Navigation Links
Test for Esophageal Reflux Licensed to Bayer by University

A new test for esophageal reflux disease developed by a Wake Forest University Health Sciences (WFUHS) otolaryngologist has been licensed to Bayer HealthCare’s Diagnostics Division by WFUHS.//

The test, which detects the presence of human pepsin 3b in a patient’s saliva, was developed by Jamie Koufman, M.D., then professor of otolaryngology at Wake Forest University School of Medicine and director of WFUHS’s Center for Voice Disorders. She is now director of the Voice Institute of New York.

The test potentially could be used in the offices of primary care physicians and avoid the need for more elaborate and expensive tests. Bayer will market the test.

“Most people associate heartburn with excess stomach acid, but it is the digestive enzyme pepsin (and not acid) bathing the lower area of the esophagus that causes the damage,” said Koufman. “For patients with severe esophagitis, the tissue in the esophagus is literally being self-digested.”

“Besides helping to diagnose gastroesophageal reflux disease, or ‘GERD,’ detecting pepsin in saliva also should help diagnose laryngopharyngeal reflux disease, the backflow of stomach contents into the throat,” she said. “Laryngopharyngeal reflux disease is even more difficult to diagnose than GERD. Scientific evidence points to aerosolized pepsin being drawn into the respiratory system as a common culprit of chronic cough, asthma, and even sinusitis.”

Dean Stell, associate director of the Office of Technology Asset Management, said, “Bayer is a world leader in point-of-care diagnostics and is well qualified to handle the next stage of development. That is the essence of technology transfer – working with our industrial counterparts who can develop technology in ways that we cannot.”

Stell added that the licensing step was “a milestone following 25 years of research, and lots of hard work by Dr. Koufman and the people on her team.”

Since 1981, Koufman has done pio neering research in gastric reflux, particularly that which affects the voice and breathing passages. She coined the term "laryngopharyngeal reflux" to describe the backflow of gastric contents into the throat.

Koufman said laryngopharyngeal reflux remains under-diagnosed and under-treated. “It is a frequent cause of hoarseness, a sensation of a lump in the throat, difficulty swallowing, choking episodes, and respiratory symptoms. It is sometimes difficult to diagnose because it is often silent, occurring without symptoms or heartburn.”

Source: Newswise)
'"/>




Related medicine news :

1. Soft Drinks May Reduce Esophageal Cancer Risk
2. PET Can Predict Response To Treatment In Esophageal Cancer Patients
3. Hiccups May Be An Indication Of Esophageal Cancer
4. Studies Find Connection Between Acid Reflux And Esophageal Cancer
5. Rise in Esophageal Cancer is emphasized by Richards’ deat
6. Esophageal Cancer Rates Climb With Obesity
7. The Causes Of Acid Reflux Questioned
8. Acid Reflux Increases Risk Of Esophagus Cancer
9. Gastric Bypass And Laparoscopic Reflux Surgery Gaining Popularity
10. New Reflux Disease Technology More Comfortable, Not More Effective
11. Studies Find Connection Between Acid Reflux And Esophageal Cancer
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:4/28/2017)... ... April 28, 2017 , ... Children and adolescents who ... experiences than children in the general population. That’s because foster care is designed ... family challenges. While no fault of their own, youth who have experienced trauma ...
(Date:4/28/2017)... , ... April 28, 2017 , ... ... hERG liability could substantially improve drug safety and minimize the cost of development. ... validating ion channel inhibition using cell lines and for cardiac toxicity using induced ...
(Date:4/28/2017)... ... 28, 2017 , ... Yisrayl Hawkins, Pastor and Overseer at The House of Yahweh in Abilene, ... to and which He does not. Yisrayl says with so many titles and names ... name, but he says with a little Scripture, backed with a lot of research, the ...
(Date:4/28/2017)... ... 28, 2017 , ... Intellitec Solutions announced the publication of ... Microsoft Dynamics GP solution that integrates to their PointClickCare EHR software package. With ... care, Brooke Grove now has the capability to achieve its goal for a ...
(Date:4/28/2017)... ... April 28, 2017 , ... Rob Lowe is a popular actor ... leant his presence to an educational purpose as the host of the “Informed” series. ... cancer. In a recent episode, the series focuses on thyroid cancer. , Although thyroid ...
Breaking Medicine News(10 mins):
(Date:4/20/2017)... DUBLIN , April 20, 2017 ... "Latin America Pharmaceutical Contract Manufacturing Services Market Analysis By Service ... And Segment Forecasts, 2014 - 2025" report to their ... The Latin ... USD 21.0 billion by 2025 Low drug registration ...
(Date:4/19/2017)... , April 19, 2017  IRIDEX Corporation (Nasdaq: ... release financial results for the first quarter 2017 after ... The Company,s management team will host a corresponding conference ... ET. Investors interested in listening to the ... for domestic callers or (703) 326-3030 for international callers, ...
(Date:4/19/2017)... 19, 2017 The Global Effective Microorganisms ... 2022 report has covered and analysed the potential of Global ... market size, shares and growth factors. The report identifies and ... opportunities in the global market. ... Browse 152 Tables and Figures, 6 Major Company Profiles, ...
Breaking Medicine Technology: