Navigation Links
Symptoms of Depression Associated With Artery Diseases

According to a report in the February issue of Archives of General Psychiatry, one of the JAMA/Archives journals, depressive symptoms—especially physical signs, such as// fatigue and loss of appetite—may be associated with thickening arteries, which may reflect an early sign of coronary artery disease.

Considerable evidence suggests that depression, anger and other negative emotions are associated with the risk for coronary artery disease, which occurs when the vessels carrying blood to the heart become narrowed and thickened. However, most studies have assessed the risk for heart attack or sudden cardiac death, according to background information in the article. Because these events are later steps in the development of coronary artery disease, it is currently unclear whether depression, anxiety and other negative emotions play a role in early disease processes.

Jesse C. Stewart, Ph.D., then at the University of Pittsburgh School of Medicine and now at Indiana University–Purdue University Indianapolis, and colleagues studied 324 men and women who were an average of 60.6 years old.

At the beginning of the study, participants attended 11 visits in a five-month period, including a medical screening; testing for cardiovascular risk factors, including high blood pressure and high cholesterol; questionnaires to assess depression, anxiety, hostility and anger; and ultrasound tests to determine carotid artery intima-media thickness (IMT), a measure of the inner layers of the arteries that is related to early-stage coronary artery disease. Cardiovascular risk factors and IMT were assessed again after three years.

"Regression analyses indicated that higher depressive symptoms at baseline were associated with greater three-year change in carotid intima-media thickness, even after taking into account demographic factors, cardiovascular risk factors, medication use, medical conditions and other correlated negative emotions," the authors w rite. "Measures of anxiety symptoms, hostility, anger experience and anger expression were each unrelated to intima-media thickness change."

To further understand the role of specific depressive symptoms in IMT, the researchers separated the condition down into two components: a somatic-vegetative score, which includes physical indicators such as fatigue and appetite disturbance, and a cognitive-affective score, which includes sadness, pessimism and other emotions associated with depression. Analysis of each component revealed that the somatic-vegetative score, but not the cognitive-affective score, was linked to IMT thickness.

"Taken together, our results indicate that depression, but perhaps not anxiety and hostility/anger, may be involved in the initiation and/or progression of atherosclerosis," or hardening of the arteries, the authors write. "More specifically, our findings suggest that the somatic-vegetative features of depression that are not shared with other negative emotions may play an important role in the earlier stages of coronary artery disease development."

Few previous studies have looked at several negative emotions at once, but this approach will be critical in understanding the links between these psychological variables and physical disease, they conclude. "Identifying these components, in turn, may provide insights into the mechanisms underlying the negative emotion–coronary artery disease relationships and may facilitate the development of focused interventions designed to reduce the coronary artery disease risk of individuals prone to experience negative emotions."

Source-Eurekalert
RI
'"/>




Related medicine news :

1. A hormone may decrease Menopause Symptoms
2. Heart Attack Symptoms in Women
3. Heart Attack Symptoms Different in Women
4. Symptoms Found To Be A Good Predictor Of Cancer Survival
5. Sudden Stress Found To Mimic Heart Attack Symptoms
6. Age Can Changes Symptoms Of Sinusitis
7. Ovarian Cancer Presents ‘Target Symptoms’ Six Months Before Diagnosi
8. Daily Jogging Helps To Reduce Symptoms Of Depression
9. Gluten-Free Diet May Alleviate Psychiatric Symptoms In Adolescents
10. Asthma Patients Under The Care Of An Allergist Report Less Severe Symptoms
11. Girl Foetus Aggravates Asthma Symptoms
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/25/2016)... ... 25, 2016 , ... As a lifelong Southern Californian, Dr. Omkar Marathe earned ... the David Geffen School of Medicine at UCLA. He trained in Internal Medicine at ... fellowship in hematology/oncology at the UCLA-Olive View-Cedars Sinai program where he had the opportunity ...
(Date:6/25/2016)... , ... June 25, 2016 , ... On Friday, June ... a Bronze Wellness at Work award to iHire in recognition of their exemplary accomplishments ... of the 7th annual Maryland Workplace Health & Wellness Symposium at the BWI Marriott ...
(Date:6/24/2016)... Angeles, CA (PRWEB) , ... June 24, 2016 , ... ... surgery procedures that most people are unfamiliar with. The article goes on to state ... procedures, but also many of these less common operations such as calf and cheek ...
(Date:6/24/2016)... ... 2016 , ... June 19, 2016 is World Sickle Cell Observance Day. In ... benefits of holistic treatments, Serenity Recovery Center of Marne, Michigan, has issued ... Sickle Cell Disease (SCD) is a disorder of the red blood cells, which can ...
(Date:6/24/2016)... ... June 24, 2016 , ... The Pulmonary ... Dallas that it will receive two significant new grants to support its work ... marked its 25th anniversary by recognizing patients, medical professionals and scientists for their ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... ANGELES , June 23, 2016 ... CAPR ), a biotechnology company focused ... therapeutics, today announced that patient enrollment in its ... in Duchenne) has exceeded 50% of its 24-patient ... enrollment in the third quarter of 2016, and ...
(Date:6/23/2016)... -- , , , WHEN: , ... , , , LOCATION: , , , Online, with free ... EXPERT PANELISTS:  , , , Frost & Sullivan,s Global Vice President ... Industry Analyst, Divyaa Ravishankar and Unmesh Lal, Program Manager , ... is witnessing an exceptional era. Several new demand spaces, such as ...
(Date:6/23/2016)... 23, 2016 Revolutionary technology includes ... Oticon , industry leaders in advanced audiology and hearing ... Oticon Opn ™, the world,s first internet connected hearing ... IoT devices.      (Photo: http://photos.prnewswire.com/prnh/20160622/382240 ... number of ,world firsts,: , TwinLink™ - ...
Breaking Medicine Technology: