Navigation Links
Test for Esophageal Reflux Licensed to Bayer by University

A new test for esophageal reflux disease developed by a Wake Forest University Health Sciences (WFUHS) otolaryngologist has been licensed to Bayer HealthCare’s Diagnostics Division by WFUHS.//

The test, which detects the presence of human pepsin 3b in a patient’s saliva, was developed by Jamie Koufman, M.D., then professor of otolaryngology at Wake Forest University School of Medicine and director of WFUHS’s Center for Voice Disorders. She is now director of the Voice Institute of New York.

The test potentially could be used in the offices of primary care physicians and avoid the need for more elaborate and expensive tests. Bayer will market the test.

“Most people associate heartburn with excess stomach acid, but it is the digestive enzyme pepsin (and not acid) bathing the lower area of the esophagus that causes the damage,” said Koufman. “For patients with severe esophagitis, the tissue in the esophagus is literally being self-digested.”

“Besides helping to diagnose gastroesophageal reflux disease, or ‘GERD,’ detecting pepsin in saliva also should help diagnose laryngopharyngeal reflux disease, the backflow of stomach contents into the throat,” she said. “Laryngopharyngeal reflux disease is even more difficult to diagnose than GERD. Scientific evidence points to aerosolized pepsin being drawn into the respiratory system as a common culprit of chronic cough, asthma, and even sinusitis.”

Dean Stell, associate director of the Office of Technology Asset Management, said, “Bayer is a world leader in point-of-care diagnostics and is well qualified to handle the next stage of development. That is the essence of technology transfer – working with our industrial counterparts who can develop technology in ways that we cannot.”

Stell added that the licensing step was “a milestone following 25 years of research, and lots of hard work by Dr. Koufman and the people on her team.”

Since 1981, Koufman has done pio neering research in gastric reflux, particularly that which affects the voice and breathing passages. She coined the term "laryngopharyngeal reflux" to describe the backflow of gastric contents into the throat.

Koufman said laryngopharyngeal reflux remains under-diagnosed and under-treated. “It is a frequent cause of hoarseness, a sensation of a lump in the throat, difficulty swallowing, choking episodes, and respiratory symptoms. It is sometimes difficult to diagnose because it is often silent, occurring without symptoms or heartburn.”

Source: Newswise)
'"/>




Related medicine news :

1. Soft Drinks May Reduce Esophageal Cancer Risk
2. PET Can Predict Response To Treatment In Esophageal Cancer Patients
3. Hiccups May Be An Indication Of Esophageal Cancer
4. Studies Find Connection Between Acid Reflux And Esophageal Cancer
5. Rise in Esophageal Cancer is emphasized by Richards’ deat
6. Esophageal Cancer Rates Climb With Obesity
7. The Causes Of Acid Reflux Questioned
8. Acid Reflux Increases Risk Of Esophagus Cancer
9. Gastric Bypass And Laparoscopic Reflux Surgery Gaining Popularity
10. New Reflux Disease Technology More Comfortable, Not More Effective
11. Studies Find Connection Between Acid Reflux And Esophageal Cancer
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:10/13/2017)... ... , ... “The Journey: From the Mountains to the Mission Field”: the story ... the Philippines. “The Journey: From the Mountains to the Mission Field” is the creation ... has taught all ages and currently teaches a class of ladies at her church, ...
(Date:10/12/2017)... ... October 12, 2017 , ... ... sleep apnea using cutting-edge Oventus O2Vent technology. As many as 18 ... characterized by frequent cessation in breathing. Oral appliances can offer significant relief to ...
(Date:10/12/2017)... ... October 12, 2017 , ... IsoComforter, Inc. ( ... today the introduction of an innovative new design of the shoulder pad. The ... get maximum comfort while controlling your pain while using cold therapy. By utilizing ice ...
(Date:10/12/2017)... ... October 12, 2017 , ... Information about the technology: , ... to enable prevention of a major side effect of chemotherapy in children. Cisplatin ... patients. For cisplatin, hearing loss is FDA listed on-label as a dose limiting ...
(Date:10/12/2017)... D.C. (PRWEB) , ... October 12, 2017 , ... Leading ... their peers in Washington, D.C., for the 49th Congress of the International Society ... ., Vice President of the Center for Cancer and Blood Disorders at ...
Breaking Medicine News(10 mins):
(Date:10/11/2017)... , Oct. 11, 2017  Caris Life Sciences ... on fulfilling the promise of precision medicine, today announced ... joined Caris, Precision Oncology Alliance™ (POA) as its 17 ... centers, the St. Jude Crosson Cancer Institute will help ... the use of tumor profiling, making cancer treatment more ...
(Date:10/10/2017)... COUNTY, Calif. , Oct. 10, 2017  NDS received FDA ... Mobile  — a medical-grade battery-powered display stand specifically designed for endoscopy ... to transform technology into a clinical solution to support the improvement ... Innovative Design ... ZeroWire Mobile Wireless Solution ...
(Date:10/5/2017)... ROSEMONT, Ill. , Oct. 5, 2017 /PRNewswire-USNewswire/ ... American Association of Oral and Maxillofacial Surgeons (AAOMS) ... than opioids – to be used as a ... post-surgical pain. ... relationship, the AAOMS White Paper "Opioid Prescribing: Acute ...
Breaking Medicine Technology: