Navigation Links
The Link Between Rheumatoid Arthritis and Cancer

Patients with rheumatoid arthritis (RA), a chronic inflammatory autoimmune disease, have a high risk of death from disease – at least double// the risk of the general population, studies overwhelmingly show. Evidence has been less clear on whether RA patients are exceptionally vulnerable to dying from cancer.

The first study to investigate whether patients with RA who develop cancer have a decreased rate of survival, featured in the issue of Arthritis & Rheumatism, also examined the impact of rheumatic disease on overall cancer incidence. Conducted by a team of researchers in the United Kingdom, it focused on 2,105 patients with recent onset inflammatory polyarthritis (IP). Over time, a large proportion of new-onset IP cases evolve into RA, meeting the diagnostic criteria of the American College of Rheumatology.

Researchers followed the IP patients over a 10-year period to detect the occurrence of cancer. Among the group, they identified 123 cases of cancer for analysis. These cases included bone, lung, breast, prostate, urinary, colon, and brain cancers; cancers of the digestive, respiratory, and central nervous systems; cancers of the blood cells and cancerous tumors; but excluding non-melanotic skin cancers. Then, they compared these rates with the rates of cancer in the general population from the same geographic area, Norfolk, adjusting for difference in age and sex. Overall, the incidence of cancer was not increased in the IP subjects compared with the general population. However, the risk of blood cell cancers was increased among the IP sample, a finding researchers expected given the association between RA and lymphoma.

The study also compared the number of deaths in patients with cancer and inflammatory arthritis with that of cancer patients without a history of inflammatory arthritis. The finding was striking: a 40 percent increase in mortality in patients who suffered both IP, or RA, and cancer.

"The resul ts of this study demonstrated that 5-year cancer survival in patients with IP is substantially reduced in comparison with that in the general population, even after adjusting for differences in age, sex, and cancer site, whereas the overall cancer incidence does not seem to be increased," observes Alan Silman, M.D., an epidemiologist with the University of Manchester and the study’s leading researcher. Whether targeted cancer therapies could improve the survival rate for RA patients remains a subject for further research.

Source-Eurekalert
SR
'"/>




Related medicine news :

1. Link Between Infection And Heart Disease
2. Prescription Drug Use Varies Widely Between States
3. Wait Between Pregnancies
4. Link Between Migraines and Behavioral Disorders
5. Link Between Obesity and Behavior in Kids
6. Link Between Mothers Depression and Violence in Children
7. Link Between Alcohol and Decrease in Brain Size
8. Link Between Musculoskeletal Pain and Vitamin D Deficiency
9. Link Between Hyperglycemia & Hospital Mortality
10. Link Between Alcohol Consumption And Cardiovascular Disease
11. Understanding The Link Between Hormone Replacement and Respiratory Disease
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/25/2016)... ... June 25, 2016 , ... The temporary closing of Bruton Memorial Library on June ... , brings up a new, often overlooked aspect of head lice: the parasite’s ability to ... is not a common occurrence, but a necessary one in the event that lice have ...
(Date:6/25/2016)... ... 2016 , ... On Friday, June 10, Van Mitchell, Secretary of the Maryland ... iHire in recognition of their exemplary accomplishments in worksite health promotion. , The Wellness ... & Wellness Symposium at the BWI Marriott in Linthicum Heights. iHire was one of ...
(Date:6/24/2016)... (PRWEB) , ... June 24, 2016 , ... Marcy was in a crisis. Her son ... lash out at his family verbally and physically. , “When something upset him, he couldn’t ... would use it. He would throw rocks at my other children and say he was ...
(Date:6/24/2016)... ... ... of Topricin and MyPainAway Pain Relief Products, join The ‘Business for a Fair Minimum Wage’ ... 2020 and then adjusting it yearly to increase at the same rate as the median ... floor does not erode again, and make future increases more predictable. , The company is ...
(Date:6/24/2016)... Maryland (PRWEB) , ... June 24, 2016 , ... ... Angels is actively feeding the Frederick area economy by obtaining investment capital for ... over the past 2½ years that have already resulted in more than a ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... BEIJING , June 24, 2016 Dehaier ... or the "Company"), which develops, markets and sells medical ... China , signed a strategic cooperation agreement with ... as "Hongyuan Supply Chain") on June 20, 2016, to ... Under the strategic cooperation agreement, Dehaier will leverage Hongyuan ...
(Date:6/24/2016)... , Belgium , June 24, ... VNRX), today announced the appointment of Dr. ... Directors as a Non-Executive Director, effective June 23, ... Audit, Compensation and Nominations and Governance Committees.  As ... Futcher will provide independent expertise and strategic counsel ...
(Date:6/23/2016)... 2016 Research and Markets has ... by Type (Organic Chemical (Sugar, Petrochemical, Glycerin), Inorganic Chemical), ... Parenteral) - Global Forecast to 2021" report to ... The global pharmaceutical excipients market is projected to reach ... 6.1% in the forecast period 2016 to 2021. ...
Breaking Medicine Technology: