Navigation Links
Testosterone Decline in Men Linked to Lifestyle, Increases in Obese Girls

The following highlights represent papers accepted for publication in the Journal of Clinical Endocrinology and Metabolism (JCE&M), as well as new patient information// provided by The Hormone Foundation, the public education affiliate of The Endocrine Society.

Lifestyle Accelerates Testosterone Decline

Testosterone concentrations in men normally decline with age, but a new study confirms that many health and lifestyle changes can significantly accelerate that decline. Research reveals that a Body Mass Index (BMI) increase of only 4-5 points had the same diminishing effect on total testosterone as approximately 10 years of aging. A similar decline in testosterone was also associated with a traumatic emotional event, such as the loss of a spouse. “Understanding this phenomenon is important because low levels of testosterone may contribute to such conditions as diabetes, reduced bone and muscle mass, impaired sexual function, and a generally decreased quality of life,” said Thomas G. Travison, PhD, lead author of the study.

The researchers analyzed data on 1,667 subjects enrolled in the Massachusetts Male Aging Study (MMAS), a longitudinal study of men’s health and endocrine functioning. The MMAS tracked subjects’ history of chronic illness, tobacco use, alcohol consumption, dietary intake, and physical activity.

This study provides compelling evidence that specific changes in health and lifestyle – such as an increase in BMI – are accompanied by an accelerated loss of serum testosterone. While these lifestyle changes cannot be proven to be the cause of associated testosterone declines, they appear at least as significant as – if not more than -- short to mid-term aging effects. These results suggest the possibility that age-related hormone decline could be minimized by managing health and lifestyle factors.

Obesity More than Doubles Testosterone in Pubertal Girls

Compared to thei r normal weight counterparts, obese girls have significantly higher levels of testosterone before and during puberty (i.e., the peripubertal phase). Researchers have found that mean concentrations of free serum testosterone in obese peripubertal girls were two-to-nine times higher than in normal weight peripubertal girls. This difference appeared to be especially prominent during the earlier pubertal stages. In addition to elevated testosterone concentrations, obese girls also had insulin concentrations that were up to three times higher than for normal weight girls. Increased insulin levels suggest insulin resistance, which also raises the specter of an increased risk of developing diabetes later in life.

For this study, researchers examined 30 normal weight girls and 74 obese girls, as measured by Body Mass Index (BMI) standardized for age, in various stages of puberty. The girls’ pubertal stage was categorized by Tanner breast staging, which is the standard physical exam measure used by pediatricians.

The early stages of puberty (Tanner 1-3) are particularly critical times in a girl’s development. “Since this is when the complex interactions governing the menstrual cycle are being established, excess testosterone during this time could impact the future reproductive health of women,” said Dr. Christopher R. McCartney, lead author of the study. “Though, the long-term implications of elevated testosterone during puberty have yet to be established.” McCartney also noted that high testosterone levels can promote excessive hair growth, though it could take a few years for these symptoms to materialize in subjects.

Source-Newwise
SRM
'"/>




Related medicine news :

1. Testosterone Replacement Therapy Safe If Monitored Appropriately
2. Low Testosterone Levels the Cause Of Depression In Men
3. The Use Of Testosterone Replacement Therapy Questioned
4. Depression In Men Could Be To Low Testosterone Levels
5. Testosterone patch for women Rejected For safety Reasons
6. Testosterone Patches Found To Increase Sexual Desire In Menopausal Women
7. Testosterone Therapy can improve sexual function in postmenopausal women
8. Fatherhood Found To Tame Men by Reducing Testosterone Levels
9. Testosterone levels could serve as a marker for determining risk of SIDS
10. Males Lifespan Shortened By Elevated Levels Of Testosterone
11. Study Indicates An Increased Risk Of Breast Cancer In Women Undertaking Estrogen and Testosterone Therapy
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:5/2/2016)... ... ... The 2016 World Ultimate & Guts Championship (WUGC) Mixed roster was announced in February and ... WUGC is being held in London, England this year from June 18-25. At the last ... gold in the women’s masters division, and a silver in the women’s division, so Mazur ...
(Date:5/2/2016)... ... May 02, 2016 , ... ... will be held at the Bellagio Hotel in Las Vegas, NV from October ... (NASW) will be co-hosting the event. , This year’s conference will offer ...
(Date:5/2/2016)... , ... May 02, 2016 , ... Dr. Jonathan Kulbersh of Carolina Facial Plastics isn’t ... number five on the list of “ 5 US Cities with the Highest Plastic Rates ... Angeles, and Miami. The results were calculated using a survey by RealSelf ...
(Date:5/2/2016)... Ocean City, MD (PRWEB) , ... May 02, 2016 , ... ... high quality SUP boards at affordable prices announced today the outcome of their partnership ... what has been termed the “Roots Yoga Board.” , SUP yoga has seen a ...
(Date:5/2/2016)... ... May 02, 2016 , ... In response to recent growth and ... Low Vision and Blindness (NELV&B) , announces the opening of a new low vision ... with vision impairments to get assessments, hands-on experience and training with low vision and ...
Breaking Medicine News(10 mins):
(Date:4/28/2016)... , April 28, 2016 ... George Phillips und Stephen ...    ArisGlobal®, ein führender Anbieter ... gab heute bekannt, dass neue Führungskräfte zum ... gestoßen sind, die vielfältige Erfahrungen mitbringen.  Dies ...
(Date:4/28/2016)... April 28, 2016 Oramed Pharmaceuticals Inc. ... pharmaceutical company focused on the development of oral drug delivery ... upcoming PIONEERS 2016 conference, presented by Joseph Gunnar ... New York . Nadav Kidron , ... conference. Presentation Details:   PIONEERS ...
(Date:4/27/2016)... 27, 2016  Hologic, Inc. (Nasdaq: ... for the fiscal second quarter ended March 26, ... $0.24 increased 41.2%, and non-GAAP diluted EPS of ... 5.8% on a reported basis, and 6.3% on ... posted another good quarter, highlighted by 14.6% growth ...
Breaking Medicine Technology: