Navigation Links
Tamoxifen does not adversely affect the brain

The breast cancer drug tamoxifen does not damage the brains of elderly women, alleviating fears of a neurotoxic effect of such treatment, recent study has revealed. According to researchers, tamoxifen has a similar effect on the brain to oestrogen, which has been linked with potentially neuroprotective action //against cognitive decline.

The researchers used proton magnetic resonance spectroscopy to determine levels of the cerebral metabolite myo-inositol, which has been found at elevated levels during brain injury, in the brains of 80 women. Sixteen of the women were breast cancer patients who had received tamoxifen therapy for at least two years beforehand, 27 were healthy women who had received preventative oestrogen-based hormone replacement therapy (HRT) for at least two years and 33 were healthy women who had received neither tamoxifen nor HRT.

Dr Ernst and colleagues found that women who had received tamoxifen or oestrogen had lower levels of myo-inositol than the controls who had received neither treatment. The women who had received tamoxifen for the longest period of time had the lowest levels of the metabolite present in their brains.

The researchers concluded that both tamoxifen and oestrogen may have neuroprotective effects, and may modulate the effect on the brain. They added that further research is needed to determine the effects of oestrogen and tamoxifen on cognition.
'"/>




Page: 1

Related medicine news :

1. Letrozole Beats Tamoxifen in Breast Cancer Therapy
2. Tamoxifen reduces breast cancer risk
3. Tamoxifen reduces breast cancer risk
4. Aromatase Inhibitors drug Femara after Tamoxifen therapy protects from breast cancer recurrence
5. Tamoxifen Ineffective In Presence Of Genetic Variation in Breast Cancer
6. New Drug More Effective than Tamoxifen in Preventing Breast Cancer Relapse
7. Raloxifene Better Than Tamoxifen For Breast Cancer
8. Aromatase Inhibitors Better Than Tamoxifen For Treating Receptor-Positive Early Breast Cancer
9. Study Identifies Mechanism Which May Help Tamoxifen Work Better
10. Tamoxifen Discontinuation Rates Surprisingly High
11. Tamoxifen Yields Long-term Reduction in Breast Cancer Risk
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:10/13/2017)... ... October 13, 2017 , ... As health professionals work ... as “patient engagement.” The patient is doing more than filling out a survey; in ... “There is an increasing emphasis in health care and research on the importance of ...
(Date:10/13/2017)... ... , ... PurhealthRX , a leading Health and Nutrition Company, is announcing ... full spectrum CBD oil will revolutionize the rapidly growing CBD market by reducing the ... incorporated into liquid products, while reducing costs to end users. , The team of ...
(Date:10/13/2017)... ... October 13, 2017 , ... Many families have long-term insurance ... care insurance companies have a waiver for care if the client has a cognitive ... the family pays for care, is often waived, so the benefits from their insurance ...
(Date:10/13/2017)... ... October 13, 2017 , ... Yisrayl Hawkins, Pastor and Overseer at ... of the most popular and least understood books in the Holy Scriptures, Revelation. The ... that have baffled scholars for centuries. Many have tossed it off as mere rubbish, ...
(Date:10/13/2017)... ... ... “America On The Brink”: the Christian history of the United States and the ... published author, William Nowers. Captain Nowers and his wife, Millie, have six children, ... in the Navy. Following his career as a naval aviator and carrier pilot, ...
Breaking Medicine News(10 mins):
(Date:9/27/2017)... NEW YORK , Sept. 27, 2017  DarioHealth Corp. (NASDAQ: ... data solutions, today announced that its MyDario product is expected to appear ... listings for when The Dr. Oz Show airs in your area: ... The nine-time Emmy award-winning, The ... ...
(Date:9/22/2017)... 2017  As the latest Obamacare repeal effort moves ... (R-LA) and Lindsey Graham (R-SC) medical ... device industry is in an odd place.  The industry ... excise tax on medical device sales passed along with ... patients, increased visits and hospital customers with the funding ...
(Date:9/18/2017)... Pa. and KALAMAZOO, Mich. , Sept. 18, ... , and OptiMed Specialty Pharmacy of ... to offer a strategic hub service that expedites and ... sought-after personal spirometer, Spiro PD 2.0, and wellness management ... spirometer is a medical device used to measure lung ...
Breaking Medicine Technology: