Navigation Links
The Exposure Of Cadmium And Its Effects On Kidneys

In 1999 an ongoing population-based Swedish study, Women's Health in the Lund Area, was expanded to include low-level cadmium exposure. Analysis of the data collected now reveals a small but significant kidney response to low-level cadmium exposure [EHP 113:1627-1631]//. This suggests that low-level cadmium exposure may pose a significant public health risk. The general population is likely to encounter low-level chronic exposure through smoking and from dietary sources, particularly shellfish, grains, and vegetables.

Owing to extremely slow excretion, cadmium accumulates in the body, especially in the kidneys. Kidney damage is the primary consequence, but most toxicity data are from exposures in occupational settings or severely polluted areas. The effects of low-level exposure are less certain.

The team analyzed data, including blood and urine samples, collected from 820 women aged 54-63 years. Blood levels of creatinine and cystatin C were measured in 742 participants to calculate glomerular function. Urinary concentrations of calcium, human complex-forming protein, and N-acetyl-a-D-glucosaminidase--all markers of tubule function--were available for 813 women. The researchers additionally collected data on medications taken, smoking history, lead exposure, and incidence of diabetes and hypertension to control for potential confounding factors.

Cadmium concentrations were similar or slightly higher compared with previous data from Sweden and much lower than concentrations reported for populations in highly polluted areas in Europe and Japan. Current or former smokers had cadmium concentrations that were 90% higher in blood and 40% higher in urine than concentrations measured in participants who never smoked. Consequently, multivariate analyses were conducted on data from all participants as one group and from those who had never smoked as another group.

The researchers speculate that effect levels might be even lower fo r people with diabetes, a disease carrying high risk of kidney damage similar to that caused by cadmium exposure. Although the effects of low-level cadmium exposure are clinically minor, they should be viewed as early indicators of potential severe health effects, according to the researchers. Given the size of the exposed population, there may be a significant public health risk, and efforts beyond smoking cessation programs are needed to reduce exposure.

Source: Environmental Health Perspectives
'"/>




Related medicine news :

1. Exposure to EMF may cause leukemia
2. Exposure To Tobacco Smoke Can Lead To Sickle Cell Crisis
3. Radiation Exposure Found To Affect Intellect Later In Life
4. Cancer Risk From Exposure To Diagnostic X-Rays
5. Limiting Infants Exposure To Smoke At Home
6. Exposure To Night Light may Increase The Risk Of Leukemia
7. Understanding The Harmful Effects Of Radiation Exposure
8. Asbestos Exposure Associated With An Increased Risk For Autoimmune Disease
9. Low dose Radiation Exposure May Cause Cancer
10. Exposure to cigarette smoke when in the womb can lead to asthma
11. Exposure to Pesticides in Schools Produces Illnesses Among Employees, Students
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:12/8/2016)... ... 2016 , ... The Compretta Insurance Agency, a family owned insurance and financial ... Hancock County area, is announcing the launch of a charity effort aimed at raising ... Food Pantry has worked for more than 30 years to meet the food needs ...
(Date:12/7/2016)... ... December 07, 2016 , ... DrugDev again demonstrated its ... is one of the early adopters completing EU-U.S. Privacy Shield Certification from the U.S. ... companies on both sides of the Atlantic with a mechanism to comply with EU ...
(Date:12/7/2016)... Kenosha, Wisconsin (PRWEB) , ... December 07, 2016 , ... ... the extraordinary new MedMaster™ MPCNGX . The MPCNGX is a multi-function, sealed, LED ... the right amount of light where and when it’s needed. , A ...
(Date:12/7/2016)... ... December 07, 2016 , ... Wavelink, an industry ... Control through a new partnership with Splashtop Inc. This remote control for Android ... to help businesses maximize their uptime and productivity. , Wavelink offers powerful enterprise ...
(Date:12/7/2016)... ... December 07, 2016 , ... In the early morning of October 30, ... medical call when he lost control of his patrol car. The vehicle overturned into ... he was transported to Atlanta Medical Center, where he later succumbed to his injuries. ...
Breaking Medicine News(10 mins):
(Date:12/8/2016)... , Dec. 8, 2016  EIP Pharma, LLC ... obtained proof-of-mechanism for neflamapimod (previously code named VX-745), ... 2a clinical trials that demonstrated significant Alzheimer,s disease ... (12-week treatment) and Study 303 (6-week treatment) are ... in Alzheimer,s Disease (CTAD) scientific conference in ...
(Date:12/8/2016)... 2016 Dignitana, a world leader in medical ... Technology, creator of the award-winning, patented Boa® system, to ... the DigniCap® scalp cooling system. DigniCap® was cleared by ... and is the first medical scalp cooling device to ... system features a patented tight-fitting silicone cooling cap that ...
(Date:12/8/2016)... SAN DIEGO , Dec. 8, 2016 /PRNewswire/ ... dedicated to improving cancer patient care from diagnosis ... the company,s recently completed Phase 1b study in ... at the San Antonio Breast Cancer Symposium. ... Cancer Center at UC San Diego Health, delivered ...
Breaking Medicine Technology: