Navigation Links
The Adverse Effects Of Asthma Medication

Latest research shows that a common class of drugs used for acute asthma attacks might be causing the very thing it aims to treat.//

Researchers studied the use of bronchodilators known as beta-agonists in asthmatics.Beta-agonists are the primary treatment used to relieve acute asthma attacks. The drugs come in many forms -- they may be delivered with an inhaler, given in pill or liquid form, delivered in a nebulizer, or given by injection. Whatever the mode of administration, they work by relaxing the airway and reducing airway responsiveness to allergens that cause it to restrict and cause an acute attack. Many people with asthma rely heavily on these medications, sometimes taking them several times a day.

Previous research suggests regular use could increase sensitivity to airway constriction and thus lead to a greater number of attacks and more serious attacks, primarily by causing a desensitization of the beta2-adrenergic receptor (beta2AR) that the drug binds with to achieve its effects.

Based on the study researchers suggest an alternative mechanism. Their study finds the increased airway hyperresponsiveness seen in some regular users of beta-2 agonists may be due to increased expression of a substance called phospholipase C-beta (PLC-beta) in the smooth airway muscle that occurs with persistent high-level activation of the beta2AR. The finding may lead to new treatments for asthma targeting PLC-beta.

Thus researchers conclude saying that understanding the panoply of beta2AR-mediated events in airway smooth muscle might lead to the design of new agonists that avoid negative effects of beta2AR activation while enhancing events that lead to relaxation.
'"/>




Page: 1

Related medicine news :

1. Spanking can Cause Adverse Effects Later In Life
2. Adverse Effects Associated with Unauthorised Hepatitis A Vaccine in China
3. Liver Adversely Affected By A Diet High In Fat
4. Bisphenol A In Food Containers Has Adverse Effect On Brain Tissue
5. Obesity Has Adverse Impact On Breast Cancer Survival
6. New Immigration Rule Adversely Affects Indian Doctors
7. Stress At Job Adversely Affects Blood Pressure
8. ‘Adverse events’ eat into NZ health budgt
9. HIV/AIDS Epidemic to Cause Adverse Effects to Indian Economy
10. Antibiotic Drug Recalled Following Adverse Effects
11. Philippines Oil Spill Causing Adverse Health Effects
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/25/2016)... ... June 25, 2016 , ... The temporary closing of Bruton Memorial Library on June 21 due ... up a new, often overlooked aspect of head lice: the parasite’s ability to live away ... a common occurrence, but a necessary one in the event that lice have simply gotten ...
(Date:6/25/2016)... Oklahoma (PRWEB) , ... June 25, 2016 , ... ... both athletes and non-athletes recover from injury. Recently, he has implemented orthobiologic procedures ... Oklahoma City area —Johnson is one of the first doctors to perform the ...
(Date:6/24/2016)... ... 24, 2016 , ... Those who have experienced traumatic events may suffer from ... avenues, such as drug or alcohol abuse, as a coping mechanism. To avoid this ... coping following a traumatic event. , Trauma sufferers tend to feel a range of ...
(Date:6/24/2016)... ... 24, 2016 , ... Global law firm Greenberg Traurig, P.A. announced that 20 ... by their peers for this recognition are considered among the top 2 percent of ... honors as members of this year’s Legal Elite Hall of Fame: Miami Shareholders ...
(Date:6/24/2016)... , ... June 24, 2016 , ... People across the ... Genome magazine’s Code Talker Award, an essay contest in which patients and their families ... to be presented at the 2016 National Society of Genetic Counselors (NSGC) Annual Education ...
Breaking Medicine News(10 mins):
(Date:6/26/2016)... , June 27, 2016  VMS Rehab Systems, Inc. ... will take whatever measures required to build a strong ... which is currently listed on the OTC Markets-pink current ... Chairman and CEO, "We are seeing an anomaly in ... understand, not only by the Company, but shareholders and ...
(Date:6/24/2016)... June 24, 2016  Collagen Matrix, Inc., ("Collagen ... and manufacturing of collagen and mineral based medical ... that Bill Messer has joined the ... further leverage the growing portfolio of oral surgery, ... Bill joins the Collagen Matrix executive team ...
(Date:6/24/2016)... Dublin ... of the " Global Markets for Spectroscopy Equipment" ... This report focuses on the global ... including its applications in various applications. The report deals ... three main industries: pharmaceutical and biotechnology, food and beverage, ...
Breaking Medicine Technology: