Navigation Links
Theory of How HIV Attacks is Wrong: Study

A popular theory on how HIV attacks the body's immune system is wrong, a new study has found.

Scientists have long believed that HIV causes the slow depletion of healthy white blood cells -- the T cells which recognize infections so the body can fight them off -- by causing infected T cells to produce virus particles before dying.

This ongoing cycle of infection, HIV production, reinfection and cell destruction has been called the "runaway" hypothesis.

But if this were so, the T cells would be killed off far too quickly, the researchers found.

Using a simple mathematical model, researchers in the United States and Britain showed the "runaway" model would deplete the body's healthy T cells in a matter of months, instead of the years it actually takes.

The results show that a "slow process must be active" in the depletion of the T cells, the authors wrote in the current issue of the journal PLoS Medicine.

Identifying this process "will provide a key insight into the nature of HIV disease and indicate potential new approaches to therapy," they concluded.

A potential explanation for the slow process could be that the virus slowly adapts over the course of the infection, the authors said.

"The virus is constantly mutating and there may be selection - in a Darwinian sense -- over time for 'fitter' mutants of the virus in an infected person," said lead author Andrew Yates of Emory University in Atlanta, Georgia.

"There are several ways the virus could become fitter - for example by being able to infect new cells more readily, or by infected cells producing more new virus, or producing it more rapidly," he said in an e-mail interview.

"The virus adaptation hypothesis requires a lot more experimental investigation, however, and is only a tentative conclusion."


'"/>




Page: 1

Related medicine news :

1. New Information On Virus Goes Against The Age-Old Theory
2. Controversial Theory Says DNA Can Be Pushed To "Dark States"
3. Study Refutes Theory on HIVs Effect on White Blood Cells
4. Maths Theory Shows Genetic Pattern of Tumour Growth
5. Heart Attacks during Menstruation!
6. Supply of Radiopharmaceuticals Hampered by Attacks
7. Air Pollution and Heart Attacks
8. Kidney Patients Risk Heart Attacks
9. Kidney Patients Risk Heart Attacks
10. New Medication May Decrease The Frequency Of Angina Attacks
11. Obese Kids Also Prone To Heart Attacks
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:8/18/2017)... ... August 18, 2017 , ... As an industry leader, Eppendorf ... they will present the line of epMotion automated liquid handling system. This automated ... automate everyday pipetting tasks. , Ideal for scientists and lab technicians with no ...
(Date:8/18/2017)... ... August 18, 2017 , ... Radabaugh ... protection assistance to communities in North-Central West Virginia, is embarking on a cooperative ... boys in the area. , The Chestnut Mountain Ranch (CMR) is a Christ-centered ...
(Date:8/18/2017)... IN (PRWEB) , ... August 18, 2017 , ... The ... communities in northwest Indiana, is campaigning in support of Campagna Academy in a charity ... to as the “Hoosier Boys’ Town of Indiana,” Campagna Academy is a nonprofit organization ...
(Date:8/18/2017)... ... August 18, 2017 , ... “Emotions are sacred, valid, honored, encouraged. This ... positive education company Generation Mindful. To help change the mindset of parents and educators ... skills, she created the Time-In Toolkit, which launched on Kickstarter 3 weeks ago and ...
(Date:8/18/2017)... ... August 18, 2017 , ... Alcovit, a lime-flavored beverage that rids the ... efforts with its product now available through Jet.com. , After 25 years of ... powdered drink is designed to quickly detox the body thereby avoiding alcohol-induced hangovers. Whether ...
Breaking Medicine News(10 mins):
(Date:8/8/2017)... Second-quarter 2017 revenues of $876 ... from continuing operations Second-quarter ... $110 million Second-quarter 2017 ... Second-quarter 2017 adjusted diluted ... percent to $0.93 Second-quarter ...
(Date:8/7/2017)...  Endo International plc (NASDAQ: ENDP ) ... all known U.S. mesh product liability claims and that ... remaining U.S. claims at reasonable values. Under the agreements, ... quarter of 2017 and continuing through the fourth quarter ... results, the Company intends to increase its mesh product ...
(Date:8/2/2017)... and BENTON, Ky. , Aug. 2, 2017   Marshall County ... its environmental services (ES) team to proactively reduce the risk of hospital-acquired infections (HAIs). The ... disinfection robot that uses UVC light energy to kill deadly pathogens such as C. ... Tru-D SmartUVC ... Tru-D in action in ...
Breaking Medicine Technology: