Navigation Links
Switching drugs regularly improves HIV treatment

NEW YORK (Reuters Health) - When HIV-infected patients alternated their drug regimen every three months, their virus levels stayed down longer than when one regimen was administered continuously.
That news comes from the SWATCH (SWitching Antiviral Therapy Combination against HIV-1) study. Dr. Javier Martinez-Picado, of Hospital Germans Trias I Pujol in Badalona, Spain, and others examined this alternating strategy among HIV patients who //were randomized to one of three regimens.
Regimen A consisted of continuous treatment with didanosine, stavudine, and efavirenz. For regimen B, patients were administered zidovudine, lamivudine and nelfinavir. In regimen C, the patients alternated between the other two regimens every 3 months. The results are reported in the Annals of Internal Medicine .
Response to treatment was similar in patients receiving regimen A or regimen B, so the researchers pooled these two groups when evaluating the results.
The rate of virologic failure - that is, a rise in the amount of virus in the blood above a defined level - was 3.5 higher during the following year in the pooled group than in the alternating therapy group.
Dr. Martinez-Picado's group concludes, "Proactive switching and alternation of antiretroviral regimens with drugs that have different resistance profiles might extend the overall long-term effectiveness of first- and second-line treatment options."
In an editorial, Dr. Michael Saag, of the University of Alabama at Birmingham, points out that current drug regimens are more efficacious than the ones used in the SWATCH study.
However, he agrees with Dr. Martinez-Picado's group that further study of proactive switching seems warranted, but that the strategy should not be routine at this time..


Page: 1

Related medicine news :

1. Switching Off Protein Could Play Key Role In Success Of Radiation Therapy For Cancer
2. Switching Genes to Overdrive Improves Muscular Dystrophy Symptoms in Mice
3. Cancer drugs in development nearly doubled since 1995
4. Cipla holds talks with mining giant to supply AIDS drugs for South African workers
5. African HIV strains more resistant to anti HIV drugs
6. Right drugs drastically cut stroke risk
7. Relating heart protection and antihypertensive drugs
8. Enzyme may be target for obesity drugs
9. New HIV cases resist drugs
10. Relief to pregnant women using fertility drugs
11. AIDS drugs linked to heart attack risk
Post Your Comments:

(Date:11/24/2015)... ... November 24, 2015 , ... United ... to welcome Winter-Dent & Company as its newest Partner Firm. Based in Jefferson ... a client's most trusted advisor regardless of whether that client is a business, ...
(Date:11/24/2015)... ... November 24, 2015 , ... Serenity Point Rehabilitation, a holistic treatment center for ... with some of the staff members at their recovery center. The videos highlight some ... as some of the things that make their recovery program so unique. , “Making ...
(Date:11/24/2015)... ... 2015 , ... Abington Hospital – Jefferson Health is pleased ... Surgery Facility for treating individuals living with morbid or extreme obesity. , Aetna ... its members to help them make informed decisions about their healthcare needs. In ...
(Date:11/24/2015)... ... November 24, 2015 , ... American Specialty Health Fitness, ... have announced their endorsement of the Medical Fitness Network (MFN), a national health ... have the MFN as one of our endorsed organizations,” said ASH Fitness Vice ...
(Date:11/24/2015)... ... November 24, 2015 , ... World ... Innovative Blending, a household invention that revolutionizes the vending machine industry by providing ... market is worth $2 billion," says Scott Cooper, CEO and Creative Director of ...
Breaking Medicine News(10 mins):
(Date:11/24/2015)... Nov. 24, 2015 Teledyne DALSA , a ... sensing technology, will introduce its CMOS X-Ray detector for ... November 29 to December 3, at McCormick Place in ... for diagnostic and interventional imaging will be on display in ... of advanced CMOS X-Ray detectors is the industry benchmark ...
(Date:11/24/2015)... , Nov. 24, 2015  Boston Scientific Corporation (NYSE: ... Oppenheimer 26th Annual Healthcare Conference on December 8, in ... Susie Lisa , vice president, Investor Relations, will participate ... beginning at approximately 8:35 a.m. ET. --> ... in a 30-minute question-and-answer session with the host analyst ...
(Date:11/24/2015)...   Renowned UAE ... s advice and insights on supplements and healthy diet ... 50% of Dubai residents are not ...   femMED launches comprehensive solutions for women , ... residents are not consuming enough to keep themselves healthy. A local ...
Breaking Medicine Technology: