Navigation Links
TB Vaccines: Ring Out the New, Bring in the Old

Old may be gold, according to the journal Proceedings of the National Academy of Sciences. The report states that the present TB vaccines are losing their efficiency in// preventing tuberculosis, and scientists may do well to resurrect older versions of the vaccine.

The scientists led by Dr. Roland Brosch of the Institut Pasteur opine that modern BCG or bacillus Calmette Guerin vaccines used in immunization of 2 million children around the world weekly, are losing their power, probably due to changes in the genetic strains used.

The evolution of these strains and the subsequent loss of certain genes, are creating weaker immune reactions, note the scientists.

French scientists originally developed the BCG vaccine, which has been running for the last 90 years, in 1908. They managed to make a strain of tuberculosis (TB) less potent by growing it in a glycerin-potato mixture.

This meant when used in a vaccine it would produce an immune response without causing the actual disease. Once they found it was safe, they began to distribute the vaccine around the world.

Since the 1960s, there have been reports of the declining efficacy of the BCG vaccine.

A study in babies published in 2006 found that the early Japan strain prompted a stronger immune reaction than three newer strains that are used in 66% of modern immunizations.

Study leader, Dr Roland Brosch, senior researcher at the Institut says: "The earlier strains have undergone fewer genetic changes.

"The later strains were selected because they had the least side effects but maybe the efficiency has become less and less."

Brosch advises more research into the matter coupled with methods of making the present vaccines more effective.

The Health Protection Agency of U.K welcomed the research and added that EU sponsored clinical trials were in the process of re-evaluating older strains.

The agency was quoted : "A number of other approaches are being actively investigated to improve the protection provided by the current BCG vaccine strains.

"Clinical trials over the next five to seven years will provide evidence as to which approach will be most successful."

TB rates have skyrocketed since the 1980s in places such as the former Soviet Union and sub-Saharan Africa.

Dr. Marcel Behr of Montreal's McGill University says the new study is "a clarion call to create a better vaccine." He said one option is to recreate the original BCG genome and "reconstruct something more closely resembling the original bacterium."

The World Health Organization estimates 1.7 million people died from TB in 2004.
ANN
'"/>




Related medicine news :

1. Intro of Pneumococcal Vaccines: Experts Urge Commitment From Industry
2. Drug Found To Bring Relief For Individuals With Early Parkinson’
3. Improving Lighting Could Bring About A Change In Alzheimers Patients
4. Researchers Bring New Insight To Asthma And SABA Fills
5. Stardust Brings Interstellar Dust
6. Free HIV Tests Brings Crowd to the Testing Centers
7. East Asian Immigrants Bring Hepatitis to New York
8. Medico’s Return to Work Bringing Respite to Patient
9. Singapore Manufacturer to Bring Ethnic Foods to the World
10. Revamping Of Healthcare System Required To Bring Down Preventable Medical Errors
11. Anesthesia Drug To Bring Solace To The Depressed
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:10/12/2017)... ... October 12, 2017 , ... Information ... we intend to develop to enable prevention of a major side effect of ... loss, especially in pediatric patients. For cisplatin, hearing loss is FDA listed on-label ...
(Date:10/12/2017)... ... October 12, 2017 , ... HMP , a leader in healthcare events ... Magazine Eddie Digital Award for ‘Best B-to-B Healthcare Website.’ Winners were announced during the ... The annual award competition recognizes editorial and design excellence across a range of sectors. ...
(Date:10/12/2017)... ... , ... On Saturday, October 21, the Health & Wellness Center at Florida ... money for the American Heart Association Heart Walk. Teams of up to 10 people ... keep their treadmills moving for 5 hours. Treadmills will start at 7:00 p.m. on ...
(Date:10/12/2017)... , ... October 12, 2017 , ... ... the nation's first interactive health literacy software tool, and the Cancer Patient Education ... of cancer patient education, today announce a new strategic alliance. , As ...
(Date:10/12/2017)... ... October 12, 2017 , ... ... in wound care advancements to physician colleagues, skilled nursing facility medical directors and ... the Treacherous Waters of Wound Care." , "At many of these conferences we ...
Breaking Medicine News(10 mins):
(Date:9/25/2017)... 2017  EpiVax, Inc., a leader in the ... today announced the launch of EpiVax Oncology Inc., ... therapeutic cancer vaccines. EpiVax has provided $500,000 in ... enabling technologies to the new precision immunotherapy venture. ... Oncology as Chief Executive Officer. Gad brings over ...
(Date:9/22/2017)... SAN DIEGO , Sept. 22, 2017 ... ll medical device is now successfully helping those with ... Union. Fibromyalgia diagnosed Amanda in ... getting dressed and washing my hair, experiencing no sleep ... body in painful spasm… I cannot recommend [the AVACEN ...
(Date:9/18/2017)... , Sept. 18, 2017  PMD Healthcare of ... Pharmacy of Kalamazoo, Mich. , have ... service that expedites and streamlines patient and provider access ... 2.0, and wellness management services.  ... used to measure lung function for a variety of ...
Breaking Medicine Technology: