Navigation Links
Team Tracks Genetic Origins of Eye Cancer

A West Virginia University professor and two alumni have tracked the chromosomal abnormalities associated with a tumor that develops in the eye and often leads to blindness and death.// They're hopeful their findings could someday lead to improved treatment for those who suffer from it.

Joginder Nath, professor of genetics and developmental biology, and former doctoral students Jason White ('02) and Alison Director-Myska ('96) published their findings in two recent issues of Cancer Genetics and Cytogenetics.

The first paper, published in July, describes the specific differences in chromosomal material in cell lines established from sample tissue of these tumors. The second, published in the October issue, describes similar anomalies observed in nearly 100 patients.

Both articles reflect research that comprised a large part of White's doctoral research at WVU. Much of the research was conducted at the Armed Forces Institute of Pathology in Rockville, Md., where Director-Myska headed a lab studying chromosomal aberrations.

"Uveal melanoma develops within the eye, and it's commonly detected when vision begins to be affected," White explained. "By this time, the tumor has grown quite large, and it then migrates to the liver. Once this has occurred, the prognosis is quite poor."

Treatment is often aggressive, involving removal of the eye, though more conservative alternatives are being explored and developed.

The WVU team studied these tumors at the chromosomal level. They studied cell lines from tumor tissue samples, and found common rearrangements in chromosomal configurations.

White found these rearrangements using three different techniques: fluorescence in situ hybridization (FISH), comparative genomic hybridization (CGH), and spectral karyotyping (SKY). FISH involves the fluorescent labeling of a piece of DNA to determine where that piece of DNA is found and how many copies there are
'"/>




Page: 1 2

Related medicine news :

1. Stop HIV/AIDS in its Tracks with Education
2. CDC Study Tracks Levels of Heart Diseases Across the U.S.
3. New Imaging Technique Tracks Traffic Patterns of White Blood Cells
4. Genetic Dentistry: Your Dentist may be able to grow you a new set of Teeth.
5. Genetic influence in menopause
6. Genetics and cholesterol levels
7. Genetics helps in attacking cancer
8. Genetic disorder related with sleep patterns
9. Genetic innovation
10. Genetic tests for cancer
11. Genetic indicates memory
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Team Tracks Genetic Origins Eye Cancer

(Date:1/22/2015)... 2015 VogueQueen is a seasoned and trusted ... many designers are thrilled to have it lead the wedding ... new collection of prom dresses for the global market. , ... strategic vision and he focuses on continuing the goal of ...
(Date:1/22/2015)... Angelweddingdress is a famous wedding dress company offering ... follow it on Facebook, Twitter, and Pinterest. The fans will ... draws a lottery every week. , Moreover, the company has ... Click Angelweddingdress homepage for more information. , ...
(Date:1/22/2015)... AngelWeddingDress, the premier women’s dress supplier, has recently ... View website of AngelWeddingDress.com to find more details. ... online for a bridal party. AngelWeddingDress offers a variety ... Its maternity wedding dresses are specially designed for 2015. ...
(Date:1/22/2015)... Juvent Sports ( http://www.juventsports.com ) and David Leadbetter ... to bestow a Juvent Sports Achievement award upon an ... The award commemorated and congratulated McKitrick for her record ... her first amateur tournament in 1979 and most recently ...
(Date:1/22/2015)... 2015 Thousand of GranuFlo lawsuits ( ... its GranuFlo and NaturaLyte dialysis concentrates continue to move ... District Court, District of Massachusetts, Bernstein Liebhard LLP reports. ... has remanded a case filed by the state of ...
Breaking Medicine News(10 mins):Health News:VogueQueen Unveils New Designs of Prom Dresses for 2015 2Health News:Angelweddingdress Invites Its Customers To Follow It On Facebook, Twitter, And Pinterest 2Health News:AngelWeddingDress Has Recently Released Its Collection Of 2015 Maternity Wedding Dresses 2Health News:All-Time Leading Female Amateur Golfer Arlene McKitrick Receives Juvent Sports Achievement Award at 2015 PGA Show 2Health News:All-Time Leading Female Amateur Golfer Arlene McKitrick Receives Juvent Sports Achievement Award at 2015 PGA Show 3Health News:Court Overseeing Federal GranuFlo Lawsuits Remands Louisiana Claim Back to State Court, Bernstein Liebhard LLP Reports 2Health News:Court Overseeing Federal GranuFlo Lawsuits Remands Louisiana Claim Back to State Court, Bernstein Liebhard LLP Reports 3Health News:Court Overseeing Federal GranuFlo Lawsuits Remands Louisiana Claim Back to State Court, Bernstein Liebhard LLP Reports 4
... survey which was conducted in Delhi, Mumbai, Chennai, Hyderabad and Kolkata ... of the harmful effects of ultra-violet (UV) rays. // The results ... that UV rays affect the eyes. About 73% of the people ... also found that people do not take any precaution to protect ...
... Minister Manmohan Singh underwent a minor surgical procedure on his ... this morning. // ,'The operation on the left ... October 13, 2005. This completes the procedure advised by doctors ... Prime Minister's media advisor Sanjaya Baru said in a statement., ...
... immolation at the Ramlila grounds in New Delhi at a ... // The student had 15 percent burns and was admitted ... Delhi and Kanpur are to go at a hunger strike ... Union Health Ministry has issued orders to nine central medical ...
... from high blood pressure, heart disease and a number ... arteries // , overactive thyroid gland not to take ... there is an increase in the number of cases ... also asked the patients to consult their doctors before ...
... over the past three years has found that increasingly stress ... of the people. // More than 50 percent of the ... condition that increases the risk of heart attack and stroke, ... the people in the age group of 40-70 years were ...
... study conducted by Readers Digest Magazine for a poll it ... and psychic powers. // About 50% of them said that ... surveyed about 1,006 adults and 43% said that they could ... expert. About 50% said that they had dreamt of an ...
Cached Medicine News:
(Date:1/23/2015)... 2015  Pete Rose, baseball,s all-time hits leader, is the new ... Myoflex, Ducere Pharma has announced. "Pete,s a Hall ... have him on board with Myoflex," said Ducere Pharma Chief ... player who is known across all generations. The passion and ...
(Date:1/23/2015)...  iMD Companies, Inc. (ICBU) has repositioned itself as a holding ... a foothold in the hydroponic, hemp and medical marijuana sectors. ... in the sector, and recently partnering with the Chippewa Tribe ... medical marijuana, iMD is committing to bring its vision to ...
(Date:1/23/2015)... 23, 2015   Leatt Corporation  (OTCQB: LEAT), a global ... all forms of sports, including extreme motor sports, and ... today that the UISP Lega Motociclismo Lombardia, an Italian ... to wear a neck brace during its racing competitions.  ...
Breaking Medicine Technology:Pete Rose bets on Myoflex to relieve aches and pains 2iMD Companies Poised to Make Impact in Multi-Billion Dollar Medical Marijuana Sector With Recent Investments and Strategic Partnerships 2Leatt Announces Neck Braces Now Required For Motocross/Minicross Racing In Italy 2Leatt Announces Neck Braces Now Required For Motocross/Minicross Racing In Italy 3
... 7, 2011 Assured Pharmacy (APHY: pinksheets), a leading ... 3,000 sufferers of chronic pain, has filed a Certificate ... a 1-for-180 reverse stock split of the authorized common ... split in the number of issued and outstanding common ...
... VIEJO, Calif., April 7, 2011 Avanir Pharmaceuticals, Inc. ... from a number of clinical research activities will be highlighted ... Neurology (AAN), taking place in Honolulu, HI, at the Hawaii ... about the data presentations:Title: Burden of Pseudobulbar Affect on Social ...
Cached Medicine Technology:Assured Pharmacy Announces Reverse Stock Split 2Assured Pharmacy Announces Reverse Stock Split 3Avanir Pharmaceuticals to Present Data at the American Academy of Neurology Annual Meeting 2Avanir Pharmaceuticals to Present Data at the American Academy of Neurology Annual Meeting 3Avanir Pharmaceuticals to Present Data at the American Academy of Neurology Annual Meeting 4
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
Medicine Products: