the best dose or method of drug delivery. The study's goal was to determine if the body's natural internal rhythms can affect the effectiveness of pain medication for laboring women. The study, involved 77 women who were in labor with their first babies and requested spinal-epidural pain medication.

The biological rhythms studied include the circadian rhythm, the 24-hour body clock, and the ultradian rhythm, shorter-than-24-hour-cycles, which determine sleeping and eating patterns and can also affect blood pressure, heart rate and body temperature. Some rhythms are controlled by sunlight and others are controlled internally.

The researchers found that women who labored between noon and 6 p.m. got an average of 27 percent longer pain relief from a single dose of the spinal-epidural medication fentanyl than women whose labor was between 8 p.m. and 2 a.m. This is one of the first studies to examine whether there are chronobiological variations in the effectiveness of a drug for labor pain relief.

Knowing more about how time of administration influences the drug's effects could have significant practical implications for how it is prescribed and delivered. For example, the dose could be tailored to the time of day or a smart, programmable, time-released version of the drug could be developed to optimize desired drug effects and minimize undesired side effects both for women in labor and pati ents with other pain syndromes.

Furthermore, the right treatment given at the wrong time can be ineffective or create a crisis of escalating toxicity. Conversely, even a weak treatment, if given at the right moment, could prove surprisingly effective.


'"/>




Related medicine news :

1. Optimum Timing for HIV/AIDS Prognosis
2. Drink till you drop dead in English Pubs- Restriction on Timings Lifted
3. Minimally Invasive Lung Cancer Surgery Minimize the Treatment Timings
4. Timing of Food Consumption Activates Genes in Specific Brain Area
5. Study on Timing of Spinal Surgery
6. Breast Cancer Risk Influenced by the Timing of Weight Gain
7. Timing of First Intercourse is Vital
8. Timing – Crucial for Asthma Drugs to Wor
9. Unsatisfactory Grade On Womens Health Issues
10. Womens strong sense of smell
11. Womens stroke indications vary from mens
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:2/22/2017)... ... February 22, 2017 , ... A cylindrical “pipeline” ... sometimes harder to reach ones, according to the results of a clinical trial ... in Houston by Ricardo A. Hanel, MD, PhD, neurovascular surgeon with Baptist Health ...
(Date:2/22/2017)... ... ... Sideline Products participated in the World Horse Expo held in Timonium, MD ... production crew. Tom Seay’s program “Best of America by Horseback” is broadcasted on ... be featured on April 6, 2017. After the broadcast, the clip will be posted ...
(Date:2/22/2017)... ... ... Using the power of the internet, IdrisArkette.com has managed to produce more ... just 24 months, thousands of individuals interested in a medical procedure managed to be ... is not getting quieter. In fact it’s becoming noisier by the day. If you ...
(Date:2/22/2017)... ... , ... ANGLESTRONG , the new recovery management app with multiple innovative ... Store and Google Play . Florida-based Sober Network, Inc., the premier provider ... with Angle to build ANGLESTRONG. The new recovery management app is a passion project ...
(Date:2/22/2017)... ... February 22, 2017 , ... Becker’s Spine Review, the ... featuring Michigan neurosurgeon Jay Jagannathan, M.D., as a “Spine Surgeon to Know.” ... neurosurgeons in Michigan performing minimally invasive back surgery that often results in less ...
Breaking Medicine News(10 mins):
(Date:2/22/2017)... astic drugs develop from traditional single antineoplastic drug towards ... at multiple links. Research and development of antineoplastic drugs ... Download the full report: https://www.reportbuyer.com/product/4696059/ ... new tumors in China every ... industrialization and lifestyles changed by factors like urbanization, malignant ...
(Date:2/22/2017)... Feb. 22, 2017 Summary Provides ... deals and agreements entered into by the worlds leading ... Description The Global Motor Neurone Disease Partnering ... access to partnering deals and agreements entered into by ... in partnering deals - Top deals by value ...
(Date:2/22/2017)... , Feb. 22, 2017  Corin Group announced ... a device used to treat patients with both a ... shoulder arthritis. The condition, known as cuff tear arthropathy, ... shoulder. The Humelock Reversed Shoulder System, ... extremities technology company based near Lyon, France ...
Breaking Medicine Technology: