Navigation Links
The Pain from Fibromyalgia Is Real, Researchers Say

Many people with fibromyalgia – a debilitating pain syndrome that affects 2 to 4 percent of the population – have faced the question of whether the condition is real.//

Fibromyalgia often has been misdiagnosed as arthritis or even a psychological issue. Increasingly, though, the scientific knowledge about fibromyalgia is growing, and a new paper from the University of Michigan Health System says there are “overwhelming data” that the condition is real, is characterized by a lower pain threshold and is associated with genetic factors that can make some people more likely to develop fibromyalgia.

The review paper, in the December issue of the journal Current Pain and Headache Reports, cites recent studies involving pain, genetics, brain activity and more. The paper's authors hope these findings will lead to a better understanding and acceptance of fibromyalgia and related conditions.

“It is time for us to move past the rhetoric about whether these conditions are real, and take these patients seriously as we endeavor to learn more about the causes and most effective treatments for these disorders,” says Richard E. Harris, Ph.D., research investigator in the Division of Rheumatology at the U-M Medical School's Department of Internal Medicine and a researcher at the U-M Health System's Chronic Pain and Fatigue Research Center.

A growing amount of research related to the neurobiology of this condition supports the notion that the pain of fibromyalgia is real. Studies at U-M and elsewhere using two neuroimaging techniques – functional magnetic resonance imaging (fMRI) and single photon emission computed tomography (SPECT) – indicate there is a difference between patients with and without fibromyalgia.

“In people without pain, these structures encode pain sensations normally. In people with fibromyalgia, the neural activity increased,” says Daniel J. Clauw, M.D., director of the U-M Chronic Pain and Fatigue Research Center and professor of rheumatology at the U-M Medical School, and an author of the new paper. “These studies indicate that fibromyalgia patients have abnormalities within their central brain structures.”

In a 2003 paper in the journal Science, a U-M team reported that a small variation in the gene that encodes the enzyme called catechol-O-methyl transferase, or COMT, made a significant difference in the pain tolerance, and pain-related emotions and feelings, of healthy volunteers. Researchers also have found that individual mutations in the COMT gene are related to the future development of temporomandibular joint disorder, also known as TMD or TMJ, a condition related to fibromyalgia.

Together, these studies about COMT and numerous studies with animals suggest that pain sensitivity is determined at least in part by a person’s genetic makeup, Clauw says.

Source-Newwise
SRM
'"/>




Related medicine news :

1. Relief For Women Suffering From Fibromyalgia
2. Fibromyalgia Patients May Be Soothed By Acupuncture
3. Acupuncture to Relieve Fibromyalgia Symptoms
4. Acupuncture Links Positively With Fibromyalgia Cure
5. Fibromyalgia Increases Pain and Fatigue for Pregnant Women
6. Pregabalin Proves Durable Pain Relief Option for Fibromyalgia
7. Researchers urge caution in using ear tube surgery
8. Researchers Scale to assess the Severity of Epilepsy in Kids
9. Researchers trick Alzheimers Enzyme
10. Researchers find new HIV hiding place
11. New Hair in 15 Days Could Now Be A Possibility Say Researchers
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:2/23/2017)... ... February 23, 2017 , ... CALNOC, the nation’s first and only ... their upcoming conference – Empowerment, Value and Collaboration – in Seattle, WA on October ... the Virginia Mason Health System in Seattle since 2000. In addition to his role ...
(Date:2/23/2017)... CHURCH, Va. (PRWEB) , ... February 23, 2017 , ... ... worries, or problems. He has also continued to spiritually evolve, which is the purpose ... published book “ Our Spiritual Truths ” (published by Balboa Press) attempts to guide ...
(Date:2/22/2017)... ... February 22, 2017 , ... The Waismann Method® ... of individuals who have recently fallen victim to America’s opioid epidemic. Now, opiate dependent ... California, where they are free from the shame, stigma, and harmful labeling ...
(Date:2/22/2017)... ... February 22, 2017 , ... ... accurately understand each Medicare Advantage member’s risk, identify any gaps-in-coding, as well ... solution helps transform the HCC Risk Adjustment process from a typical fragmented ...
(Date:2/22/2017)... ... February 22, 2017 , ... THR ... “NANOCALM 300” Microemulsified Hemp Extract. This premier nanoemulsified CBD product utilizes Quicksilver ... the bloodstream. Far outpacing the absorption speed of all other products, ...
Breaking Medicine News(10 mins):
(Date:2/23/2017)... NEW YORK , Feb. 22, 2017 This ... US$ Thousand. The report provides separate comprehensive analytics for the ... , Europe , Asia-Pacific ... World. Annual estimates and forecasts are provided for the period ... for these markets. Market data and analytics are derived from ...
(Date:2/23/2017)... England and DEERFIELD, Ill. ... U.S.A. , Inc., a wholly-owned subsidiary of ... a joint venture between Cambridge Cognition Holdings PLC and ... use of a specially designed app on an Apple ... patients with Major Depressive Disorder (MDD). Depression ...
(Date:2/23/2017)... , Feb. 23, 2017  CTI BioPharma Corp. ... management plans to report its fourth quarter and full ... the close of the U.S. financial markets. Following the ... webcast conference call to discuss the results and provide ... Access to the event can be obtained as follows: ...
Breaking Medicine Technology: