Navigation Links
Switching drugs regularly improves HIV treatment

NEW YORK (Reuters Health) - When HIV-infected patients alternated their drug regimen every three months, their virus levels stayed down longer than when one regimen was administered continuously.
That news comes from the SWATCH (SWitching Antiviral Therapy Combination against HIV-1) study. Dr. Javier Martinez-Picado, of Hospital Germans Trias I Pujol in Badalona, Spain, and others examined this alternating strategy among HIV patients who //were randomized to one of three regimens.
Regimen A consisted of continuous treatment with didanosine, stavudine, and efavirenz. For regimen B, patients were administered zidovudine, lamivudine and nelfinavir. In regimen C, the patients alternated between the other two regimens every 3 months. The results are reported in the Annals of Internal Medicine .
Response to treatment was similar in patients receiving regimen A or regimen B, so the researchers pooled these two groups when evaluating the results.
The rate of virologic failure - that is, a rise in the amount of virus in the blood above a defined level - was 3.5 higher during the following year in the pooled group than in the alternating therapy group.
Dr. Martinez-Picado's group concludes, "Proactive switching and alternation of antiretroviral regimens with drugs that have different resistance profiles might extend the overall long-term effectiveness of first- and second-line treatment options."
In an editorial, Dr. Michael Saag, of the University of Alabama at Birmingham, points out that current drug regimens are more efficacious than the ones used in the SWATCH study.
However, he agrees with Dr. Martinez-Picado's group that further study of proactive switching seems warranted, but that the strategy should not be routine at this time..


'"/>




Page: 1

Related medicine news :

1. Switching Off Protein Could Play Key Role In Success Of Radiation Therapy For Cancer
2. Switching Genes to Overdrive Improves Muscular Dystrophy Symptoms in Mice
3. Cancer drugs in development nearly doubled since 1995
4. Cipla holds talks with mining giant to supply AIDS drugs for South African workers
5. African HIV strains more resistant to anti HIV drugs
6. Right drugs drastically cut stroke risk
7. Relating heart protection and antihypertensive drugs
8. Enzyme may be target for obesity drugs
9. New HIV cases resist drugs
10. Relief to pregnant women using fertility drugs
11. AIDS drugs linked to heart attack risk
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:1/19/2017)... ... January 19, 2017 , ... Wells ... facility enhancement of their 503A compounding pharmacy located in Ocala, Florida. , ... physicians and patients throughout the United States for high-quality human anti-aging and ...
(Date:1/19/2017)... ... January 19, 2017 , ... This month, the CEO and Clinical Director ... their drug rehab center in Delray Beach, Florida has been changed from Sober Living ... such as Philip Seymour Hoffman and Chris Farley are dying from heroin overdoses, but ...
(Date:1/19/2017)... ... 2017 , ... WhoHaha , a digital media company dedicated to creating ... to produce a three-part video series that uses humor to highlight ways to improve ... of AHA’s Healthy For Good™ movement, which is designed to inspire all Americans to ...
(Date:1/19/2017)... ... January 19, 2017 , ... Cosmetic Town, an online plastic surgery community, begins ... make it easier for their readers to get the information they desire. The procedures ... as the techniques used on those particular areas. , “We are excited to streamline ...
(Date:1/19/2017)... ... January 19, 2017 , ... Catalent ... for drugs, biologics and consumer health products, today announced that it will be ... leader in innovative excipients and drug delivery solutions to health industries worldwide. The ...
Breaking Medicine News(10 mins):
(Date:1/19/2017)... 19, 2017 Pfizer joins ... Milner Therapeutics Consortium   Major research ... Cambridge   The Milner Therapeutics ... ) as a partner to the Milner Therapeutics Consortium. ... the efficient transfer of materials between industry and academia ...
(Date:1/19/2017)... 2017  ViewRay, Inc. (Nasdaq: VRAY ... clinical MRI-guided radiation therapy system, announced today that it ... million through a private placement of its common ... financing and was joined by certain of ViewRay,s ... Venture Partners, and an additional new institutional investor, ...
(Date:1/19/2017)... , Jan. 18, 2017 The ... Food and Drug Administration (FDA) for its release ... and population health decision makers can proactively share ... products as well as emerging therapies awaiting FDA ... mirrors consensus recommendations that AMCP developed during two ...
Breaking Medicine Technology: