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TB Vaccines: Ring Out the New, Bring in the Old

: "A number of other approaches are being actively investigated to improve the protection provided by the current BCG vaccine strains.

"Clinical trials over the next five to seven years will provide evidence as to which approach will be most successful."

TB rates have skyrocketed since the 1980s in places such as the former Soviet Union and sub-Saharan Africa.

Dr. Marcel Behr of Montreal's McGill University says the new study is "a clarion call to create a better vaccine." He said one option is to recreate the original BCG genome and "reconstruct something more closely resembling the original bacterium."

The World Health Organization estimates 1.7 million people died from TB in 2004.
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