Navigation Links
The Exposure Of Cadmium And Its Effects On Kidneys

In 1999 an ongoing population-based Swedish study, Women's Health in the Lund Area, was expanded to include low-level cadmium exposure. Analysis of the data collected now reveals a small but significant kidney response to low-level cadmium exposure [EHP 113:1627-1631]//. This suggests that low-level cadmium exposure may pose a significant public health risk. The general population is likely to encounter low-level chronic exposure through smoking and from dietary sources, particularly shellfish, grains, and vegetables.

Owing to extremely slow excretion, cadmium accumulates in the body, especially in the kidneys. Kidney damage is the primary consequence, but most toxicity data are from exposures in occupational settings or severely polluted areas. The effects of low-level exposure are less certain.

The team analyzed data, including blood and urine samples, collected from 820 women aged 54-63 years. Blood levels of creatinine and cystatin C were measured in 742 participants to calculate glomerular function. Urinary concentrations of calcium, human complex-forming protein, and N-acetyl-a-D-glucosaminidase--all markers of tubule function--were available for 813 women. The researchers additionally collected data on medications taken, smoking history, lead exposure, and incidence of diabetes and hypertension to control for potential confounding factors.

Cadmium concentrations were similar or slightly higher compared with previous data from Sweden and much lower than concentrations reported for populations in highly polluted areas in Europe and Japan. Current or former smokers had cadmium concentrations that were 90% higher in blood and 40% higher in urine than concentrations measured in participants who never smoked. Consequently, multivariate analyses were conducted on data from all participants as one group and from those who had never smoked as another group.

The researchers speculate that effect levels might be even lower fo r people with diabetes, a disease carrying high risk of kidney damage similar to that caused by cadmium exposure. Although the effects of low-level cadmium exposure are clinically minor, they should be viewed as early indicators of potential severe health effects, according to the researchers. Given the size of the exposed population, there may be a significant public health risk, and efforts beyond smoking cessation programs are needed to reduce exposure.

Source: Environmental Health Perspectives
'"/>




Related medicine news :

1. Exposure to EMF may cause leukemia
2. Exposure To Tobacco Smoke Can Lead To Sickle Cell Crisis
3. Radiation Exposure Found To Affect Intellect Later In Life
4. Cancer Risk From Exposure To Diagnostic X-Rays
5. Limiting Infants Exposure To Smoke At Home
6. Exposure To Night Light may Increase The Risk Of Leukemia
7. Understanding The Harmful Effects Of Radiation Exposure
8. Asbestos Exposure Associated With An Increased Risk For Autoimmune Disease
9. Low dose Radiation Exposure May Cause Cancer
10. Exposure to cigarette smoke when in the womb can lead to asthma
11. Exposure to Pesticides in Schools Produces Illnesses Among Employees, Students
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:10/12/2017)... ... October 12, 2017 , ... HMP , a leader in healthcare events ... Magazine Eddie Digital Award for ‘Best B-to-B Healthcare Website.’ Winners were announced during the ... The annual award competition recognizes editorial and design excellence across a range of sectors. ...
(Date:10/12/2017)... ... October 12, 2017 , ... On Saturday, October 21, the Health & Wellness ... Moonlight to raise money for the American Heart Association Heart Walk. Teams of up ... work together to keep their treadmills moving for 5 hours. Treadmills will start at ...
(Date:10/12/2017)... (PRWEB) , ... October 12, 2017 , ... ... (HLA), the nation's first interactive health literacy software tool, and the Cancer Patient ... aspects of cancer patient education, today announce a new strategic alliance. , ...
(Date:10/12/2017)... ... October 12, 2017 , ... ... in wound care advancements to physician colleagues, skilled nursing facility medical directors and ... the Treacherous Waters of Wound Care." , "At many of these conferences we ...
(Date:10/12/2017)... , ... October 12, 2017 ... ... life sciences content management, presents its enhanced Pepper Flow promotional review platform ... -18, 2017. Pepper Flow’s increased insight-driven capabilities help marketers streamline the medical, ...
Breaking Medicine News(10 mins):
(Date:9/19/2017)... ANN ARBOR, Mich. , Sept. 19, 2017 HistoSonics, Inc., a venture-backed medical ... the precise destruction of targeted tissues, announced three leadership team developments today:   ... Josh Stopek, PhD ... ... Veteran medical device executive ...
(Date:9/18/2017)... KALAMAZOO, Mich. , Sept. 18, 2017 /PRNewswire/ ... and OptiMed Specialty Pharmacy of Kalamazoo, Mich. ... a strategic hub service that expedites and streamlines patient ... spirometer, Spiro PD 2.0, and wellness management services.  ... a medical device used to measure lung function for ...
(Date:9/13/2017)... 13, 2017   OrthoAtlanta has been named the ... Host Committee (AFHC) for the 2018 College Football Playoff (CFP) ... at Mercedes-Benz Stadium in Atlanta, Georgia . ... "I,m In" campaign, participating in many activities leading up to, ... ...
Breaking Medicine Technology: