Navigation Links
Symptoms of Depression Associated With Artery Diseases

According to a report in the February issue of Archives of General Psychiatry, one of the JAMA/Archives journals, depressive symptoms—especially physical signs, such as// fatigue and loss of appetite—may be associated with thickening arteries, which may reflect an early sign of coronary artery disease.

Considerable evidence suggests that depression, anger and other negative emotions are associated with the risk for coronary artery disease, which occurs when the vessels carrying blood to the heart become narrowed and thickened. However, most studies have assessed the risk for heart attack or sudden cardiac death, according to background information in the article. Because these events are later steps in the development of coronary artery disease, it is currently unclear whether depression, anxiety and other negative emotions play a role in early disease processes.

Jesse C. Stewart, Ph.D., then at the University of Pittsburgh School of Medicine and now at Indiana University–Purdue University Indianapolis, and colleagues studied 324 men and women who were an average of 60.6 years old.

At the beginning of the study, participants attended 11 visits in a five-month period, including a medical screening; testing for cardiovascular risk factors, including high blood pressure and high cholesterol; questionnaires to assess depression, anxiety, hostility and anger; and ultrasound tests to determine carotid artery intima-media thickness (IMT), a measure of the inner layers of the arteries that is related to early-stage coronary artery disease. Cardiovascular risk factors and IMT were assessed again after three years.

"Regression analyses indicated that higher depressive symptoms at baseline were associated with greater three-year change in carotid intima-media thickness, even after taking into account demographic factors, cardiovascular risk factors, medication use, medical conditions and other correlated negative emotions," the authors w rite. "Measures of anxiety symptoms, hostility, anger experience and anger expression were each unrelated to intima-media thickness change."

To further understand the role of specific depressive symptoms in IMT, the researchers separated the condition down into two components: a somatic-vegetative score, which includes physical indicators such as fatigue and appetite disturbance, and a cognitive-affective score, which includes sadness, pessimism and other emotions associated with depression. Analysis of each component revealed that the somatic-vegetative score, but not the cognitive-affective score, was linked to IMT thickness.

"Taken together, our results indicate that depression, but perhaps not anxiety and hostility/anger, may be involved in the initiation and/or progression of atherosclerosis," or hardening of the arteries, the authors write. "More specifically, our findings suggest that the somatic-vegetative features of depression that are not shared with other negative emotions may play an important role in the earlier stages of coronary artery disease development."

Few previous studies have looked at several negative emotions at once, but this approach will be critical in understanding the links between these psychological variables and physical disease, they conclude. "Identifying these components, in turn, may provide insights into the mechanisms underlying the negative emotion–coronary artery disease relationships and may facilitate the development of focused interventions designed to reduce the coronary artery disease risk of individuals prone to experience negative emotions."

Source-Eurekalert
RI
'"/>




Related medicine news :

1. A hormone may decrease Menopause Symptoms
2. Heart Attack Symptoms in Women
3. Heart Attack Symptoms Different in Women
4. Symptoms Found To Be A Good Predictor Of Cancer Survival
5. Sudden Stress Found To Mimic Heart Attack Symptoms
6. Age Can Changes Symptoms Of Sinusitis
7. Ovarian Cancer Presents ‘Target Symptoms’ Six Months Before Diagnosi
8. Daily Jogging Helps To Reduce Symptoms Of Depression
9. Gluten-Free Diet May Alleviate Psychiatric Symptoms In Adolescents
10. Asthma Patients Under The Care Of An Allergist Report Less Severe Symptoms
11. Girl Foetus Aggravates Asthma Symptoms
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:3/24/2017)... ... March 24, 2017 , ... ... countries to hospitals in the United States, it’s a threat that is constantly ... obstacles facing infection prevention and offers strategies for the healthcare community to help ...
(Date:3/24/2017)... ... ... According to a new study by NCPA Senior Fellow John R. Graham, "the ... has directed the CBO to follow. The CBO itself previously recognized Obamacare would kill ... a reduction in employer-based coverage due to the GOP reform, which is not plausible. ...
(Date:3/24/2017)... ... March 24, 2017 , ... ... and related services to families and business owners across eastern Michigan, is connecting ... regional families struggling with financial difficulties. , The Oxford/Orion FISH Food Pantry works ...
(Date:3/24/2017)... ... March 24, 2017 , ... As the standards ... a communications platform that positions them as the go-to thought leader in all ... online publication as an always-on, always-fresh news, views and advocacy engine, called ONS ...
(Date:3/24/2017)... ... March 24, 2017 , ... The law firm of ... is pleased to announce Westchester resident Lauren C. Enea has joined the firm as ... firm, will concentrate her practice in elder law, Medicaid planning and applications, and Wills, ...
Breaking Medicine News(10 mins):
(Date:3/24/2017)... Research and Markets has announced the addition of the "Global ... ... very strong with a total of 97 drug candidates. Pharma giant such ... involved in the development of the IPF therapeutics. The IPF pipeline comprised ... 15 are in Phase II stage, 12 are in Phase I stage, ...
(Date:3/24/2017)... India , March 24, 2017 ... of the industry including definitions, classifications, applications and industry ... the international market including development history, competitive landscape analysis, ... ... Ampoules industry spread across 105 pages providing 10 company ...
(Date:3/24/2017)... , March 24, 2017  GenomeDx Biosciences today ... Information Database) and Decipher® Prostate Cancer Classifier tests will ... Association of Urology (EAU) Congress held March 24 to ... The Annual EAU Congress is Europe,s ... comprehensive research in the urological field. The ...
Breaking Medicine Technology: