Navigation Links
Three Gene Variants Could Hold Key for HIV Vaccine: Study

Three gene variants in the DNA of 486 AIDS patients appear to play a role in containing and slowing the HIV virus, according to research published Thursday.

The researchers hope their finding will lead to a vaccine that would boost the protective effects of one or more of these genes, and help the body's own immune system overcome an infection.

One gene variant looks specially promising, the scientists said in a study to appear in the Friday edition of the journal Science.

"These results not only approximately double our understanding of the factors that influence variation amongst individuals in how they control HIV-1, but also point toward new mechanisms of control," said David Goldstein, of Duke's Institute for Genome Sciences and Policy at North Carolina's Duke University and chief author of the study.

The international team of geneticists worked for 18 months in carefully selecting patients and using the latest in genome-wide screening technology to discover the three genes.

The research found that some patients with specific gene variants in key immune system cells appear to be much better controlling the proliferation of the AIDS virus after infection.

"As we expand the number of patients in future studies conducted by CHAVI (Center for HIV/AIDS Vaccine Immunology) researchers, we aim to discover even more polymorphisms that could provide additional clues how some patients are better able to control the virus than others," Goldstein said.

"This should ultimately lead to novel targets for vaccines, the primary goal of CHAVI," a seven-year project launched in 2005 by the National Institute of Allergy and Infectious Diseases (NIH).

Two of the newly discovered gene variants were found in genes controlling the human leukocyte antigen (HLA) system, which plays a "major role" in the immune system by identifying foreign invaders and "tagging" them for des
'"/>




Page: 1 2

Related medicine news :

1. One in Three Heart Attack Patients Have No Chest Pains
2. Nobel Prize for Medicine shared by Three scientists
3. Three Tropical Parasites Genetic Code Unravelled
4. The Future Pattern Of Weight Gain Is Laid As Early As Three Years Of Age
5. Smoking Increases The Risk Of Heart Disease By Three Times
6. Three Sisters Have One Baby and Make History
7. Three In One Ultrasound Probe For 3-D Imaging Of Heart And Tissue Destruction Developed
8. Three More Bird Flu Cases Reported By China
9. Three meals daily Keeps Keralas elderly Healthy
10. Three dimensional structure of apolipoprotein revealed
11. Delhi Witnessed 34 Meningitis Deaths In Three Months
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Three Gene Variants Could Hold Key for HIV Vaccine Study

(Date:12/17/2014)... -- Expectant parents should leave prenatal picture-taking to medical ... Use of ultrasound imaging and heartbeat monitors to get ... agency warns. "Although there is a lack ... and heartbeat monitors, prudent use of these devices by ... FDA biomedical engineer, said in an agency news release. ...
(Date:12/17/2014)... HealthDay Reporter , TUESDAY, Dec. 16, ... America, and work commitment is a big reason why, new ... said Dr. Mathias Basner, an assistant professor of sleep and ... of Medicine. A time-use survey of nearly 125,000 Americans, ... main activity exchanged for sleep. Short sleepers -- those who ...
(Date:12/15/2014)... 15, 2014 South Florida’s leading urgent care ... can be a daze of hassle, hustle, and bustle that ... decking halls, to burns when making special meals and heartburn ... can happen at any time. To prevent this season of ... made a list of helpful and healthful holiday tips to ...
(Date:12/15/2014)... News) -- Expert pilots process visual information more efficiently ... better decisions during landings, a new study shows. ... pilots to master, and 36 percent of all airplane ... final approach and landing. Researchers monitored the brain ... pilots while they were at the controls of a ...
(Date:12/15/2014)... 15, 2014 At the leading, long-established ... AutismOne and Focus Autism will welcome ... research on the effects of toxins to children’s health, ... information. , Luminaries such as Dr. Lucija Tomljenovic ... with esteemed, credentialed colleagues of the United States to ...
Breaking Medicine News(10 mins):Health News:FDA Warns Against Fetal 'Keepsake' Videos 2Health News:Work Steals Valuable Sleep Time, Study Finds 2Health News:Work Steals Valuable Sleep Time, Study Finds 3Health News:MD Now Urgent Care Presents Healthy Holiday Tips 2Health News:MD Now Urgent Care Presents Healthy Holiday Tips 3Health News:Study Shows Why Expert Pilots Are Experts 2Health News:AutismOne and Focus Autism Collaborate on Scientific Conference; International Group of Researchers to Present in Chicago, May 2015 2Health News:AutismOne and Focus Autism Collaborate on Scientific Conference; International Group of Researchers to Present in Chicago, May 2015 3
... AFRICA TO PRODUCE, HACHETTE AUDIO TO PUBLISH AND ... AIDS ORPHANS, LOS ANGELES, July 17 In ... a New South Africa (ANSA) announced plans,to produce an ... book of legendary tales hand-picked by the,Nobel Peace Prize ...
... Annual Great Sports,Legends Dinner to Benefit The Buoniconti Fund to Cure Paralysis ... ... Sports luminaries and philanthropy,icons will be recognized when they gather at ... York,s Waldorf=Astoria,Hotel. This year, Bob Costas has been named the Master of ...
... focused Nuclear Medicine and Molecular Imaging online community to allow medical ... evolving arena of medical imaging. , ... London, UK ... Inc, Amex: MGT) announces the launch of a focused Nuclear ...
... The Netherlands, July 17 The European,Association of ... platform,for the promotional activities for the first European ... 19 September. http://www.urologyweek.org is a,general public-oriented ... conditions and when to seek help from a ...
... NY, July 17th, 2008A new national scorecard from The ... finds that the U.S. health care system has failed ... declined significantly since the first national scorecard in 2006. ... industrialized nation, the U.S. overall continues to fall far ...
... device manufacturer focusing on minimally invasive treatment for ... company has closed a Series C financing round ... active in medical technology. The lead investors were ... were joined in the round by previous investors ...
Cached Medicine News:Health News:Nelson Mandela's Favorite African Folktales to be Produced as Audiobook Featuring Archbishop Tutu, Gillian Anderson, America Ferrera, Whoopi Goldberg, Samuel L. Jackson, Alan Rickman and Jurnee Smollett, Directed by Alfre Woodard 2Health News:Nelson Mandela's Favorite African Folktales to be Produced as Audiobook Featuring Archbishop Tutu, Gillian Anderson, America Ferrera, Whoopi Goldberg, Samuel L. Jackson, Alan Rickman and Jurnee Smollett, Directed by Alfre Woodard 3Health News:Sports Luminaries Andre Agassi, Jerry Rice, Scottie Pippen, Helio Castrovenes, Richard 'Goose' Gossage Among Those Named 2008 'Great Sports Legends' 2Health News:Sports Luminaries Andre Agassi, Jerry Rice, Scottie Pippen, Helio Castrovenes, Richard 'Goose' Gossage Among Those Named 2008 'Great Sports Legends' 3Health News:Medicexchange.com Launches a New Dedicated Nuclear Medicine and Molecular Imaging Community for Medical Imaging Professionals 2Health News:New, Informative EAU Website Launched: http://www.urologyweek.org 2Health News:Second national scorecard on US health care system finds no overall improvement 2Health News:Second national scorecard on US health care system finds no overall improvement 3Health News:Second national scorecard on US health care system finds no overall improvement 4Health News:Second national scorecard on US health care system finds no overall improvement 5Health News:Vertos Medical Inc. Completes Series C Financing 2Health News:Vertos Medical Inc. Completes Series C Financing 3Health News:Vertos Medical Inc. Completes Series C Financing 4
(Date:12/17/2014)... KENNESAW, Ga. and RALEIGH, ... Clinical Trial Marketing Communications, LLC (CTMC), and Integrated ... in patient recruitment and retention for clinical trials ... called Integrated Clinical Trial Marketing Services (i-CTMS). i-CTMS ... and retention services to pharmaceutical, biotechnology and medical ...
(Date:12/15/2014)... DUBLIN , Dec. 12, 2014 Research ... announced the addition of the "MEMS Gyroscopes ... Costing Analysis" report to their offering. ... MEMS gyroscopes for tactical grade applications made a ... in term of reliability. They are now accepted ...
(Date:12/15/2014)... DUBLIN , Dec. 12, 2014 Research and ... ( http://www.researchandmarkets.com/research/ms3j8c/cardiac ) has announced the ... Estimates and Forecasts, 2012-2018"  report to their offering. ... by 2016. The North America ... while Europe claims approximately 25% ...
Breaking Medicine Technology:Integrated Clinical Trial Services and Clinical Trial Marketing Communications Form Joint Venture 2Integrated Clinical Trial Services and Clinical Trial Marketing Communications Form Joint Venture 3MEMS Gyroscopes Analog Devices ADIS16136 Precision Angular Rate Sensor Reverse Costing Analysis 2Cardiac Guidewires - Global Trends, Estimates and Forecasts, 2012-2018 2Cardiac Guidewires - Global Trends, Estimates and Forecasts, 2012-2018 3Cardiac Guidewires - Global Trends, Estimates and Forecasts, 2012-2018 4
... & Korsinsky is investigating the Board of Directors of ... GPRO ) for possible breaches of fiduciary duty and ... sale of the Company to Hologic, Inc. (Nasdaq: HOLX).  ... receive $82.75 for each share of Gen-Probe stock they ...
... Ventures, Inc. (OTCBB: SNPK) (the "Company" or "Sunpeaks Ventures") ... Circuit Court for Montgomery County, Maryland against Deal Flow Media, ... alleging that they engaged in a systematic series of false, ... in an attempt to cause harm to the Company. ...
Cached Medicine Technology:The Law Firm of Levi & Korsinsky, LLP Announces Investigation into Possible Breaches of Fiduciary Duty by the Board of Gen-Probe Incorporated in Connection with the Sale of the Company to Hologic, Inc. 2Sunpeaks Ventures Files Defamation Lawsuit 2
The ExcaliburPlus PC is the most powerful isolated ESU with 10,000 V PTP in spray coag....
The ExcaliburPlus PC is the most powerful isolated ESU with 10,000 V PTP in spray coag....
The CE marked HF coagulator which meets the highest ISO safety features....
Finesse II electrosurgical generator (100-120 VAC) utilizes a patented design that integrates the electrosurgical generator and smoke evacuation system into a single compact unit....
Medicine Products: