Navigation Links
Tigecycline – New Generation Tetracycline With Broad Spectrum Antibacterial Activit

Richard Wenzel and his colleagues from United Kingdom have found a new antibiotic tigecycline which belongs to the family of new generation of Tetracycline known as Glycycline. //

Due to indiscriminate use of antibiotics there is an increased incidence of antibiotic resistance shown by many organisms. Staphylococcus aureus is a gram positive bacteria, which is a major cause of concern as it causes most of the nosocomial infections in hospital. Staphylococcus aureus as shown an increased resistance to many drugs including the different analogues of Tetracycline and Vancomycin.

Drug – Tetracycline: Tetracyclines were first discovered 50 years ago and were found to have broad spectrum antibacterial activity against both gram positive and gram negative bacteria. Following their initial widespread use, a high incidence of tetracycline resistance among many bacteria has led to tetracyclines being relegated to second- or third-line therapy. As increases resistance to tetracycline have developed there are lot of approaches to restore the potential of tetracyclines as broad-spectrum antibiotics, systematic searches for tetracycline analogues with activity against both tetracycline-susceptible and tetracycline-resistant organisms were performed in the early 1990s which has led to the identification of the glycylcyclines, including tigecycline.

Properties of Tigecycline: Tigecycline was discovered by introducing substituents at position 9 of minocycline resulted in compounds that not only had activity typical of earlier tetracyclines, but also displayed activity against bacteria containing resistant genes.

Tigecycline inhibits bacterial protein synthesis by binding to the 30S ribosomal subunit. Tigecycline blocks entry of amino-acyl tRNA molecules into the A site of the ribosome, preventing incorporation of amino-acid residues into elongating peptide chains. Tetracycline drug resistance in bacteria occurred due to
'"/>




Page: 1 2

Related medicine news :

1. Hearing Problems Of Middle Age Are Affecting The Younger Generation
2. Newer Generation Sleeping Pills Lack Superior Performance
3. New Generation Clinical Trials Could Save Time And Money, Improve Patient Care
4. Moles Among The Older Generation May Be Dangerous
5. Leptin, The Next Generation Antidepressant?
6. Generation Scotland To Examine Relation Between Lifestyle, Genetics and Health
7. Baby Gloom: ‘Baby Gap’ Generation Signals Babies’ Days Ot!
8. Researchers Aim To Develop Next Generation Of Surgical Robots
9. New Generation Teenagers Addiction to Prescription Drugs
10. New Generation - Medicinal Products
11. Take Third Generation Oral Contraceptives Off the Shelves-consumer Group Insists
Post Your Comments:
(Date:9/30/2014)... published in the October 2014 issue of The ... cancer as easy as a simple blood test. This test, ... detect some cancers earlier than ever before, but it may ... as identify those more likely to develop cancer in the ... so helping to save peoples, lives," said Diana Anderson, a ...
(Date:9/30/2014)... Doheny HealthDay Reporter , ... are given broad-spectrum antibiotics before the age of 2 ... during childhood, new research suggests. Broad-spectrum antibiotics target ... to the study. "It is a reason to ... you are picking," said lead researcher Dr. Charles Bailey, ...
(Date:9/30/2014)... September 30, 2014 Visit Pam and ... Hill and you will find a loving couple facing ... Lateral Sclerosis. , Steve was diagnosed with ... Gehrig’s Disease – just before the couple’s second wedding ... , A new video, “Care, Support & ALS,” ...
(Date:9/30/2014)... September 30, 2014 TrailMyx.com —the ... October Flavor of the Month: raw pumpkin seeds. , ... of squash”)—are rich in protein, and valued by experts ... multiple types of vitamin E. They are prized for ... and proper bowel function. , Of course, pumpkin seeds ...
(Date:9/30/2014)... Charlotte, NC (PRWEB) September 30, 2014 ... corporations and caring individuals, National Children’s Oral ... than $150,000 in grants to non-profit clinical ... NCOHF Affiliate Network and deliver comprehensive educational, ... , Recipients include:, ...
Breaking Medicine News(10 mins):Health News:New blood test determines whether you have or are likely to get cancer 2Health News:Antibiotic Use Before Age 2 Might Raise Obesity Risk, Study Says 2Health News:Antibiotic Use Before Age 2 Might Raise Obesity Risk, Study Says 3Health News:Hospice Provides Care and Support to Patients and Family Caregivers with ALS 2Health News:TrailMyx.com Features October Flavor of the Month 2Health News:America's ToothFairy Awards More Than $150,000 in Grants to Save Young Smiles 2Health News:America's ToothFairy Awards More Than $150,000 in Grants to Save Young Smiles 3
... Davenport-Ennis, National Patient Advocate Foundation President, CEO and ... Enhance Patient CareWASHINGTON, Jan. 29 Speaking on ... in the United States, National Patient Advocate Foundation ... and Founder Nancy Davenport-Ennis was invited to testify ...
... 29 Houlihan Smith,& Company, Inc. (Houlihan) completed advisory ... Health) as announced by,Charles Botchway, Group Managing Director and ... by Houlihan Smith Managing Director Reginald,McGaugh. Terms of the ... "We have been working with Mr. McGaugh and his ...
... Meditation Center of Los Angeles will present a program featuring ... an ancient practice of physical fitness, which has been used ... youthfulness in the body. The Level 1 & 2 ... Center for the Arts in Eagle Rock.The healing Taoist practice ...
... at Washington University School of Medicine in St. Louis ... in a low-oxygen, or hypoxic, environment. , They believe ... stroke, heart attack and cancer. Sensitivity to low oxygen ... The researchers report their findings in the Jan. 30 ...
... Jan. 29 /PRNewswire-Asia-FirstCall/ -- Genesis,Pharmaceuticals Enterprises, Inc. ... a U.S. pharmaceutical company with its principal ... announced that Laiyang Jiangbo,Pharmaceutical Co., Ltd. ("Laiyang"), ... an Assets Transfer Contract (the "Contract") with,Shandong ...
... (ERT), (Nasdaq: ERES ), a leading provider ... services to the pharmaceutical, biotechnology, medical device, and related ... Company,s President and Chief Executive Officer, is scheduled to ... at 2:00 p.m. EST on February 10, 2009 at ...
Cached Medicine News:Health News:National Patient Advocate Foundation Founder Testifies Before U.S. Senate Health Committee on Methods to Improve Healthcare Quality and Patient Outcomes 2Health News:National Patient Advocate Foundation Founder Testifies Before U.S. Senate Health Committee on Methods to Improve Healthcare Quality and Patient Outcomes 3Health News:National Patient Advocate Foundation Founder Testifies Before U.S. Senate Health Committee on Methods to Improve Healthcare Quality and Patient Outcomes 4Health News:Houlihan Smith Arranges Equity Investment Into Tri-Tech Health, LLC 2Health News:World-renowned Instructor of the Healing Practice of Qigong to Teach in Los Angeles Mar. 7 & 8 2Health News:Worm provides clues about preventing damage caused by low-oxygen during stroke, heart attack 2Health News:Worm provides clues about preventing damage caused by low-oxygen during stroke, heart attack 3Health News:Genesis Pharmaceuticals Enters Into Agreement to Purchase Hongrui Pharmaceuticals, and Acquire 22 New Traditional Chinese Medicines 2Health News:Genesis Pharmaceuticals Enters Into Agreement to Purchase Hongrui Pharmaceuticals, and Acquire 22 New Traditional Chinese Medicines 3Health News:Genesis Pharmaceuticals Enters Into Agreement to Purchase Hongrui Pharmaceuticals, and Acquire 22 New Traditional Chinese Medicines 4Health News:Genesis Pharmaceuticals Enters Into Agreement to Purchase Hongrui Pharmaceuticals, and Acquire 22 New Traditional Chinese Medicines 5Health News:eResearchTechnology, Inc. to Present at the UBS Global Healthcare Services Conference on February 10, 2009 2
(Date:9/30/2014)... NEWPORT BEACH, Calif. , Sept. 30, 2014 ... prestigious accreditation of the American Association of Tissue ... Russell Cook , Chief Executive Officer. ... on-site inspection by a specially trained AATB inspector.  ... and administrative performance within the facility meets or ...
(Date:9/30/2014)... -- Georgia-Pacific Professional is a leading provider of hygienic ... range of away from home applications. Building on ... including hospitals, long-term care facilities, surgical centers and ... products and solutions to the dental community. ... control in the dental office," said Sean ...
(Date:9/30/2014)... , Sept. 30, 2014 Passport Health, ... America , has launched FluFree.com, a website designed ... vaccinations. For 20 years, Passport Health has ... the flu. The launch of FluFree.com is designed to ... and the number of people who actually chose to ...
Breaking Medicine Technology:Biostructures, LLC Earns AATB Accreditation 2Georgia-Pacific Professional Brings Its Success in Medical Solutions to the Dental Community 2Georgia-Pacific Professional Brings Its Success in Medical Solutions to the Dental Community 3Passport Health Launches FluFree.com - Aims To Improve Flu Vaccination Rates and Fulfill Growing Public Health Priority 2Passport Health Launches FluFree.com - Aims To Improve Flu Vaccination Rates and Fulfill Growing Public Health Priority 3
... CAMBRIDGE, Mass. Dec. 10 The US Army, through the ... Technologies a contract to develop a robotic approach to airway ... clearing a patient,s airway and inserting a tube to maintain ... intubation, is critical as the loss of proper air circulation ...
... , TITUSVILLE, N.J., Dec. 10 Treatment with once-monthly ... CONSTA®, according to new data from a comparative study of ... clinical trial were released this week. , An estimated one ... brain disorder that impairs a person,s ability to think clearly, ...
Cached Medicine Technology:The Army Awards Follow-On Contract for Autonomous Airway Management to Energid Technologies 2Phase III Study Demonstrates INVEGA(R) SUSTENNA(TM) (paliperidone palmitate) Statistically Similar to RISPERDAL(R) CONSTA(R) (risperidone) Long-Acting Injection 2Phase III Study Demonstrates INVEGA(R) SUSTENNA(TM) (paliperidone palmitate) Statistically Similar to RISPERDAL(R) CONSTA(R) (risperidone) Long-Acting Injection 3Phase III Study Demonstrates INVEGA(R) SUSTENNA(TM) (paliperidone palmitate) Statistically Similar to RISPERDAL(R) CONSTA(R) (risperidone) Long-Acting Injection 4Phase III Study Demonstrates INVEGA(R) SUSTENNA(TM) (paliperidone palmitate) Statistically Similar to RISPERDAL(R) CONSTA(R) (risperidone) Long-Acting Injection 5Phase III Study Demonstrates INVEGA(R) SUSTENNA(TM) (paliperidone palmitate) Statistically Similar to RISPERDAL(R) CONSTA(R) (risperidone) Long-Acting Injection 6Phase III Study Demonstrates INVEGA(R) SUSTENNA(TM) (paliperidone palmitate) Statistically Similar to RISPERDAL(R) CONSTA(R) (risperidone) Long-Acting Injection 7Phase III Study Demonstrates INVEGA(R) SUSTENNA(TM) (paliperidone palmitate) Statistically Similar to RISPERDAL(R) CONSTA(R) (risperidone) Long-Acting Injection 8Phase III Study Demonstrates INVEGA(R) SUSTENNA(TM) (paliperidone palmitate) Statistically Similar to RISPERDAL(R) CONSTA(R) (risperidone) Long-Acting Injection 9Phase III Study Demonstrates INVEGA(R) SUSTENNA(TM) (paliperidone palmitate) Statistically Similar to RISPERDAL(R) CONSTA(R) (risperidone) Long-Acting Injection 10
Used to introduce balloon, electrode, closed or non-tapered end catheters and other devices for intervention....
Used to introduce balloon, diagnostic and guiding catheters, or other devices for intervention....
Used to introduce large balloon, closed and non-tapered end catheters or other devices for intervention....
Used for the introduction of catheters, balloons and other vascular devices....
Medicine Products: