Navigation Links
Third generation Small pox vaccine from Cell-culture

Richard Greenberg and colleagues compared their Cell culture small pox vaccine// (CCSV) derived from cell culture with calf lymph derived vaccine. Small pox vaccine currently used is a live, attenuated vaccine virus derived from calf lymph. This vaccine produces adverse effects in vaccinated, 15-42 develop serious or life threatening adverse reactions of every million. 1 to 2 people every million die because of this vaccine. Serious side include eczema vaccinatum, progressive vaccinia, post vaccinal encephalitis, fetal vaccine, vaccina keratitis, myopericarditis.

Small pox vaccine is contraindicated in up to 30% or more population, including infants, pregnant women, immunocompromised, eczema patients, and cardiovascular conditions.

In this trial, the safety and immunogenecity, adverse effects were determined by neutralization, Antibody titers, T-cell proliferative response assays and interferon-? elispot. Only one vaccinated person developed pock lesions. The number of participants who became immune to the virus was high, with increased measures of cell mediated immunity in CCSV recipients. These results show CCSV vaccine is equally immunogenic and safe compared to calf lymph derived vaccine.

This new vaccine can solve the problem of calf lymph vaccine, as these existing stocks of calf lymph vaccine are mot than 20 years old, contamination by bovine prions can be avoided, unwanted immune response to bovine and other non-vaccina entities in vaccine.

Though, CCSV has advantages, we should be able to provide universal pre-exposure immunity to small pox. A safe, immunogenic, effective vaccine will provide a barrier against attempts to use small pox as a biological weapon. Research leading to the third generation vaccines, such as vaccinia viruses that are further attenuated, inactivated viruses, subunit or peptide based vaccines should have significant use to public health.


'"/>




Page: 1

Related medicine news :

1. Third artificial heart patient introduced
2. Surgery Offers Better Treatment For Third Degree Piles
3. One Third Of All Cancers Preventable!
4. Britain Announces Third Transfusion Related Mad Cow Case
5. Kleins Third Way Has Tough Opposition
6. Ignorance about AIDS rampart in Third of College Students: Chinese survey
7. Jalgaon: Third Phase Of Culling Operations Begin
8. Pramod Mahajan Undergoes Third Surgery
9. Third Arm Removed Successfully
10. Erection Drug Was Not Useful to Two-Thirds of Its Users
11. Babies Could Be exposed to Third Hand Smoke If Parents Are Smokers
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:5/31/2016)... ... May 31, 2016 , ... ... firm and statement solutions provider, for the tenth consecutive year as a ... issue of Advertising Age, and SourceLink ranked eighteenth in the “U.S. CRM/Direct Marketing ...
(Date:5/31/2016)... ... May 31, 2016 , ... CURE ... patients with cancer, has added Cancer and Careers to its ... timely content on continuing successful careers while fighting cancer. , As partners, both ...
(Date:5/30/2016)... ... ... As the CDC relaxes its stance on traditional No-Nit policies, parents wonder what ... free. , According to a May 26 article from news source KHON2 ... despite the fact that they may be harboring an infestation. Previous No-Nit policies stated ...
(Date:5/30/2016)... ... May 30, 2016 , ... Zane Benefits, the leader ... an original infographic, " Health Benefits Reimbursement Compliance Timeline ." , The ... complies with various federal regulations and reforms. , Navigating the new health reforms ...
(Date:5/30/2016)... ... May 30, 2016 , ... Another ER facility operated ... Plano, located at 3960 Legacy Drive, Plano, TX and is open 24 hours daily. ... Commerce followed by a medical open house. The Jasper High School band entertained attendees ...
Breaking Medicine News(10 mins):
(Date:5/30/2016)... , May 30, 2016 ... reach USD 7.3 billion by 2024, according to ... The increasing natality rate, the growing malnutrition coupled ... cancer and gastro-intestinal tract diseases are expected to ...      (Logo: http://photos.prnewswire.com/prnh/20150105/723757 ) , ...
(Date:5/30/2016)... LifeScienceIndustryResearch.com adds "Ulcerative Colitis ... with comprehensive information on the therapeutic development for ... stages, therapeutics assessment by drug target, mechanism of ... type, along with latest updates, and featured news ... involved in the therapeutic development for Ulcerative Colitis ...
(Date:5/27/2016)... LabStyle Innovations Corp . ( ... today announced that the Company,s Chief Financial Officer, Zvi ... held June 1-2 in New York, NY ... in Los Angeles, CA. ... operational milestones, including the U.S. FDA Clearance and commercial launch ...
Breaking Medicine Technology: