Navigation Links
The Polymicrobial Nature Of Diabetic Foot Infections

Foot infections are a major cause for hospitalization of patients with diabetes. Foot ulceration and infection are risks for subsequent amputation. Ischemia, neuropathy, and infection in patients with diabetes combine to produce tissue necrosis and ulcers//. Diabetic foot infections are generally polymicrobial in nature.

Early recognition of lesions and prompt initiation of appropriate antibiotic therapy, as well as aggressive surgical debridement of necrotic soft tissue and bone, and a modification of host factors (i.e., hyperglycemia, concomitant arterial insufficiency) are important for successful outcome.

A recent study, published in the May-June issue of Journal of Diabetes and its Complications, evaluated the bacteriology of diabetic foot ulcers at the Adan teaching hospital, Ministry of Health in Kuwait, Kuwait. The relative frequency of bacterial isolates cultured from community-acquired foot infections that were not exposed to antimicrobial agents for 30 days were studied. In addition, the bacterial comparative in vitro susceptibility to the commonly used antibacterial agents was assessed.

During the study, the infected wounds of 86 consecutive diabetic patients were cultured. The patients did not receive antimicrobial therapy 30 days prior to taking the cultures. The specimen was cultured using aerobic and anaerobic microbiological techniques. Isolates were tested for susceptibility to commonly used antimicrobial therapy. S. aureus and P. aeruginosa were found to be the most common causes of diabetic foot infections.

Anaerobic organisms, majority of them were bacteroids, are still a common cause for infection, although the prevalence is less. These wounds may require use of combined antimicrobial therapy for initial management. Among the gram-negative enteric bacilli, P. mirabilis was the most frequently seen, followed by Escherichia coli and Klebseilla. Imipenem, meropenem, and cefepime were th e most effective agents against gram-negative organisms. Vancomycin was the most effective against gram-positive organisms.

The authors suggest that while choosing an antimicrobial for the treatment of diabetic foot infections, one should consider the spectrum of causative organisms, their resistant patterns, efficacy, and safety. Awareness of the causative organisms in diabetic foot infections and their antimicrobial susceptibility pattern is essential for the institution of antimicrobial therapy.
'"/>




Related medicine news :

1. Reaction To ADHD Medication May Be Genetic By Nature
2. Risk Of Stroke May Be Genetic By Nature
3. Nature Cures The Best, Say WIC Clinic Clients
4. Nature’s fury leaves permanent scar
5. Nature’s Bounty ,Seaweed, Becomes A Blessing For Diabetes Patient
6. Morning Sickness - Natures Way Of Ensuring Healthy Diet In Pregnancy
7. Morning Sickness: Natures Warning Signal To Would –Be- Mom
8. Where Burnt Out Executives De-stress in Natures Lap
9. Nature Behind Most New Drugs
10. New Drug in Diabetic Neuropathy
11. Cinnamon May Help Diabetics
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:12/2/2016)... (PRWEB) , ... December 02, 2016 , ... For over twenty-four years, Doctors on ... to help personal injury victims find high quality medical care. When the company started ... area. Fast forward to present day and the now ten-page directory features a vast ...
(Date:12/2/2016)... Raleigh, NC (PRWEB) , ... December 02, 2016 , ... ... the Open Enrollment Period (or Annual Election Period), is ending December 7th. Currently-enrolled Medicare ... plan (Part C) or prescription drug plan (Part D) need to make changes during ...
(Date:12/2/2016)... (PRWEB) , ... December 02, 2016 , ... More than ... and while 84 percent of parents report speaking with their child about sex related ... sexually transmitted diseases. , Mediaplanet is proud to announce the launch of its second ...
(Date:12/2/2016)... ... December 02, 2016 , ... Sourced from the Isbre Springs beneath the ... its unmatched natural purity of just 6 ppm TDS (Total Dissolved Solids) in addition ... has been available in several ShopRite and FoodTown stores in NJ and received rave ...
(Date:12/2/2016)... ... 02, 2016 , ... On November 24th, 2016, Thanksgiving morning, ... different sites throughout Miami-Dade and Broward counties. This is the largest meal delivery ... Thanksgiving morning by putting together individual meals via assembly lines and passing them ...
Breaking Medicine News(10 mins):
(Date:12/2/2016)... , Dec 1, 2016 Research ... "Drug Delivery in Cancer - Technologies, Markets and Companies" ... , ... challenge in management of cancer The market value of ... Cancer market estimates from 2015-2025 are given according to organs involved ...
(Date:12/2/2016)... 2016 Around the corners of world, cancer ... habitable land present over earth. Cancer has become one ... a life time this is because of the increasing ... Given the steady increase in global cancer incidence with ... healthcare costs of treatment, there is increasing interest in ...
(Date:12/2/2016)... Dec. 2, 2016 Allergan plc (NYSE: ... information on its previously announced Accelerated Share Repurchase (ASR) Program. ... ... As previously announced, the Company entered into a ... the Company will repurchase $10 billion of its ordinary shares. ...
Breaking Medicine Technology: