Navigation Links
The Polymicrobial Nature Of Diabetic Foot Infections

Foot infections are a major cause for hospitalization of patients with diabetes. Foot ulceration and infection are risks for subsequent amputation. Ischemia, neuropathy, and infection in patients with diabetes combine to produce tissue necrosis and ulcers//. Diabetic foot infections are generally polymicrobial in nature.

Early recognition of lesions and prompt initiation of appropriate antibiotic therapy, as well as aggressive surgical debridement of necrotic soft tissue and bone, and a modification of host factors (i.e., hyperglycemia, concomitant arterial insufficiency) are important for successful outcome.

A recent study, published in the May-June issue of Journal of Diabetes and its Complications, evaluated the bacteriology of diabetic foot ulcers at the Adan teaching hospital, Ministry of Health in Kuwait, Kuwait. The relative frequency of bacterial isolates cultured from community-acquired foot infections that were not exposed to antimicrobial agents for 30 days were studied. In addition, the bacterial comparative in vitro susceptibility to the commonly used antibacterial agents was assessed.

During the study, the infected wounds of 86 consecutive diabetic patients were cultured. The patients did not receive antimicrobial therapy 30 days prior to taking the cultures. The specimen was cultured using aerobic and anaerobic microbiological techniques. Isolates were tested for susceptibility to commonly used antimicrobial therapy. S. aureus and P. aeruginosa were found to be the most common causes of diabetic foot infections.

Anaerobic organisms, majority of them were bacteroids, are still a common cause for infection, although the prevalence is less. These wounds may require use of combined antimicrobial therapy for initial management. Among the gram-negative enteric bacilli, P. mirabilis was the most frequently seen, followed by Escherichia coli and Klebseilla. Imipenem, meropenem, and cefepime were th e most effective agents against gram-negative organisms. Vancomycin was the most effective against gram-positive organisms.

The authors suggest that while choosing an antimicrobial for the treatment of diabetic foot infections, one should consider the spectrum of causative organisms, their resistant patterns, efficacy, and safety. Awareness of the causative organisms in diabetic foot infections and their antimicrobial susceptibility pattern is essential for the institution of antimicrobial therapy.
'"/>




Related medicine news :

1. Reaction To ADHD Medication May Be Genetic By Nature
2. Risk Of Stroke May Be Genetic By Nature
3. Nature Cures The Best, Say WIC Clinic Clients
4. Nature’s fury leaves permanent scar
5. Nature’s Bounty ,Seaweed, Becomes A Blessing For Diabetes Patient
6. Morning Sickness - Natures Way Of Ensuring Healthy Diet In Pregnancy
7. Morning Sickness: Natures Warning Signal To Would –Be- Mom
8. Where Burnt Out Executives De-stress in Natures Lap
9. Nature Behind Most New Drugs
10. New Drug in Diabetic Neuropathy
11. Cinnamon May Help Diabetics
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:1/17/2017)... ... January 17, 2017 , ... Kevin Harrington (one of the original Sharks ... DRTV campaigns regarding the topic of Beauty and Personal Care. , ... What better way to commit to these changes than beginning with personal care and ...
(Date:1/17/2017)... Florida (PRWEB) , ... January 17, 2017 , ... ... City, a new 21st century approach to infusing high speed technology into the ... area exclusively dedicated to the advancement of healthcare and wellness in a yet-to-be-named, ...
(Date:1/17/2017)... ... ... Mirror Mirror Beauty Boutique, Houston’s premiere CoolSculpting provider , is proud ... Rewards Program. Practice founder, Paul Vitenas, MD FACS, is delighted that Mirror Mirror Beauty ... by Zeltiq, CoolSculpting is approved by the Food and Drug Administration as a safe ...
(Date:1/17/2017)... ... January 17, 2017 , ... Peoples ... the Peoples Health network on Dec. 1, 2016. Peoples Health, a Metairie-based Medicare ... Center is an exciting addition to our provider network, and the addition will ...
(Date:1/17/2017)... ... , ... A prescription medication bottle, pocket knife, luggage and a solar-powered aluminum ... Design Challenge , the Cradle to Cradle Products Innovation Institute has announced. ... to run through early 2018. The challenges are presented by the Institute in partnership ...
Breaking Medicine News(10 mins):
(Date:1/17/2017)... -- EU5 Glucose Monitoring Market Outlook to 2022 ... Market Outlook to 2022", provides key market data on ... in millions of US dollars, volume (in units) and ... Meters, Blood Glucose Test Strips and Lancets. The ... for each of these market segements, and global corporate-level ...
(Date:1/17/2017)... Jan. 17, 2017 Paragon Bioservices received a ... development services for a variety of National ... medical product development activities. The IDIQ mechanism will ... for task order awards up to $159 million. ... manufacturing and process development of biopharmaceuticals, is one ...
(Date:1/17/2017)... HARRISBURG, Pa. , Jan. 17, 2017 /PRNewswire-USNewswire/ ... today announced applications for medical marijuana growers/processors ... Medical Marijuana Program website . Permit applications ... 20, 2017. "This is an important ... patients who desperately need it," Secretary Murphy said. ...
Breaking Medicine Technology: