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TEMPE Spray Delays Ejaculation

A new study suggests that TEMPE, a topical anesthetic spray has the potential to offer a convenient, novel treatment for men with premature ejaculation and might be useful// as a first-line treatment for the condition. This study is published in the February issue of the urology journal BJU International.

Researchers from the UK and Netherlands studied 54 men with premature ejaculation, randomly assigning them to a treatment and control group. Both groups reported that without any therapy they normally ejaculated an average of one minute after vaginal penetration.

"The men who were prescribed the TEMPE spray, which delivers a combination of lidocaine and prilocaine, managed to delay ejaculation by just under an extra four minutes after using the product" reports Professor Wallace Dinsmore from the Royal Victoria Hospital, Belfast.

"Meanwhile the control group, who were prescribed a placebo (dummy) spray, increased their penetration to ejaculation time by just over 40 seconds.

"Overall, the TEMPE spray was 2.4 times more effective than the placebo."

The study focussed on heterosexual couples who had been in a stable monogamous relationship for at least three months and were willing to attempt sexual intercourse on at least seven occasions during the ten-week study period.

Recruited from six hospitals and medical centres across the UK – Sheffield, Manchester, Durham, Plymouth, Belfast and London – and one in The Hague, the men were aged from 18 to 75, with an average age of 39.

Time since diagnosis ranged from seven months to just under 35 years, with an average of nine and a half years.

The men in the TEMPE group (Topical Eutectic Mixture for Premature Ejaculation) administered three metered sprays of the local anaesthetic preparation to the glans of their penis 15 minutes before intercourse. This delivered a total of 22.5mg of lidocaine and 7.5mg of prilocaine.


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