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Systemic Pre-Surgical Treatment Can Prolong Survival Of Kidney Cancer Patients

t can be associated with the response. We want to discover how these targeted therapies produce a response in renal cell carcinoma, what molecules and genes are controlling disease resistance and response, and, specifically, what role is played by the protein VHL, which is frequently mutated in patients with kidney cancer and which is known to be an important driver of angiogenesis.'

In addition, Prof Jonasch and his team are running similar trials with two other targeted therapies, sorafenib and sunitinib.

He said: 'The main aim of this study was to look at the efficacy and safety of using these targeted therapies before surgery, and our results have shown that there were few side effects and that it prolonged the survival of our patients.'

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